Structural basis for alcohol modulation of a pentameric ligand-gated ion channel
Howard, Rebecca J, Murail, Samuel, Ondricek, Kathryn E, Corringer, Pierre-Jean, Lindahl, Erik, Trudell, James R, Harris, R. Adron
Published in Proceedings of the National Academy of Sciences - PNAS (19.07.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (19.07.2011)
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Journal Article
Residues in Transmembrane Segments of the P2X4 Receptor Contribute to Channel Function and Ethanol Sensitivity
Popova, Maya, Rodriguez, Larry, Trudell, James R, Nguyen, Sylvia, Bloomfield, Michael, Davies, Daryl L, Asatryan, Liana
Published in International journal of molecular sciences (02.04.2020)
Published in International journal of molecular sciences (02.04.2020)
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Journal Article
Stabilization of the GluCl Ligand-Gated Ion Channel in the Presence and Absence of Ivermectin
Yoluk, Özge, Brömstrup, Torben, Bertaccini, Edward J., Trudell, James R., Lindahl, Erik
Published in Biophysical journal (06.08.2013)
Published in Biophysical journal (06.08.2013)
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Journal Article
Coupling of agonist binding to channel gating in the GABAa receptor
KASH, Thomas L, JENKINS, Andrew, KELLEY, Jill C, TRUDELL, James R, HARRISON, Nell L
Published in Nature (London) (16.01.2003)
Published in Nature (London) (16.01.2003)
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Journal Article
P2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disorders
Franklin, Kelle M, Asatryan, Liana, Jakowec, Michael W, Trudell, James R, Bell, Richard L, Davies, Daryl L
Published in Frontiers in neuroscience (24.06.2014)
Published in Frontiers in neuroscience (24.06.2014)
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Journal Article
Anesthetics and ion channels: molecular models and sites of action
Yamakura, T, Bertaccini, E, Trudell, J R, Harris, R A
Published in Annual review of pharmacology and toxicology (01.01.2001)
Published in Annual review of pharmacology and toxicology (01.01.2001)
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Journal Article
Inhibition versus Potentiation of Ligand-Gated Ion Channels Can Be Altered by a Single Mutation that Moves Ligands between Intra- and Intersubunit Sites
Brömstrup, Torben, Howard, Rebecca J., Trudell, James R., Harris, R. Adron, Lindahl, Erik
Published in Structure (London) (06.08.2013)
Published in Structure (London) (06.08.2013)
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Journal Article
Molecular targets and mechanisms for ethanol action in glycine receptors
Perkins, Daya I, Trudell, James R, Crawford, Daniel K, Alkana, Ronald L, Davies, Daryl L
Published in Pharmacology & therapeutics (Oxford) (01.07.2010)
Published in Pharmacology & therapeutics (Oxford) (01.07.2010)
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Journal Article
Loop 2 Structure in Glycine and GABAA Receptors Plays a Key Role in Determining Ethanol Sensitivity
Perkins, Daya I., Trudell, James R., Crawford, Daniel K., Asatryan, Liana, Alkana, Ronald L., Davies, Daryl L.
Published in The Journal of biological chemistry (02.10.2009)
Published in The Journal of biological chemistry (02.10.2009)
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Journal Article
Evidence for a Common Binding Cavity for Three General Anesthetics within the GABAA Receptor
Jenkins, Andrew, Greenblatt, Eric P, Faulkner, Howard J, Bertaccini, Edward, Light, Adam, Lin, Audrey, Andreasen, Alyson, Viner, Anna, Trudell, James R, Harrison, Neil L
Published in The Journal of neuroscience (15.03.2001)
Published in The Journal of neuroscience (15.03.2001)
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Journal Article
Manipulations of extracellular Loop 2 in α1 GlyR ultra-sensitive ethanol receptors (USERs) enhance receptor sensitivity to isoflurane, ethanol, and lidocaine, but not propofol
Naito, A, Muchhala, K.H, Trang, J, Asatryan, L, Trudell, J.R, Homanics, G.E, Alkana, R.L, Davies, D.L
Published in Neuroscience (25.06.2015)
Published in Neuroscience (25.06.2015)
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Journal Article
Mutation of a zinc-binding residue in the glycine receptor α1 subunit changes ethanol sensitivity in vitro and alcohol consumption in vivo
McCracken, Lindsay M, Blednov, Yuri A, Trudell, James R, Benavidez, Jillian M, Betz, Heinrich, Harris, R Adron
Published in The Journal of pharmacology and experimental therapeutics (01.02.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2013)
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