Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening
McLean, Larry R., Zhang, Ying, Li, Hua, Li, Ziyu, Lukasczyk, Ulrike, Choi, Yong-Mi, Han, Zuoning, Prisco, Joy, Fordham, Jeremy, Tsay, Joseph T., Reiling, Stephan, Vaz, Roy J., Li, Yi
Published in Bioorganic & medicinal chemistry letters (01.12.2009)
Published in Bioorganic & medicinal chemistry letters (01.12.2009)
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Journal Article
Discovery of novel inhibitors for DHODH via virtual screening and X-ray crystallographic structures
McLean, Larry R., Zhang, Ying, Degnen, William, Peppard, Jane, Cabel, Dasha, Zou, Chao, Tsay, Joseph T., Subramaniam, Arun, Vaz, Roy J., Li, Yi
Published in Bioorganic & medicinal chemistry letters (15.03.2010)
Published in Bioorganic & medicinal chemistry letters (15.03.2010)
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Journal Article
Crystal Structure of Human Cyclin-Dependent Kinase 2 in Complex with the Adenine-Derived Inhibitor H717
Dreyer, Matthias K, Borcherding, David R, Dumont, Jennifer A, Peet, Norton P, Tsay, Joseph T, Wright, Paul S, Bitonti, Alan J, Shen, Jian, Kim, Sung-Hou
Published in Journal of medicinal chemistry (15.02.2001)
Published in Journal of medicinal chemistry (15.02.2001)
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Journal Article
Substituted 1H-pyrrolo[2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase Iepsilon
HURST WILLIAM JOSEPH, DUTRUC-ROSSET GILLES, CHIANG YULIN, DOERFLINGER GILLES, CAMACHO FERNANDO, ROEHR JOACHIM E, GELORMINI ANN MARIE, HARNISH STEPHEN WAYNE, METZ, JR. WILLIAM A, POLI GREGORY BERNARD, GIOVANNI ANDREW, HALLEY FRANK, CHOI-SLEDESKI YONG MI, FINK DAVID MARC, GAMBOA JUAN ANOTONIO, HUANG BAO-GUO, TSAY JOSEPH T
Year of Publication 01.12.2009
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Year of Publication 01.12.2009
Patent
Substituted 1H-pyrrolo[2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase Iε
Metz, Jr, William A, Halley, Frank, Dutruc-Rosset, Gilles, Choi-Sledeski, Yong Mi, Poli, Gregory Bernard, Fink, David Marc, Doerflinger, Gilles, Huang, Bao-Guo, Gelormini, Ann Marie, Gamboa, Juan Anotonio, Giovanni, Andrew, Roehr, Joachim E, Tsay, Joseph T, Camacho, Fernando, Hurst, William Joseph, Harnish, Stephen Wayne, Chiang, Yulin
Year of Publication 01.12.2009
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Year of Publication 01.12.2009
Patent
SUBSTITUTED 1H-PYRROLO[3,2-B, 3,2-C, AND 2,3-C]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON
GAMBOA, JUAN A, GELORMINI, ANN MARIE, TSAY, JOSEPH T, HARNISH, STEPHEN W, ROEHR, JOACHIM E, DUTRUC-ROSSET, GILLES, POLI, GREGORY B, METZ, WILLIAM A, FINK, DAVID M, HURST, WILLIAM J, HUANG, BAO-GUO, DOERFLINGER, GILLES, CAMACHO, FERNANDO, CHOI-SLEDESKI, YONG MI, HALLEY, FRANK, CHIANG, YULIN, GIOVANNI, ANDREW
Year of Publication 30.09.2009
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Year of Publication 30.09.2009
Patent
SUBSTITUTED 1H-PYRROLO(3,2-B, 3,2-C, AND 2,3-C)PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON
FRANCK HALLEY, DAVID M. FINK, GILLES DOERFLINGER, JUAN A. GAMBOA, ANN MARIE GELORMINI, JOSEPH T. TSAY, FERNANDO CAMACHO, YONG MI CHOI-SLEDESKI, WILLIAM J. HURST, GILLES DUTRUC-ROSSET, ANDREW GIOVANNI, STEPHEN W. HARNISH, JOACHIM E. ROEHR, BAO-GUO HUANG, WILLIAM A. METZ, GREGORY B. POLI, YULIN CHIANG
Year of Publication 31.08.2009
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Year of Publication 31.08.2009
Patent
SUBSTITUTED 1H-PYRROLO?á3,2-B, 3,2-C, AND 2,3-C?åPYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON
GAMBOA JUAN A, DUTRUC-ROSSET GILLES, HARNISH STEPHEN W, CHIANG YULIN, DOERFLINGER GILLES, CAMACHO FERNANDO, ROEHR JOACHIM E, GELORMINI ANN MARIE, FINK DAVID M, POLI GREGORY B, GIOVANNI ANDREW, METZ WILLIAM A, HALLEY FRANK, CHOI-SLEDESKI YONG MI, HURST WILLIAM J, HUANG BAO-GUO, TSAY JOSEPH T
Year of Publication 31.08.2009
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Year of Publication 31.08.2009
Patent
Substituerede 1H-pyrrolo[3,2-B, 3,2-C og 2,3-C]pyridin-2-carboxamider og relaterede analoger som inhibitorer af casein kinase I epsilon
DUTRUC-ROSSET, GILLES, POLI, GREGORY, B, HARNISH, STEPHEN, W, HURST, WILLIAM, J, HUANG, BAO-GUO, GAMBOA, JUAN, A, DOERFLINGER, GILLES, CAMACHO, FERNANDO, FINK, DAVID, M, HALLEY, FRANK, METZ, WILLIAM, A, CHIANG, YULIN, CHOI-SLEDESKI, YONG, MI, GIOVANNI, ANDREW, TSAY, JOSEPH, T, GELORMINI, ANN, MARIE, ROEHR, JOACHIM, E
Year of Publication 10.08.2009
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Year of Publication 10.08.2009
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SUBSTITUTED 1H-PYRROLO[3,2-B, 3,2-C, AND 2,3-C]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON
DAVID M. FINK, GILLES DOERFLINGER, JUAN A. GAMBOA, WILLIAM, A. METZ, ANN MARIE GELORMINI, JOSEPH T. TSAY, FERNANDO CAMACHO, FRANK HALLEY, YONG MI CHOI-SLEDESKI, WILLIAM J. HURST, GILLES DUTRUC-ROSSET, ANDREW GIOVANNI, STEPHEN W. HARNISH, JOACHIM E. ROEHR, BAO-GUO HUANG, YULIN CHIANG, GREGORY B. POLI
Year of Publication 08.07.2009
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Year of Publication 08.07.2009
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SUBSTITUTED 1H-PYRROLO[3,2-B, 3,2-C, AND 2,3-C]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON
DUTRUC-ROSSET, GILLES, POLI, GREGORY, B, HARNISH, STEPHEN, W, HURST, WILLIAM, J, HUANG, BAO-GUO, GAMBOA, JUAN, A, DOERFLINGER, GILLES, CAMACHO, FERNANDO, FINK, DAVID, M, HALLEY, FRANK, METZ, WILLIAM, A, CHIANG, YULIN, CHOI-SLEDESKI, YONG, MI, GIOVANNI, ANDREW, TSAY, JOSEPH, T, GELORMINI, ANN, MARIE, ROEHR, JOACHIM, E
Year of Publication 15.04.2009
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Year of Publication 15.04.2009
Patent
3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase
Warshawsky, Alan M, Tsay, Joseph T, Janusz, Michael J, Shen, Jian, Flynn, Gary A, Dharanipragada, Ramalinga M, Burkhart, Joseph P, Beight, Douglas W, Patel, Meena V
Year of Publication 11.10.2005
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Year of Publication 11.10.2005
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3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase
PATEL MEENA V, FLYNN GARY A, BURKHART JOSEPH P, BEIGHT DOUGLAS W, WARSHAWSKY ALAN M, JANUSZ MICHAEL J, TSAY JOSEPH T, SHEN JIAN, DHARANIPRAGADA RAMALINGA M
Year of Publication 11.10.2005
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Year of Publication 11.10.2005
Patent
SUBSTITUTED 1H-PYRROLO[3,2-b, 3,2-c, and 2,3-c]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE Ie
HURST WILLIAM JOSEPH, DUTRUC-ROSSET GILLES, CHIANG YULIN, DOERFLINGER GILLES, CAMACHO FERNANDO, ROEHR JOACHIM E, GELORMINI ANN MARIE, HARNISH STEPHEN WAYNE, POLI GREGORY BERNARD, GAMBOA JUAN ANTONIO, GIOVANNI ANDREW, METZ WILLIAM A, HALLEY FRANK, CHOI-SLEDESKI YONG MI, FINK DAVID MARC, HUANG BAO-GUO, TSAY JOSEPH T
Year of Publication 21.08.2008
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Year of Publication 21.08.2008
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Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase lepsilon
HURST WILLIAM JOSEPH, DUTRUC-ROSSET GILLES, CHIANG YULIN, DOERFLINGER GILLES, CAMACHO FERNANDO, ROEHR JOACHIM E, GELORMINI ANN MARIE, HARNISH STEPHEN WAYNE, METZ, JR. WILLIAM A, POLI GREGORY BERNARD, GAMBOA JUAN ANTONIO, GIOVANNI ANDREW, HALLEY FRANK, CHOI-SLEDESKI YONG MI, FINK DAVID MARC, HUANG BAO-GUO, TSAY JOSEPH T
Year of Publication 22.07.2008
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Year of Publication 22.07.2008
Patent
Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase lepsilon
Metz, Jr, William A, Halley, Frank, Dutruc-Rosset, Gilles, Choi-Sledeski, Yong Mi, Poli, Gregory Bernard, Fink, David Marc, Doerflinger, Gilles, Huang, Bao-Guo, Gelormini, Ann Marie, Gamboa, Juan Antonio, Giovanni, Andrew, Roehr, Joachim E, Tsay, Joseph T, Camacho, Fernando, Hurst, William Joseph, Harnish, Stephen Wayne, Chiang, Yulin
Year of Publication 22.07.2008
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Year of Publication 22.07.2008
Patent
SUBSTITUTED 1H-PYRROLO [3,2-B, 3,2-C, AND 2,3-C]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON
DUTRUC-ROSSET, GILLES, POLI, GREGORY, B, HARNISH, STEPHEN, W, HURST, WILLIAM, J, HUANG, BAO-GUO, GAMBOA, JUAN, A, DOERFLINGER, GILLES, CAMACHO, FERNANDO, FINK, DAVID, M, HALLEY, FRANK, METZ, WILLIAM, A, CHIANG, YULIN, CHOI-SLEDESKI, YONG, MI, GIOVANNI, ANDREW, TSAY, JOSEPH, T, GELORMINI, ANN, MARIE, ROEHR, JOACHIM, E
Year of Publication 27.07.2007
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Year of Publication 27.07.2007
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SUBSTITUTED 1H-PYRROLO(3,2-B, 3,2-C, AND 2,3-C)PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON
DUTRUC-ROSSET, GILLES, POLI, GREGORY, B, HARNISH, STEPHEN, W, HURST, WILLIAM, J, HUANG, BAO-GUO, GAMBOA, JUAN, A, DOERFLINGER, GILLES, CAMACHO, FERNANDO, FINK, DAVID, M, HALLEY, FRANK, METZ, WILLIAM, A, CHIANG, YULIN, CHOI-SLEDESKI, YONG, MI, GIOVANNI, ANDREW, TSAY, JOSEPH, T, GELORMINI, ANN, MARIE, ROEHR, JOACHIM, E
Year of Publication 31.01.2007
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Year of Publication 31.01.2007
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SUBSTITUTED 1H-PYRROLO[3,2-B, 3,2-C, AND 2,3-C]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE Iepsilon
GAMBOA JUAN A, HARNISH STEPHEN W, CHIANG YULIN, DOERFLINGER GILLES, CAMACHO FERNANDO, DUTRUC ROSSET GILLES, ROEHR JOACHIM E, GELORMINI ANN MARIE, CHOI SLEDESKI YONG MI, FINK DAVID M, POLI GREGORY B, GIOVANNI ANDREW, METZ WILLIAM A, HALLEY FRANK, HURST WILLIAM J, TSAY JOSEPH T, HUANG BAO GUO
Year of Publication 02.11.2006
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Year of Publication 02.11.2006
Patent
Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase I Epsilon
DAVID M. FINK, GILLES DOERFLINGER, JUAN A. GAMBOA, ANN MARIE GELORMINI, JOSEPH T. TSAY, FERNANDO CAMACHO, FRANK HALLEY, YONG MI CHOI-SLEDESKI, WILLIAM J. HURST, GILLES DUTRUC-ROSSET, STEPHEN W. HARNISH, ANDREW GIOVANNI, JOACHIM E. ROEHR, BAO-GUO HUANG, GREGORY B. POLI, YULIN CHIANG, WILLIAM A. METZ
Year of Publication 07.07.2005
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Year of Publication 07.07.2005
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