Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls
Maruyama, Masahiro, Shimada, Hitoshi, Suhara, Tetsuya, Shinotoh, Hitoshi, Ji, Bin, Maeda, Jun, Zhang, Ming-Rong, Trojanowski, John Q., Lee, Virginia M.-Y., Ono, Maiko, Masamoto, Kazuto, Takano, Harumasa, Sahara, Naruhiko, Iwata, Nobuhisa, Okamura, Nobuyuki, Furumoto, Shozo, Kudo, Yukitsuka, Chang, Qing, Saido, Takaomi C., Takashima, Akihiko, Lewis, Jada, Jang, Ming-Kuei, Aoki, Ichio, Ito, Hiroshi, Higuchi, Makoto
Published in Neuron (Cambridge, Mass.) (18.09.2013)
Published in Neuron (Cambridge, Mass.) (18.09.2013)
Get full text
Journal Article
Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation
Saito, Takashi, Mihira, Naomi, Matsuba, Yukio, Sasaguri, Hiroki, Hashimoto, Shoko, Narasimhan, Sneha, Zhang, Bin, Murayama, Shigeo, Higuchi, Makoto, Lee, Virginia M.Y., Trojanowski, John Q., Saido, Takaomi C.
Published in The Journal of biological chemistry (23.08.2019)
Published in The Journal of biological chemistry (23.08.2019)
Get full text
Journal Article
Spreading of pathology in neurodegenerative diseases: a focus on human studies
Brettschneider, Johannes, Tredici, Kelly Del, Lee, Virginia M.-Y., Trojanowski, John Q.
Published in Nature reviews. Neuroscience (01.02.2015)
Published in Nature reviews. Neuroscience (01.02.2015)
Get full text
Journal Article
Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
Guo, Jing L., Covell, Dustin J., Daniels, Joshua P., Iba, Michiyo, Stieber, Anna, Zhang, Bin, Riddle, Dawn M., Kwong, Linda K., Xu, Yan, Trojanowski, John Q., Lee, Virginia M.Y.
Published in Cell (03.07.2013)
Published in Cell (03.07.2013)
Get full text
Journal Article
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
Jack, Clifford R, Prof Dr, Knopman, David S, Prof, Jagust, William J, Prof, Petersen, Ronald C, Prof, Weiner, Michael W, Prof, Aisen, Paul S, Prof, Shaw, Leslie M, Prof, Vemuri, Prashanthi, PhD, Wiste, Heather J, Weigand, Stephen D, Lesnick, Timothy G, Pankratz, Vernon S, PhD, Donohue, Michael C, PhD, Trojanowski, John Q, Prof
Published in Lancet neurology (01.02.2013)
Published in Lancet neurology (01.02.2013)
Get full text
Journal Article
Unique pathological tau conformers from Alzheimer's brains transmit tau pathology in nontransgenic mice
Guo, Jing L, Narasimhan, Sneha, Changolkar, Lakshmi, He, Zhuohao, Stieber, Anna, Zhang, Bin, Gathagan, Ronald J, Iba, Michiyo, McBride, Jennifer D, Trojanowski, John Q, Lee, Virginia M Y
Published in The Journal of experimental medicine (14.11.2016)
Published in The Journal of experimental medicine (14.11.2016)
Get full text
Journal Article
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative
Karikari, Thomas K., Benedet, Andréa L., Ashton, Nicholas J., Lantero Rodriguez, Juan, Snellman, Anniina, Suárez-Calvet, Marc, Saha-Chaudhuri, Paramita, Lussier, Firoza, Kvartsberg, Hlin, Rial, Alexis Moscoso, Pascoal, Tharick A., Andreasson, Ulf, Schöll, Michael, Weiner, Michael W., Rosa-Neto, Pedro, Trojanowski, John Q., Shaw, Leslie M., Blennow, Kaj, Zetterberg, Henrik
Published in Molecular psychiatry (01.02.2021)
Published in Molecular psychiatry (01.02.2021)
Get full text
Journal Article
Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy
Iba, Michiyo, Guo, Jing L, McBride, Jennifer D, Zhang, Bin, Trojanowski, John Q, Lee, Virginia M-Y
Published in The Journal of neuroscience (16.01.2013)
Published in The Journal of neuroscience (16.01.2013)
Get full text
Journal Article
Current state of Alzheimer’s fluid biomarkers
Molinuevo, José Luis, Ayton, Scott, Batrla, Richard, Bednar, Martin M., Bittner, Tobias, Cummings, Jeffrey, Fagan, Anne M., Hampel, Harald, Mielke, Michelle M., Mikulskis, Alvydas, O’Bryant, Sid, Scheltens, Philip, Sevigny, Jeffrey, Shaw, Leslie M., Soares, Holly D., Tong, Gary, Trojanowski, John Q., Zetterberg, Henrik, Blennow, Kaj
Published in Acta neuropathologica (01.12.2018)
Published in Acta neuropathologica (01.12.2018)
Get full text
Journal Article
Cerebrospinal fluid neurogranin: relation to cognition and neurodegeneration in Alzheimer's disease
Portelius, Erik, Zetterberg, Henrik, Skillbäck, Tobias, Törnqvist, Ulrika, Andreasson, Ulf, Trojanowski, John Q, Weiner, Michael W, Shaw, Leslie M, Mattsson, Niklas, Blennow, Kaj
Published in Brain (London, England : 1878) (01.11.2015)
Published in Brain (London, England : 1878) (01.11.2015)
Get full text
Journal Article
Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain
Narasimhan, Sneha, Guo, Jing L, Changolkar, Lakshmi, Stieber, Anna, McBride, Jennifer D, Silva, Luisa V, He, Zhuohao, Zhang, Bin, Gathagan, Ronald J, Trojanowski, John Q, Lee, Virginia M Y
Published in The Journal of neuroscience (22.11.2017)
Published in The Journal of neuroscience (22.11.2017)
Get full text
Journal Article
Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo
Porta, Sílvia, Xu, Yan, Restrepo, Clark R., Kwong, Linda K., Zhang, Bin, Brown, Hannah J., Lee, Edward B., Trojanowski, John Q., Lee, Virginia M.-Y.
Published in Nature communications (11.10.2018)
Published in Nature communications (11.10.2018)
Get full text
Journal Article
α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration
Tran, Hien T., Chung, Charlotte Hiu-Yan, Iba, Michiyo, Zhang, Bin, Trojanowski, John Q., Luk, Kelvin C., Lee, Virginia M.Y.
Published in Cell reports (Cambridge) (26.06.2014)
Published in Cell reports (Cambridge) (26.06.2014)
Get full text
Journal Article
Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders
Olsson, Bob, Portelius, Erik, Cullen, Nicholas C, Sandelius, Åsa, Zetterberg, Henrik, Andreasson, Ulf, Höglund, Kina, Irwin, David J, Grossman, Murray, Weintraub, Daniel, Chen-Plotkin, Alice, Wolk, David, McCluskey, Leo, Elman, Lauren, Shaw, Leslie M, Toledo, Jon B, McBride, Jennifer, Hernandez-Con, Pilar, Lee, Virginia M-Y, Trojanowski, John Q, Blennow, Kaj
Published in Archives of neurology (Chicago) (01.03.2019)
Published in Archives of neurology (Chicago) (01.03.2019)
Get full text
Journal Article
Brain Microvascular Pericytes in Vascular Cognitive Impairment and Dementia
Uemura, Maiko T, Maki, Takakuni, Ihara, Masafumi, Lee, Virginia M Y, Trojanowski, John Q
Published in Frontiers in aging neuroscience (14.04.2020)
Published in Frontiers in aging neuroscience (14.04.2020)
Get full text
Journal Article
Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease
Nativio, Raffaella, Donahue, Greg, Berson, Amit, Lan, Yemin, Amlie-Wolf, Alexandre, Tuzer, Ferit, Toledo, Jon B., Gosai, Sager J., Gregory, Brian D., Torres, Claudio, Trojanowski, John Q., Wang, Li-San, Johnson, F. Brad, Bonini, Nancy M., Berger, Shelley L.
Published in Nature neuroscience (01.04.2018)
Published in Nature neuroscience (01.04.2018)
Get full text
Journal Article
Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy
Spiller, Krista J., Restrepo, Clark R., Khan, Tahiyana, Dominique, Myrna A., Fang, Terry C., Canter, Rebecca G., Roberts, Christopher J., Miller, Kelly R., Ransohoff, Richard M., Trojanowski, John Q., Lee, Virginia M.-Y.
Published in Nature neuroscience (01.03.2018)
Published in Nature neuroscience (01.03.2018)
Get full text
Journal Article
Amyotrophic lateral sclerosis—a model of corticofugal axonal spread
Braak, Heiko, Brettschneider, Johannes, Ludolph, Albert C., Lee, Virginia M., Trojanowski, John Q., Tredici, Kelly Del
Published in Nature reviews. Neurology (01.12.2013)
Published in Nature reviews. Neurology (01.12.2013)
Get full text
Journal Article
Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies
Ono, Maiko, Sahara, Naruhiko, Kumata, Katsushi, Ji, Bin, Ni, Ruiqing, Koga, Shunsuke, Dickson, Dennis W, Trojanowski, John Q, Lee, Virginia M-Y, Yoshida, Mari, Hozumi, Isao, Yoshiyama, Yasumasa, van Swieten, John C, Nordberg, Agneta, Suhara, Tetsuya, Zhang, Ming-Rong, Higuchi, Makoto
Published in Brain (London, England : 1878) (01.03.2017)
Published in Brain (London, England : 1878) (01.03.2017)
Get full text
Journal Article