Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation
Lee, Joo-Hyung, Wang, Ruoyu, Xiong, Feng, Krakowiak, Joanna, Liao, Zian, Nguyen, Phuoc T., Moroz-Omori, Elena V., Shao, Jiaofang, Zhu, Xiaoyu, Bolt, Michael J., Wu, Haoyi, Singh, Pankaj K., Bi, Mingjun, Shi, Caleb J., Jamal, Naadir, Li, Guojie, Mistry, Ragini, Jung, Sung Yun, Tsai, Kuang-Lei, Ferreon, Josephine C., Stossi, Fabio, Caflisch, Amedeo, Liu, Zhijie, Mancini, Michael A., Li, Wenbo
Published in Molecular cell (19.08.2021)
Published in Molecular cell (19.08.2021)
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Journal Article
Subunit architecture and functional modular rearrangements of the transcriptional mediator complex
Tsai, Kuang-Lei, Tomomori-Sato, Chieri, Sato, Shigeo, Conaway, Ronald C, Conaway, Joan W, Asturias, Francisco J
Published in Cell (05.06.2014)
Published in Cell (05.06.2014)
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Journal Article
Mediator structure and rearrangements required for holoenzyme formation
Tsai, Kuang-Lei, Yu, Xiaodi, Gopalan, Sneha, Chao, Ti-Chun, Zhang, Ying, Florens, Laurence, Washburn, Michael P., Murakami, Kenji, Conaway, Ronald C., Conaway, Joan W., Asturias, Francisco J.
Published in Nature (London) (13.04.2017)
Published in Nature (London) (13.04.2017)
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Journal Article
A noncoding RNA modulator potentiates phenylalanine metabolism in mice
Li, Yajuan, Tan, Zhi, Zhang, Yaohua, Zhang, Zhao, Hu, Qingsong, Liang, Ke, Jun, Yao, Ye, Youqiong, Li, Yi-Chuan, Li, Chunlai, Liao, Lan, Xu, Jianming, Xing, Zhen, Pan, Yinghong, Chatterjee, Sujash S, Nguyen, Tina K, Hsiao, Heidi, Egranov, Sergey D, Putluri, Nagireddy, Coarfa, Cristian, Hawke, David H, Gunaratne, Preethi H, Tsai, Kuang-Lei, Han, Leng, Hung, Mien-Chie, Calin, George A, Namour, Fares, Guéant, Jean-Louis, Muntau, Ania C, Blau, Nenad, Sutton, V Reid, Schiff, Manuel, Feillet, François, Zhang, Shuxing, Lin, Chunru, Yang, Liuqing
Published in Science (American Association for the Advancement of Science) (06.08.2021)
Published in Science (American Association for the Advancement of Science) (06.08.2021)
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Journal Article
3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound
Brignole, Edward J, Tsai, Kuang-Lei, Chittuluru, Johnathan, Li, Haoran, Aye, Yimon, Penczek, Pawel A, Stubbe, JoAnne, Drennan, Catherine L, Asturias, Francisco
Published in eLife (20.02.2018)
Published in eLife (20.02.2018)
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Journal Article
The Hypoxia-Adenosine Link during Myocardial Ischemia-Reperfusion Injury
Ruan, Wei, Ma, Xinxin, Bang, In Hyuk, Liang, Yafen, Muehlschlegel, Jochen Daniel, Tsai, Kuang-Lei, Mills, Tingting W, Yuan, Xiaoyi, Eltzschig, Holger K
Published in Biomedicines (01.08.2022)
Published in Biomedicines (01.08.2022)
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Journal Article
crystal structure of a replicative hexameric helicase DnaC and its complex with single-stranded DNA
Lo, Yu-Hua, Tsai, Kuang-Lei, Sun, Yuh-Ju, Chen, Wei-Ti, Huang, Cheng-Yang, Hsiao, Chwan-Deng
Published in Nucleic acids research (01.02.2009)
Published in Nucleic acids research (01.02.2009)
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Journal Article
Crystal Structure of the Human FOXK1a-DNA Complex and Its Implications on the Diverse Binding Specificity of Winged Helix/Forkhead Proteins
Tsai, Kuang-Lei, Huang, Cheng-Yang, Chang, Chia-Hao, Sun, Yuh-Ju, Chuang, Woei-Jer, Hsiao, Chwan-Deng
Published in The Journal of biological chemistry (23.06.2006)
Published in The Journal of biological chemistry (23.06.2006)
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Journal Article
Structure of a designed protein cage that self-assembles into a highly porous cube
Lai, Yen-Ting, Reading, Eamonn, Hura, Greg L., Tsai, Kuang-Lei, Laganowsky, Arthur, Asturias, Francisco J., Tainer, John A., Robinson, Carol V., Yeates, Todd O.
Published in Nature chemistry (01.12.2014)
Published in Nature chemistry (01.12.2014)
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Journal Article
A conserved Mediator–CDK8 kinase module association regulates Mediator–RNA polymerase II interaction
Tsai, Kuang-Lei, Sato, Shigeo, Tomomori-Sato, Chieri, Conaway, Ronald C, Conaway, Joan W, Asturias, Francisco J
Published in Nature structural & molecular biology (01.05.2013)
Published in Nature structural & molecular biology (01.05.2013)
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Journal Article
Comparative parallel analysis of RNA ends identifies mRNA substrates of a tRNA splicing endonuclease-initiated mRNA decay pathway
Hurtig, Jennifer E., Steiger, Michelle A., Nagarajan, Vinay K., Li, Tao, Chao, Ti-Chun, Tsai, Kuang-Lei, van Hoof, Ambro
Published in Proceedings of the National Academy of Sciences - PNAS (09.03.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (09.03.2021)
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Journal Article
Structural basis of a transcription pre-initiation complex on a divergent promoter
Gorbea Colón, Jose J., Palao, Leon, Chen, Shin-Fu, Kim, Hee Jong, Snyder, Laura, Chang, Yi-Wei, Tsai, Kuang-Lei, Murakami, Kenji
Published in Molecular cell (16.02.2023)
Published in Molecular cell (16.02.2023)
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Journal Article
Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies
Tu, Jian, Huo, Zijun, Yu, Yao, Zhu, Dandan, Xu, An, Huang, Mo-Fan, Hu, Ruifeng, Wang, Ruoyu, Gingold, Julian A, Chen, Yi-Hung, Tsai, Kuang-Lei, Forcioli-Conti, Nicolas R, Huang, Sarah X L, Webb, Thomas R, Su, Jie, Bazer, Danielle A, Jia, Peilin, Yustein, Jason T, Wang, Lisa L, Hung, Mien-Chie, Zhao, Zhongming, Huff, Chad D, Shen, Jingnan, Zhao, Ruiying, Lee, Dung-Fang
Published in Proceedings of the National Academy of Sciences - PNAS (19.04.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (19.04.2022)
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Journal Article
Reconstitution of the augmin complex provides insights into its architecture and function
Hsia, Kuo-Chiang, Wilson-Kubalek, Elizabeth M., Dottore, Alejandro, Hao, Qi, Tsai, Kuang-Lei, Forth, Scott, Shimamoto, Yuta, Milligan, Ronald A., Kapoor, Tarun M.
Published in Nature cell biology (01.09.2014)
Published in Nature cell biology (01.09.2014)
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Journal Article
Architecture of the Mediator head module
Imasaki, Tsuyoshi, Calero, Guillermo, Cai, Gang, Tsai, Kuang-Lei, Yamada, Kentaro, Cardelli, Francesco, Erdjument-Bromage, Hediye, Tempst, Paul, Berger, Imre, Kornberg, Guy Lorch, Asturias, Francisco J., Kornberg, Roger D., Takagi, Yuichiro
Published in Nature (London) (14.07.2011)
Published in Nature (London) (14.07.2011)
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