Studies Directed toward Asymmetric Synthesis of Cardioactive Steroids via Anionic Polycyclization
Yang, Zhixiang, Shannon, Dean, Truong, Vouy-Linh, Deslongchamps, Pierre
Published in Organic letters (26.12.2002)
Published in Organic letters (26.12.2002)
Get full text
Journal Article
Simplified assays of lipolysis enzymes for drug discovery and specificity assessment of known inhibitors
Iglesias, Jose, Lamontagne, Julien, Erb, Heidi, Gezzar, Sari, Zhao, Shangang, Joly, Erik, Truong, Vouy Linh, Skorey, Kathryn, Crane, Sheldon, Madiraju, S.R.Murthy, Prentki, Marc
Published in Journal of lipid research (01.01.2016)
Published in Journal of lipid research (01.01.2016)
Get full text
Journal Article
The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K
Gauthier, Jacques Yves, Chauret, Nathalie, Cromlish, Wanda, Desmarais, Sylvie, Duong, Le T., Falgueyret, Jean-Pierre, Kimmel, Donald B., Lamontagne, Sonia, Léger, Serge, LeRiche, Tammy, Li, Chun Sing, Massé, Frédéric, McKay, Daniel J., Nicoll-Griffith, Deborah A., Oballa, Renata M., Palmer, James T., Percival, M. David, Riendeau, Denis, Robichaud, Joel, Rodan, Gideon A., Rodan, Sevgi B., Seto, Carmai, Thérien, Michel, Truong, Vouy-Linh, Venuti, Michael C., Wesolowski, Gregg, Young, Robert N., Zamboni, Robert, Black, W. Cameron
Published in Bioorganic & medicinal chemistry (01.02.2008)
Published in Bioorganic & medicinal chemistry (01.02.2008)
Get full text
Journal Article
Synthesis of a novel peptidic photoaffinity probe for the PTP-1B enzyme
THERIEN, Michel, SKOREY, Kathryn, ZAMBONI, Robert, CHUN SING LI, LAU, Cheuk K, LERICHE, Tammy, VOUY LINH TRUONG, WADDLETON, Deena, RAMACHANDRAN, Chidambaram
Published in Bioorganic & medicinal chemistry letters (03.05.2004)
Published in Bioorganic & medicinal chemistry letters (03.05.2004)
Get full text
Journal Article
Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group
Bungard, Christopher J, Williams, Peter D, Ballard, Jeanine E, Bennett, David J, Beaulieu, Christian, Bahnck-Teets, Carolyn, Carroll, Steve S, Chang, Ronald K, Dubost, David C, Fay, John F, Diamond, Tracy L, Greshock, Thomas J, Hao, Li, Holloway, M. Katharine, Felock, Peter J, Gesell, Jennifer J, Su, Hua-Poo, Manikowski, Jesse J, McKay, Daniel J, Miller, Mike, Min, Xu, Molinaro, Carmela, Moradei, Oscar M, Nantermet, Philippe G, Nadeau, Christian, Sanchez, Rosa I, Satyanarayana, Tummanapalli, Shipe, William D, Singh, Sanjay K, Truong, Vouy Linh, Vijayasaradhi, Sivalenka, Wiscount, Catherine M, Vacca, Joseph P, Crane, Sheldon N, McCauley, John A
Published in ACS medicinal chemistry letters (14.07.2016)
Published in ACS medicinal chemistry letters (14.07.2016)
Get full text
Journal Article
Synthesis and SAR of pyrimidine-based, non-nucleotide P2Y₁₄ receptor antagonists
Guay, Daniel, Beaulieu, Christian, Belley, Michel, Crane, Sheldon N, DeLuca, Jeancarlo, Gareau, Yves, Hamel, Martine, Henault, Martin, Hyjazie, Huda, Kargman, Stacia, Chan, Chi Chung, Xu, Lijing, Gordon, Robert, Li, Lianhai, Mamane, Yael, Morin, Nicolas, Mancini, Joseph, Thérien, Michel, Tranmer, Geoffrey, Truong, Vouy Linh, Wang, Zhaoyin, Black, W. Cameron
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Get full text
Journal Article
The identification of potent, selective, and bioavailable cathepsin S inhibitors
Gauthier, Jacques Yves, Black, W. Cameron, Courchesne, Isabelle, Cromlish, Wanda, Desmarais, Sylvie, Houle, Robert, Lamontagne, Sonia, Li, Chun Sing, Massé, Frédéric, McKay, Daniel J., Ouellet, Marc, Robichaud, Joël, Truchon, Jean-François, Truong, Vouy-Linh, Wang, Qingping, Percival, M. David
Published in Bioorganic & medicinal chemistry letters (01.09.2007)
Published in Bioorganic & medicinal chemistry letters (01.09.2007)
Get full text
Journal Article
Identification of a potent and selective non-basic cathepsin K inhibitor
Li, Chun Sing, Deschenes, Denis, Desmarais, Sylvie, Falgueyret, Jean-Pierre, Gauthier, Jacques Yves, Kimmel, Donald. B., Léger, Serge, Massé, Frédéric, McGrath, Mary E., McKay, Daniel J., Percival, M. David, Riendeau, Denis, Rodan, Sevgi B., Thérien, Michel, Truong, Vouy-Linh, Wesolowski, Gregg, Zamboni, Robert, Black, W. Cameron
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Get full text
Journal Article
Difluoroethylamines as an amide isostere in inhibitors of cathepsin K
Isabel, Elise, Mellon, Christophe, Boyd, Michael J., Chauret, Nathalie, Deschênes, Denis, Desmarais, Sylvie, Falgueyret, Jean-Pierre, Gauthier, Jacques Yves, Khougaz, Karine, Lau, Cheuk K., Léger, Serge, Levorse, Dorothy A., Li, Chun Sing, Massé, Frédéric, David Percival, M., Roy, Bruno, Scheigetz, John, Thérien, Michel, Truong, Vouy Linh, Wesolowski, Gregg, Young, Robert N., Zamboni, Robert, Cameron Black, W.
Published in Bioorganic & medicinal chemistry letters (01.02.2011)
Published in Bioorganic & medicinal chemistry letters (01.02.2011)
Get full text
Journal Article
Selective isolation of in vitro phase II conjugates using a lipophilic anionic exchange solid phase extraction method
Gagné, Sébastien, Laterreur, Julie, Mahrouche, Louiza, Sørensen, Dan, Gauthier, Jacques Yves, Truong, Vouy Linh, Chauret, Nathalie, Lévesque, Jean-François
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.03.2008)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.03.2008)
Get full text
Journal Article
화합물, 약제 조성물, 및 화합물 제조 방법 및 ATR 키나제 억제제로서의 이것들의 사용 방법
ABDOLI ABBAS, DORICH STEPHANE, FADER LEE, PICARD AUDREY, LACBAY CYRUS M, JONES PAUL, TRUONG VOUY LINH, BLACK CAMERON, ST ONGE MIGUEL, CRANE SHELDON N, TRUCHON JEAN FRANCOIS, LANOIX STEPHANIE
Year of Publication 06.08.2021
Get full text
Year of Publication 06.08.2021
Patent
SMALL MOLECULE MODULATORS OF PCSK9 AND METHODS OF USE THEREOF
SKOREY KATHRYN, CRANE SHELDON, GUAY DANIEL, SEIDAH NABIL G, TRUONG VOUY LINH, LACOMBE PATRICK, LACHANCE NICOLAS, CHIASSON JEAN FRANCOIS
Year of Publication 25.11.2015
Get full text
Year of Publication 25.11.2015
Patent
Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500)
Black, W. Cameron, Abdoli, Abbas, An, Xiuli, Auger, Anick, Beaulieu, Patrick, Bernatchez, Michel, Caron, Cathy, Chefson, Amandine, Crane, Sheldon, Diallo, Mohamed, Dorich, Stéphane, Fader, Lee D., Ferraro, Gino B., Fournier, Sara, Gao, Qi, Ginzburg, Yelena, Hamel, Martine, Han, Yongshuai, Jones, Paul, Lanoix, Stéphanie, Lacbay, Cyrus M., Leclaire, Marie-Eve, Levy, Maayan, Mamane, Yael, Mulani, Amina, Papp, Robert, Pellerin, Charles, Picard, Audrey, Skeldon, Alexander, Skorey, Kathryn, Stocco, Rino, St.-Onge, Miguel, Truchon, Jean-François, Truong, Vouy Linh, Zimmermann, Michal, Zinda, Michael, Roulston, Anne
Published in Journal of medicinal chemistry (22.02.2024)
Published in Journal of medicinal chemistry (22.02.2024)
Get full text
Journal Article
HIV PROTEASE INHIBITORS
SHIPE WILLIAM, MORADEI OSCAR MIGUEL, GRESHOCK THOMAS J, WILLIAMS PETER D, MCKAY DANIEL, BENNETT DAVID J, MANIKOWSKI JESSE J, CHANG RONALD K, SATYANARAYANA TUMMANAPALLI, HOLLOWAY KATE, VIJAYASARADHI SIVALENKA, CRANE SHELDON, BEAULIEU CHRISTIAN, NANTERMET PHILIPPE G, MOLINARO CARMELA, BUNGARD CHRISTOPHER J, TRUONG VOUY LINH, MCCAULEY JOHN A, HAO LI, SINGH SANJAY KUMAR, WISCOUNT CATHERINE M, NADEAU CHRISTIAN
Year of Publication 19.05.2015
Get full text
Year of Publication 19.05.2015
Patent
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases
Gallant, Michel, Beaulieu, Christian, Berthelette, Carl, Colucci, John, Crackower, Michael A., Dalton, Chad, Denis, Danielle, Ducharme, Yves, Friesen, Richard W., Guay, Daniel, Gervais, François G., Hamel, Martine, Houle, Robert, Krawczyk, Connie M., Kosjek, Birgit, Lau, Stephen, Leblanc, Yves, Lee, Ernest E., Levesque, Jean-François, Mellon, Christophe, Molinaro, Carmela, Mullet, Wayne, O’Neill, Gary P., O’Shea, Paul, Sawyer, Nicole, Sillaots, Susan, Simard, Daniel, Slipetz, Deborah, Stocco, Rino, Sørensen, Dan, Truong, Vouy Linh, Wong, Elizabeth, Wu, Jin, Zaghdane, Helmi, Wang, Zhaoyin
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Get full text
Journal Article
The discovery of MK-0674, an orally bioavailable cathepsin K inhibitor
Isabel, Elise, Bateman, Kevin P., Chauret, Nathalie, Cromlish, Wanda, Desmarais, Sylvie, Duong, Le T., Falgueyret, Jean-Pierre, Gauthier, Jacques Yves, Lamontagne, Sonia, Lau, Cheuk K., Léger, Serge, LeRiche, Tammy, Lévesque, Jean-François, Li, Chun Sing, Massé, Frédéric, McKay, Daniel J., Mellon, Christophe, Nicoll-Griffith, Deborah A., Oballa, Renata M., Percival, M. David, Riendeau, Denis, Robichaud, Joël, Rodan, Gideon A., Rodan, Sevgi B., Seto, Carmai, Thérien, Michel, Truong, Vouy Linh, Wesolowski, Gregg, Young, Robert N., Zamboni, Robert, Black, W. Cameron
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Get full text
Journal Article