Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure
Levin, Michael G., Tsao, Noah L., Singhal, Pankhuri, Liu, Chang, Vy, Ha My T., Paranjpe, Ishan, Backman, Joshua D., Bellomo, Tiffany R., Bone, William P., Biddinger, Kiran J., Hui, Qin, Dikilitas, Ozan, Satterfield, Benjamin A., Yang, Yifan, Morley, Michael P., Bradford, Yuki, Burke, Megan, Reza, Nosheen, Charest, Brian, Judy, Renae L., Puckelwartz, Megan J., Hakonarson, Hakon, Khan, Atlas, Kottyan, Leah C., Kullo, Iftikhar, Luo, Yuan, McNally, Elizabeth M., Rasmussen-Torvik, Laura J., Day, Sharlene M., Do, Ron, Phillips, Lawrence S., Ellinor, Patrick T., Nadkarni, Girish N., Ritchie, Marylyn D., Arany, Zoltan, Cappola, Thomas P., Margulies, Kenneth B., Aragam, Krishna G., Haggerty, Christopher M., Joseph, Jacob, Sun, Yan V., Voight, Benjamin F., Damrauer, Scott M.
Published in Nature communications (14.11.2022)
Published in Nature communications (14.11.2022)
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Journal Article
MitoScape: A big-data, machine-learning platform for obtaining mitochondrial DNA from next-generation sequencing data
Singh, Larry N, Ennis, Brian, Loneragan, Bryn, Tsao, Noah L, Lopez Sanchez, M Isabel G, Li, Jianping, Acheampong, Patrick, Tran, Oanh, Trounce, Ian A, Zhu, Yuankun, Potluri, Prasanth, Emanuel, Beverly S, Rader, Daniel J, Arany, Zoltan, Damrauer, Scott M, Resnick, Adam C, Anderson, Stewart A, Wallace, Douglas C
Published in PLoS computational biology (01.11.2021)
Published in PLoS computational biology (01.11.2021)
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Journal Article
Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors
Shakt, Gabrielle, Tsao, Noah L, Levin, Michael G, Walker, Venexia, Kember, Rachel L, Klarin, Derek, Tsao, Phil, Voight, Benjamin F, Scali, Salvatore T, Damrauer, Scott M
Published in Journal of the American Heart Association (20.02.2024)
Published in Journal of the American Heart Association (20.02.2024)
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Journal Article
Derivation and Validation of Genome-Wide Polygenic Score for Ischemic Heart Failure
Paranjpe, Ishan, Tsao, Noah L, De Freitas, Jessica K, Judy, Renae, Chaudhary, Kumardeep, Forrest, Iain S, Jaladanki, Suraj K, Paranjpe, Manish, Sharma, Pranav, Glicksberg, Benjamin S, Narula, Jagat, Do, Ron, Damrauer, Scott M, Nadkarni, Girish N
Published in Journal of the American Heart Association (16.11.2021)
Published in Journal of the American Heart Association (16.11.2021)
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Journal Article
Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease
Yu, Mengyao, Tcheandjieu, Catherine, Georges, Adrien, Xiao, Ke, Tejeda, Helio, Dina, Christian, Le Tourneau, Thierry, Fiterau, Madalina, Judy, Renae, Tsao, Noah L, Amgalan, Dulguun, Munger, Chad J, Engreitz, Jesse M, Damrauer, Scott M, Bouatia-Naji, Nabila, Priest, James R
Published in JCI insight (08.02.2022)
Published in JCI insight (08.02.2022)
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Journal Article
Metabolite patterns associated with individual response to supervised exercise therapy in patients with intermittent claudication
Bellomo, Tiffany R., Tsao, Noah L., Johnston-Cox, Hillary, Borkowski, Kamil, Shakt, Gabrielle, Judy, Renae, Moore, Jonni, Ractcliffe, Sarah J., Fiehn, Oliver, Floyd, Thomas F., Wehrli, Felix W., Mohler, Emile, Newman, John W., Damrauer, Scott M.
Published in JVS-vascular science (01.01.2022)
Published in JVS-vascular science (01.01.2022)
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Journal Article
Genome-wide association study of thoracic aortic aneurysm and dissection in the Million Veteran Program
Klarin, Derek, Devineni, Poornima, Sendamarai, Anoop K., Angueira, Anthony R., Graham, Sarah E., Shen, Ying H., Levin, Michael G., Pirruccello, James P., Surakka, Ida, Karnam, Purushotham R., Roychowdhury, Tanmoy, Li, Yanming, Wang, Minxian, Aragam, Krishna G., Paruchuri, Kaavya, Zuber, Verena, Shakt, Gabrielle E., Tsao, Noah L., Judy, Renae L., Vy, Ha My T., Verma, Shefali S., Rader, Daniel J., Do, Ron, Bavaria, Joseph E., Nadkarni, Girish N., Ritchie, Marylyn D., Burgess, Stephen, Guo, Dong-chuan, Ellinor, Patrick T., LeMaire, Scott A., Milewicz, Dianna M., Willer, Cristen J., Natarajan, Pradeep, Tsao, Philip S., Pyarajan, Saiju, Damrauer, Scott M.
Published in Nature genetics (01.07.2023)
Published in Nature genetics (01.07.2023)
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Journal Article
Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People With Type 2 Diabetes
Kwak, Soo Heon, Hernandez-Cancela, Ryan B, DiCorpo, Daniel A, Condon, David E, Merino, Jordi, Wu, Peitao, Brody, Jennifer A, Yao, Jie, Guo, Xiuqing, Ahmadizar, Fariba, Meyer, Mariah, Sincan, Murat, Mercader, Josep M, Lee, Sujin, Haessler, Jeffrey, Vy, Ha My T, Lin, Zhaotong, Armstrong, Nicole D, Gu, Shaopeng, Tsao, Noah L, Lange, Leslie A, Wang, Ningyuan, Wiggins, Kerri L, Trompet, Stella, Liu, Simin, Loos, Ruth J F, Judy, Renae, Schroeder, Philip H, Hasbani, Natalie R, Bos, Maxime M, Morrison, Alanna C, Jackson, Rebecca D, Reiner, Alexander P, Manson, JoAnn E, Chaudhary, Ninad S, Carmichael, Lynn K, Chen, Yii-Der Ida, Taylor, Kent D, Ghanbari, Mohsen, van Meurs, Joyce, Pitsillides, Achilleas N, Psaty, Bruce M, Noordam, Raymond, Do, Ron, Park, Kyong Soo, Jukema, J Wouter, Kavousi, Maryam, Correa, Adolfo, Rich, Stephen S, Damrauer, Scott M, Hajek, Catherine, Cho, Nam H, Irvin, Marguerite R, Pankow, James S, Nadkarni, Girish N, Sladek, Robert, Goodarzi, Mark O, Florez, Jose C, Chasman, Daniel I, Heckbert, Susan R, Kooperberg, Charles, Dupuis, Josée, Malhotra, Rajeev, de Vries, Paul S, Liu, Ching-Ti, Rotter, Jerome I, Meigs, James B
Published in Diabetes care (01.06.2024)
Published in Diabetes care (01.06.2024)
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Journal Article
A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program
Verma, Anurag, Tsao, Noah L, Thomann, Lauren O, Ho, Yuk-Lam, Iyengar, Sudha K, Luoh, Shiuh-Wen, Carr, Rotonya, Crawford, Dana C, Efird, Jimmy T, Huffman, Jennifer E, Hung, Adriana, Ivey, Kerry L, Levin, Michael G, Lynch, Julie, Natarajan, Pradeep, Pyarajan, Saiju, Bick, Alexander G, Costa, Lauren, Genovese, Giulio, Hauger, Richard, Madduri, Ravi, Pathak, Gita A, Polimanti, Renato, Voight, Benjamin, Vujkovic, Marijana, Zekavat, Seyedeh Maryam, Zhao, Hongyu, Ritchie, Marylyn D, Chang, Kyong-Mi, Cho, Kelly, Casas, Juan P, Tsao, Philip S, Gaziano, J Michael, O'Donnell, Christopher, Damrauer, Scott M, Liao, Katherine P
Published in PLoS genetics (28.04.2022)
Published in PLoS genetics (28.04.2022)
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Journal Article
Abstract 3119: Angiographic Burden Of Coronary Atherosclerosis Contributes To Adverse ASCVD Outcomes Independent Of Traditional Risk Factors
Tsao, Noah L, Abramowitz, Sarah, Shakt, Gabrielle, Judy, Renae, Damrauer, Scott M, Levin, Michael
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2024)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2024)
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Journal Article
Evaluation of the Performance of the RECODe Equation with the Addition of Polygenic Risk Scores for Adverse Cardiovascular Outcomes in Individuals with Type II Diabetes
Tsao, Noah L, Judy, Renae, Levin, Michael G, Shakt, Gabrielle, Voight, Benjamin F, Chen, Jinbo, Damrauer, Scott M
Published in medRxiv : the preprint server for health sciences (05.05.2023)
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Published in medRxiv : the preprint server for health sciences (05.05.2023)
Journal Article
Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk
Georgakis, Marios K, Malik, Rainer, El Bounkari, Omar, Hasbani, Natalie R, Li, Jiang, Huffman, Jennifer E, Shakt, Gabrielle, Tack, Reinier W P, Kimball, Tamara N, Asare, Yaw, Morrison, Alanna C, Tsao, Noah L, Judy, Renae, Mitchell, Braxton D, Xu, Huichun, Montasser, May E, Do, Ron, Kenny, Eimear E, Loos, Ruth J F, Terry, James G, Carr, John Jeffrey, Bis, Joshua C, Psaty, Bruce M, Longstreth, W T, Young, Kendra A, Lutz, Sharon M, Cho, Michael H, Broome, Jai, Khan, Alyna T, Wang, Fei Fei, Heard-Costa, Nancy, Seshadri, Sudha, Vasan, Ramachandran S, Palmer, Nicholette D, Freedman, Barry I, Bowden, Donald W, Yanek, Lisa R, Kral, Brian G, Becker, Lewis C, Peyser, Patricia A, Bielak, Lawrence F, Ammous, Farah, Carson, April P, Hall, Michael E, Raffield, Laura M, Rich, Stephen S, Post, Wendy S, Tracy, Russel P, Taylor, Kent D, Guo, Xiuqing, Mahaney, Michael C, Curran, Joanne E, Blangero, John, Clarke, Shoa L, Haessler, Jeffrey W, Hu, Yao, Assimes, Themistocles L, Kooperberg, Charles, Bernhagen, Jürgen, Anderson, Christopher D, Damrauer, Scott M, Zand, Ramin, Rotter, Jerome I, de Vries, Paul S, Dichgans, Martin
Published in medRxiv : the preprint server for health sciences (26.06.2024)
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Published in medRxiv : the preprint server for health sciences (26.06.2024)
Journal Article
Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People with Type 2 Diabetes Mellitus
Kwak, Soo Heon, Hernandez-Cancela, Ryan B, DiCorpo, Daniel A, Condon, David E, Merino, Jordi, Wu, Peitao, Brody, Jennifer A, Yao, Jie, Guo, Xiuqing, Ahmadizar, Fariba, Meyer, Mariah, Sincan, Murat, Mercader, Josep M, Lee, Sujin, Haessler, Jeffrey, Vy, Ha My T, Lin, Zhaotong, Armstrong, Nicole D, Gu, Shaopeng, Tsao, Noah L, Lange, Leslie A, Wang, Ningyuan, Wiggins, Kerri L, Trompet, Stella, Liu, Simin, Loos, Ruth J F, Judy, Renae, Schroeder, Philip H, Hasbani, Natalie R, Bos, Maxime M, Morrison, Alanna C, Jackson, Rebecca D, Reiner, Alexander P, Manson, JoAnn E, Chaudhary, Ninad S, Carmichael, Lynn K, Chen, Yii-Der Ida, Taylor, Kent D, Ghanbari, Mohsen, van Meurs, Joyce, Pitsillides, Achilleas N, Psaty, Bruce M, Noordam, Raymond, Do, Ron, Park, Kyong Soo, Jukema, J Wouter, Kavousi, Maryam, Correa, Adolfo, Rich, Stephen S, Damrauer, Scott M, Hajek, Catherine, Cho, Nam H, Irvin, Marguerite R, Pankow, James S, Nadkarni, Girish N, Sladek, Robert, Goodarzi, Mark O, Florez, Jose C, Chasman, Daniel I, Heckbert, Susan R, Kooperberg, Charles, Dupuis, Josée, Malhotra, Rajeev, de Vries, Paul S, Liu, Ching-Ti, Rotter, Jerome I, Meigs, James B
Published in medRxiv : the preprint server for health sciences (28.07.2023)
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Published in medRxiv : the preprint server for health sciences (28.07.2023)
Journal Article
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
Judd, Jonathan, Graham, Sarah E, Wells, Andrew, Hilliard, Austin T, Xue, Chao, Helgadottir, Anna, Holm, Hilma, Han, Sohee, Sakaue, Saori, Jennifer Allen Pacheco, Feng, Qiping, Lin, Kuang, Zhao, Wei, Brown, Michael R, Yin, Xianyong, Luan, Jian'an, Jing-Hua, Zhao, Hye-Mi Jang, Hottenga, Jouke Jan, Haworth, Simon, Wielscher, Matthias, Sattar, Naveed, Munz, Matthias, Yang, Bin, Zmuda, Joseph M, Feitosa, Mary F, Benjamins, Jan W, Delgado, Graciela E, Fernandez-Lopez, Juan Carlos, Timmers, Paul Rhj, Arbeeva, Liubov, Spracklen, Cassandra N, Loukola, Anu, Ya Xing Wang, Nutile, Teresa, Sung, Yun Ju, Kentistou, Katherine A, Bielak, Lawrence F, Peter J Van Der Most, Sander W Van Der Laan, Kumaraswamy Naidu Chitrala, Freitag-Wolf, Sandra, Southam, Lorraine, Wang, Carol A, Shih-Yi, Lin, Terzikhan, Natalie, Kawaguchi, Takahisa, Campbell, Harry, Niinikoski, Harri, Eung Kweon Kim, Hewitt, Alex W, Kahonen, Mika, Pennell, Craig E, Franke, Andre, Koh, Woon-Puay, Jeong-Taek Woo, Biino, Ginevra, Dedoussis, George, Schulze, Matthias B, Munroe, Patricia B, Jonas, Jost B, De Silva, H Janaka, Wu, Jer-Yuarn, Den Hollander, Anneke I, Bharadwaj, Dwaipayan, Wilson, James G, Orozco, Lorena, nage, Myriam, Reilly, Dermot F, Lu, Fan, Hishigaki, Haretsugu, Gudnason, Vilmundur, Tardif, Jean-Claude, Hart, Leen M T, Loos, Ruth Jf, Christensen, Kaare, Kronenberg, Florian, Kutalik, Zoltan, Rotter, Jerome I, Neville, Matt J, Tien-Yin, Wong, Khor, Chiea Chuen, Li, Hengtong, Hattersley, Andrew T, Gordon-Larsen, Penny, Huang, Wei, Tuomilehto, Jaakko, Ingelsson, Erik, Hazelhurst, Scott, Saleheen, Danish, Kooperberg, Charles, Tamiya, Gen, Van Heel, David A, Jarvik, Gail P, Salomaa, Veikko, Murakami, Yoshinori, Zhang, Jifeng, Lynch, Julie A, Grant, Struan Fa, Morris, Andrew P
Published in bioRxiv (08.12.2021)
Published in bioRxiv (08.12.2021)
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