The GDF15-GFRAL Pathway in Health and Metabolic Disease: Friend or Foe?
Breit, Samuel N, Brown, David A, Tsai, Vicky Wang-Wei
Published in Annual review of physiology (10.02.2021)
Published in Annual review of physiology (10.02.2021)
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Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets
Macia, Laurence, Tsai, Vicky Wang-Wei, Nguyen, Amy D, Johnen, Heiko, Kuffner, Tamara, Shi, Yan-Chuan, Lin, Shu, Herzog, Herbert, Brown, David A, Breit, Samuel N, Sainsbury, Amanda
Published in PloS one (13.04.2012)
Published in PloS one (13.04.2012)
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The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract
Tsai, Vicky Wang-Wei, Manandhar, Rakesh, Jørgensen, Sebastian Beck, Lee-Ng, Ka Ki Michelle, Zhang, Hong Ping, Marquis, Christopher Peter, Jiang, Lele, Husaini, Yasmin, Lin, Shu, Sainsbury, Amanda, Sawchenko, Paul E, Brown, David A, Breit, Samuel N
Published in PloS one (27.06.2014)
Published in PloS one (27.06.2014)
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Growth differentiation factor-15 slows the growth of murine prostate cancer by stimulating tumor immunity
Husaini, Yasmin, Tsai, Vicky Wang-Wei, Manandhar, Rakesh, Zhang, Hong Ping, Lee-Ng, Ka Ki Michelle, Lebhar, Hélène, Marquis, Christopher P, Brown, David A, Breit, Samuel N, Saleem, MOHAMMAD
Published in PloS one (05.06.2020)
Published in PloS one (05.06.2020)
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GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS
Tsai, Vicky Wang-Wei, Zhang, Hong Ping, Manandhar, Rakesh, Schofield, Peter, Christ, Daniel, Lee-Ng, Ka Ki Michelle, Lebhar, Hélène, Marquis, Christopher Peter, Husaini, Yasmin, Brown, David A., Breit, Samuel N.
Published in International Journal of Obesity (01.12.2019)
Published in International Journal of Obesity (01.12.2019)
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Stream type influences food abundance and reproductive performance of a stream specialist: the Brown Dipper (Cinclus pallasii)
Hong, Shiao-Yu, Wang, Tsai-Wei, Sun, Yuan-Hsun, Chiu, Ming-Chih, Kuo, Mei-Hwa, Chen, Chao-Chieh
Published in Journal of ornithology (01.01.2019)
Published in Journal of ornithology (01.01.2019)
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Macrophage inhibitory cytokine-1 (MIC-1/GDF15) slows cancer development but increases metastases in TRAMP prostate cancer prone mice
Husaini, Yasmin, Qiu, Min Ru, Lockwood, Glen P, Luo, Xu Wei, Shang, Ping, Kuffner, Tamara, Tsai, Vicky Wang-Wei, Jiang, Lele, Russell, Pamela J, Brown, David A, Breit, Samuel N
Published in PloS one (27.08.2012)
Published in PloS one (27.08.2012)
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Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease
BREIT, Samuel N, CARRERO, Juan J, HEIMBURGER, Olof, MURIKAMI, Mary-Ann, APPLE, Fred S, MARQUIS, Christopher P, MACIA, Laurence, SHU LIN, SAINSBURY, Amanda, HERZOG, Herbert, LAW, Matthew, STENVINKEL, Peter, WANG-WEI TSAI, Vicky, BROWN, David A, YAGOUTIFAM, Nasreen, WEI LUO, KUFFNER, Tamara, BAUSKIN, Asne R, LIYUN WU, LELE JIANG, BARANY, Peter
Published in Nephrology, dialysis, transplantation (01.01.2012)
Published in Nephrology, dialysis, transplantation (01.01.2012)
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Macrophage inhibitory cytokine-1 (MIC-1/GDF15) gene deletion promotes cancer growth in TRAMP prostate cancer prone mice
Husaini, Yasmin, Lockwood, Glen P, Nguyen, Trung V, Tsai, Vicky Wang-Wei, Mohammad, Mohammad G, Russell, Pamela J, Brown, David A, Breit, Samuel N
Published in PloS one (19.02.2015)
Published in PloS one (19.02.2015)
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TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator
Tsai, Vicky Wang-Wei, Macia, Laurence, Johnen, Heiko, Kuffner, Tamara, Manadhar, Rakesh, Jørgensen, Sebastian Beck, Lee-Ng, Ka Ki Michelle, Zhang, Hong Ping, Wu, Liyun, Marquis, Christopher Peter, Jiang, Lele, Husaini, Yasmin, Lin, Shu, Herzog, Herbert, Brown, David A, Sainsbury, Amanda, Breit, Samuel N
Published in PloS one (28.02.2013)
Published in PloS one (28.02.2013)
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Primary Care Engagement Among Individuals with Experiences of Homelessness and Serious Mental Illness: an Evidence Map
Shepherd-Banigan, Megan, Drake, Connor, Dietch, Jessica R., Shapiro, Abigail, Tabriz, Amir Alishahi, Van Voorhees, Elizabeth E., Uthappa, Diya M., Wang, Tsai-Wei, Lusk, Jay B., Rossitch, Stephanie Salcedo, Fulton, Jessica, Gordon, Adelaide, Ear, Belinda, Cantrell, Sarah, Gierisch, Jennifer M., Williams, John W., Goldstein, Karen M.
Published in Journal of general internal medicine : JGIM (01.05.2022)
Published in Journal of general internal medicine : JGIM (01.05.2022)
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Targeting Obesity and Cachexia: Identification of the GFRAL Receptor–MIC-1/GDF15 Pathway
Breit, Samuel N., Tsai, Vicky Wang-Wei, Brown, David A.
Published in Trends in molecular medicine (01.12.2017)
Published in Trends in molecular medicine (01.12.2017)
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Patients’ Experiences With Staphylococcus aureus and Gram-Negative Bacterial Bloodstream Infections: Results From Cognitive Interviews to Inform Assessment of Health-Related Quality of Life
King, Heather A, Doernberg, Sarah B, Grover, Kiran, Miller, Julie, Oakes, Megan, Wang, Tsai-Wei, McFatrich, Molly, Ruffin, Felicia, Staman, Karen, Lane, Hannah G, Rader, Abigail, Sund, Zoë, Bosworth, Hayden B, Reeve, Bryce B, Fowler, Vance G, Holland, Thomas L
Published in Open forum infectious diseases (01.02.2022)
Published in Open forum infectious diseases (01.02.2022)
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β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling
Thai, Le May, O’Reilly, Liam, Reibe-Pal, Saskia, Sue, Nancy, Holliday, Holly, Small, Lewin, Schmitz-Peiffer, Carsten, Dhenni, Rama, Wang-Wei Tsai, Vicky, Norris, Nicholas, Yau, Belinda, Zhang, Xuan, Lee, Kailun, Yan, Chenxu, Shi, Yan-Chuan, Kebede, Melkam A., Brink, Robert, Cooney, Gregory J., Irvine, Katharine M., Breit, Samuel N., Phan, Tri G., Swarbrick, Alexander, Biden, Trevor J.
Published in iScience (21.04.2023)
Published in iScience (21.04.2023)
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Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin
Kuo, Lan-Hsin, Hu, Ming-Kuan, Hsu, Wen-Ming, Tung, Ying-Tsen, Wang, Bo-Jeng, Tsai, Wang-Wei, Yen, Chen-Tung, Liao, Yung-Feng
Published in Molecular biology of the cell (01.10.2008)
Published in Molecular biology of the cell (01.10.2008)
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Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1
Junankar, Simon, Lin, Shu, Corey, Eva, Johnen, Heiko, Pankhurst, Greg, Kuffner, Tamara, Tsai, Vicky Wang-Wei, Baldock, Paul A, Herzog, Herbert, Wu, Liyun, Jiang, Lele, Lee, Nicola J, Enriquez, Ronaldo F, Bauskin, Asne R, Lin, En-Ju, Hunter, Mark, Breit, Samuel N, Fairlie, W Douglas, Murakami, MaryAnn M, During, Matthew J, Sainsbury, Amanda, Wang, Chuansong, Brown, David A, Apple, Fred S
Published in Nature medicine (01.11.2007)
Published in Nature medicine (01.11.2007)
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Intracellular chloride channel protein CLIC1 regulates macrophage function through modulation of phagosomal acidification
Jiang, Lele, Salao, Kanin, Li, Hui, Rybicka, Joanna M, Yates, Robin M, Luo, Xu Wei, Shi, Xin Xin, Kuffner, Tamara, Tsai, Vicky Wang-Wei, Husaini, Yasmin, Wu, Liyun, Brown, David A, Grewal, Thomas, Brown, Louise J, Curmi, Paul M G, Breit, Samuel N
Published in Journal of cell science (15.11.2012)
Published in Journal of cell science (15.11.2012)
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The evaluation of 2,8-disubstituted benzoxazinone derivatives as anti-inflammatory and anti-platelet aggregation agents
Hsieh, Pei-Wen, Hwang, Tsong-Long, Wu, Chin-Chung, Chang, Fang-Rong, Wang, Tsai-Wei, Wu, Yang-Chang
Published in Bioorganic & medicinal chemistry letters (02.06.2005)
Published in Bioorganic & medicinal chemistry letters (02.06.2005)
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