Cannabinoid 1 and mu-Opioid Receptor Agonists Synergistically Inhibit Abdominal Pain and Lack Side Effects in Mice
Yu, Yang, Tsang, Quentin K, Jaramillo-Polanco, Josue, Lomax, Alan E, Vanner, Stephen J, Reed, David E
Published in The Journal of neuroscience (17.08.2022)
Published in The Journal of neuroscience (17.08.2022)
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322 CANNABINOID 1 RECEPTOR SIGNALING IN COLONIC NOCICPETION IS ALTERED BY CHANGES OF THE ENDOCANNABINOID SYSTEM DURING COLITIS
Tsang, Quentin K., Kaufmann, Martin, Lomax, Alan E., Vanner, Stephen, Reed, David E.
Published in Gastroenterology (New York, N.Y. 1943) (18.05.2024)
Published in Gastroenterology (New York, N.Y. 1943) (18.05.2024)
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Sa1757 CANNABINOID AND OPIOID RECEPTOR SIGNALING IN COLONIC NOCICEPTORS IS MARKEDLY ALTERED BY ACUTE COLITIS
Tsang, Quentin K., Schincariol, Hailey M., Degro, Claudius E., Lomax, Alan E., Vanner, Stephen, Reed, David E.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2023)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2023)
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Sa1232 NOVEL PH-SENSITIVE OPIOID DOES NOT INDUCE TOLERANCE IN A COLITIS MOUSE MODEL
Jiménez-Vargas, Nestor N., Degro, Claudius E., Tsang, Quentin K., Guzman-Rodriguez, Mabel, Lomax, Alan E., Reed, David E., Stein, Christoph, Bunnett, Nigel W., Vanner, Stephen
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2023)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2023)
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Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects
Jiménez-Vargas, Nestor Nivardo, Yu, Yang, Jensen, Dane D, Bok, Diana Daeun, Wisdom, Matthew, Latorre, Rocco, Lopez, Cintya, Jaramillo-Polanco, Josue O, Degro, Claudius, Guzman-Rodriguez, Mabel, Tsang, Quentin, Snow, Zachary, Schmidt, Brian L, Reed, David E, Lomax, Alan Edward, Margolis, Kara Gross, Stein, Christoph, Bunnett, Nigel W, Vanner, Stephen J
Published in Gut (01.04.2022)
Published in Gut (01.04.2022)
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242: A NOVEL PH-SENSITIVE OPIOID PROVIDES SUSTAINED ANALGESIA DURING COLONIC INFLAMMATION AND LACKS COMMON SIDE EFFECTS
Jiménez-Vargas, Nestor N., Degro, Claudius E., Tsang, Quentin K., Yu, Yang, Stein, Christoph, Bunnett, Nigel W., Lomax, Alan E., Reed, David E., Vanner, Stephen
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
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A pH-sensitive opioid does not exhibit analgesic tolerance in a mouse model of colonic inflammation
Degro, Claudius E, Jiménez-Vargas, Nestor Nivardo, Guzman-Rodriguez, Mabel, Schincariol, Hailey, Tsang, Quentin, Reed, David E, Lomax, Alan E, Bunnett, Nigel W, Stein, Christoph, Vanner, Stephen J
Published in British journal of pharmacology (13.10.2024)
Published in British journal of pharmacology (13.10.2024)
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675 A NOVEL PH-SENSITIVE OPIOID ANALGESIC THAT SELECTIVELY INHIBITS COLONIC INFLAMMATORY PAIN
Jiménez-Vargas, Nestor N., Yu, Yang, Tsang, Quentin, Guzman-Rodriguez, Mabel, Degro, Claudius E., Stein, Christoph, Lomax, Alan E., Reed, David E., Bunnett, Nigel W., Vanner, Stephen
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
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Evolving acidic microenvironments during colitis provide selective analgesic targets for a pH-sensitive opioid
Degro, Claudius E, Jiménez-Vargas, Nestor Nivardo, Tsang, Quentin, Yu, Yang, Guzman-Rodriguez, Mabel, Alizadeh, Elahe, Hurlbut, David, Reed, David E, Lomax, Alan E, Stein, Christoph, Bunnett, Nigel W, Vanner, Stephen J
Published in Pain (Amsterdam) (01.11.2023)
Published in Pain (Amsterdam) (01.11.2023)
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Changes in signalling from faecal neuroactive metabolites following dietary modulation of IBS pain
Tuck, Caroline J, Abu Omar, Amal, De Palma, Giada, Osman, Samira, Jiménez-Vargas, Nestor N, Yu, Yang, Bennet, Sean MP, Lopez-Lopez, Cintya, Jaramillo-Polanco, Josue O, Baker, Corey C, Bennett, Aidan SW, Guzman-Rodriguez, Mabel, Tsang, Quentin, Alward, Taylor, Rolland, Sebastien, Morissette, Celine, Verdu, Elena F, Bercik, Premysl, Vanner, Stephen J, Lomax, Alan E, Reed, David E
Published in Gut (01.09.2023)
Published in Gut (01.09.2023)
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Protease-Induced Excitation of Dorsal Root Ganglion Neurons in Response to Acute Perturbation of the Gut Microbiota is Associated with Visceral Hypersensitivity
Baker, Corey C, Sessenwein, Jessica, Omar, Amal A, Tsang, Quentin, Yu, Yang, Segal, Julia, Ghasemlou, Nader, Sheth, Prameet, Vanner, Stephen, Reed, David, Lomax, Alan
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Dietary monosodium glutamate increases visceral hypersensitivity in a mouse model of visceral pain
Brant, Bailey J. A., Yu, Yang, Omar, Amal Abu, Jaramillo Polanco, Josue O., Lopez Lopez, Cintya D., Jiménez Vargas, Nestor N., Tsang, Quentin, McDonell, Abby, Takami, Kaede, Reed, David E., Lomax, Alan E., Vanner, Stephen J., Tuck, Caroline J.
Published in Neurogastroenterology and motility (01.09.2023)
Published in Neurogastroenterology and motility (01.09.2023)
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Protease-Induced Excitation of Dorsal Root Ganglion Neurons in Response to Acute Perturbation of the Gut Microbiota Is Associated With Visceral and Somatic Hypersensitivity
Baker, Corey C., Sessenwein, Jessica L., Wood, Hannah M., Yu, Yang, Tsang, Quentin, Alward, Taylor A., Jimenez Vargas, Nestor N., Omar, Amal Abu, McDonnel, Abby, Segal, Julia P., Sjaarda, Calvin P., Bunnett, Nigel W., Schmidt, Brian L., Caminero, Alberto, Boev, Nadejda, Bannerman, Courtney A., Ghasemlou, Nader, Sheth, Prameet M., Vanner, Stephen J., Reed, David E., Lomax, Alan E.
Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
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