In memory of Norman Bowery (1944–2016)
Trist, David G, Kenakin, Terry P, Blackburn, Thomas P
Published in Current opinion in pharmacology (01.08.2017)
Published in Current opinion in pharmacology (01.08.2017)
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Journal Article
Efficacy of vestipitant, a neurokinin-1 receptor antagonist, in primary insomnia
Ratti, Emiliangelo, Carpenter, David J, Zamuner, Stefano, Fernandes, Sofia, Squassante, Lisa, Danker-Hopfe, Heidi, Archer, Graeme, Robertson, Jonathan, Alexander, Robert, Trist, David G, Merlo-Pich, Emilio
Published in Sleep (New York, N.Y.) (01.12.2013)
Published in Sleep (New York, N.Y.) (01.12.2013)
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Journal Article
Why receptor reserve matters for neurokinin1 (NK1) receptor antagonists
Trist, David G, Ratti, Emiliangelo, Bye, Alan
Published in Journal of receptors and signal transduction (01.12.2013)
Published in Journal of receptors and signal transduction (01.12.2013)
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Journal Article
Discovery Process and Pharmacological Characterization of 2-(S)-(4-Fluoro-2-methylphenyl)piperazine-1-carboxylic Acid [1-(R)-(3,5-Bis-trifluoromethylphenyl)ethyl]methylamide (Vestipitant) as a Potent, Selective, and Orally Active NK1 Receptor Antagonist
Di Fabio, Romano, Griffante, Cristiana, Alvaro, Giuseppe, Pentassuglia, Giorgio, Pizzi, Domenica A, Donati, Daniele, Rossi, Tino, Guercio, Giuseppe, Mattioli, Mario, Cimarosti, Zadeo, Marchioro, Carla, Provera, Stefano, Zonzini, Laura, Montanari, Dino, Melotto, Sergio, Gerrard, Philip A, Trist, David G, Ratti, Emiliangelo, Corsi, Mauro
Published in Journal of medicinal chemistry (28.05.2009)
Published in Journal of medicinal chemistry (28.05.2009)
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Journal Article
A selective neurokinin-1 receptor antagonist in chronic PTSD: A randomized, double-blind, placebo-controlled, proof-of-concept trial
Mathew, Sanjay J, Vythilingam, Meena, Murrough, James W, Zarate, Carlos A, Feder, Adriana, Luckenbaugh, David A, Kinkead, Becky, Parides, Michael K, Trist, David G, Bani, Massimo S, Bettica, Paolo U, Ratti, Emiliangelo M, Charney, Dennis S
Published in European neuropsychopharmacology (01.03.2011)
Published in European neuropsychopharmacology (01.03.2011)
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Journal Article
Discovery and Biological Characterization of (2R,4S)-1′-Acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methyl-4,4′-bipiperidine-1-carboxamide as a New Potent and Selective Neurokinin 1 (NK1) Receptor Antagonist Clinical Candidate
Di Fabio, Romano, Alvaro, Giuseppe, Griffante, Cristiana, Pizzi, Domenica A, Donati, Daniele, Mattioli, Mario, Cimarosti, Zadeo, Guercio, Giuseppe, Marchioro, Carla, Provera, Stefano, Zonzini, Laura, Montanari, Dino, Melotto, Sergio, Gerrard, Philip A, Trist, David G, Ratti, Emiliangelo, Corsi, Mauro
Published in Journal of medicinal chemistry (24.02.2011)
Published in Journal of medicinal chemistry (24.02.2011)
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Journal Article
Synthesis and structure–activity relationship of new 1,5-dialkyl-1,5-benzodiazepines as cholecystokinin-2 receptor antagonists
Roberts, Karen, Ursini, Antonella, Barnaby, Robert, Cassarà, Paolo G., Corsi, Mauro, Curotto, Giovanni, Donati, Daniele, Feriani, Aldo, Finizia, Gabriella, Marchioro, Carla, Niccolai, Daniela, Oliosi, Beatrice, Polinelli, Stefano, Ratti, Emiliangelo, Reggiani, Angelo, Tedesco, Giovanna, Tranquillini, Maria E., Trist, David G., van Amsterdam, Franciscus T.M.
Published in Bioorganic & medicinal chemistry (15.07.2011)
Published in Bioorganic & medicinal chemistry (15.07.2011)
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Journal Article
Synthesis and Pharmacological Characterization of Novel Druglike Corticotropin-Releasing Factor 1 Antagonists
Fabio, Romano Di, St-Denis, Yves, Sabbatini, Fabio M, Andreotti, Daniele, Arban, Roberto, Bernasconi, Giovanni, Braggio, Simone, Blaney, Frank E, Capelli, Anna M, Castiglioni, Emiliano, Modugno, Enza Di, Donati, Daniele, Fazzolari, Elettra, Ratti, Emiliangelo, Feriani, Aldo, Contini, Stefania, Gentile, Gabriella, Ghirlanda, Damiano, Provera, Stefano, Marchioro, Carla, Roberts, Karen L, Mingardi, Anna, Mattioli, Mario, Nalin, Arnaldo, Pavone, Francesca, Spada, Simone, Trist, David G, Worby, Angela
Published in Journal of medicinal chemistry (11.12.2008)
Published in Journal of medicinal chemistry (11.12.2008)
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Journal Article