Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1
Tripathi, Durga N., Chowdhury, Rajdeep, Trudel, Laura J., Tee, Andrew R., Slack, Rebecca S., Walker, Cheryl Lyn, Wogan, Gerald N.
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2013)
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Association of High-Intensity Exercise with Renal Medullary Carcinoma in Individuals with Sickle Cell Trait: Clinical Observations and Experimental Animal Studies
Shapiro, Daniel D, Soeung, Melinda, Perelli, Luigi, Dondossola, Eleonora, Surasi, Devaki Shilpa, Tripathi, Durga N, Bertocchio, Jean-Philippe, Carbone, Federica, Starbuck, Michael W, Van Alstine, Michael L, Rao, Priya, Katz, Matthew H G, Parker, Nathan H, Shah, Amishi Y, Carugo, Alessandro, Heffernan, Timothy P, Schadler, Keri L, Logothetis, Christopher, Walker, Cheryl L, Wood, Christopher G, Karam, Jose A, Draetta, Giulio F, Tannir, Nizar M, Genovese, Giannicola, Msaouel, Pavlos
Published in Cancers (30.11.2021)
Published in Cancers (30.11.2021)
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Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy
Shapiro, Daniel D., Zacharias, Niki Millward, Tripathi, Durga N., Karki, Menuka, Bertocchio, Jean‐Philippe, Soeung, Melinda, He, Rong, Westerman, Mary E., Gao, Jianjun, Rao, Priya, Lam, Truong N. A., Jonasch, Eric, Perelli, Luigi, Cheng, Emily H., Carugo, Alessandro, Heffernan, Timothy P., Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M., Karam, Jose A., Msaouel, Pavlos
Published in Clinical and translational medicine (01.05.2023)
Published in Clinical and translational medicine (01.05.2023)
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p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
Carugo, Alessandro, Minelli, Rosalba, Sapio, Luigi, Soeung, Melinda, Carbone, Federica, Robinson, Frederick S., Tepper, James, Chen, Ziheng, Lovisa, Sara, Svelto, Maria, Amin, Samirkumar, Srinivasan, Sanjana, Del Poggetto, Edoardo, Loponte, Sara, Puca, Francesca, Dey, Prasenjit, Malouf, Gabriel G., Su, Xiaoping, Li, Liren, Lopez-Terrada, Dolores, Rakheja, Dinesh, Lazar, Alexander J., Netto, George J., Rao, Priya, Sgambato, Alessandro, Maitra, Anirban, Tripathi, Durga N., Walker, Cheryl L., Karam, Jose A., Heffernan, Timothy P., Viale, Andrea, Roberts, Charles W.M., Msaouel, Pavlos, Tannir, Nizar M., Draetta, Giulio F., Genovese, Giannicola
Published in Cancer cell (11.02.2019)
Published in Cancer cell (11.02.2019)
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Journal Article
A cytoskeletal function for PBRM1 reading methylated microtubules
Karki, Menuka, Jangid, Rahul K, Anish, Ramakrishnan, Seervai, Riyad N H, Bertocchio, Jean-Philippe, Hotta, Takashi, Msaouel, Pavlos, Jung, Sung Yun, Grimm, Sandra L, Coarfa, Cristian, Weissman, Bernard E, Ohi, Ryoma, Verhey, Kristen J, Hodges, H Courtney, Burggren, Warren, Dere, Ruhee, Park, In Young, Prasad, B V Venkataram, Rathmell, W Kimryn, Walker, Cheryl L, Tripathi, Durga N
Published in Science advances (02.04.2021)
Published in Science advances (02.04.2021)
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Journal Article
Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
Msaouel, Pavlos, Malouf, Gabriel G., Su, Xiaoping, Yao, Hui, Tripathi, Durga N., Soeung, Melinda, Gao, Jianjun, Rao, Priya, Coarfa, Cristian, Creighton, Chad J., Bertocchio, Jean-Philippe, Kunnimalaiyaan, Selvi, Multani, Asha S., Blando, Jorge, He, Rong, Shapiro, Daniel D., Perelli, Luigi, Srinivasan, Sanjana, Carbone, Federica, Pilié, Patrick G., Karki, Menuka, Seervai, Riyad N.H., Vokshi, Bujamin H., Lopez-Terrada, Dolores, Cheng, Emily H., Tang, Ximing, Lu, Wei, Wistuba, Ignacio I., Thompson, Timothy C., Davidson, Irwin, Giuliani, Virginia, Schlacher, Katharina, Carugo, Alessandro, Heffernan, Timothy P., Sharma, Padmanee, Karam, Jose A., Wood, Christopher G., Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M.
Published in Cancer cell (11.05.2020)
Published in Cancer cell (11.05.2020)
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Journal Article
Abstract 1247: Targeting neddylation in combination with cytotoxic chemotherapy for the treatment of renal medullary carcinoma
Shapiro, Daniel D., Zacharias, Niki Millward, Tripathi, Durga N., Bertocchio, Jean-Philippe, Soeung, Melinda, Rao, Priya, Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M., Wood, Christopher G., Karam, Jose A., Msaouel, Pavlos
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Nutraceuticals against Neurodegeneration: A Mechanistic Insight
Dadhania, Vivekkumar P, Trivedi, Priyanka P, Vikram, Ajit, Tripathi, Durga Nand
Published in Current neuropharmacology (01.08.2016)
Published in Current neuropharmacology (01.08.2016)
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Abstract 4815: Differential expression profiling of long noncoding RNA establishes UCA1 as a hallmark of renal medullary carcinoma
Msaouel, Pavlos, Malouf, Gabriel G., Su, Xiaoping, Yao, Hui, Tripathi, Durga N., Gao, Jianjun, Rao, Priya, Bertocchio, Jean-Philippe, Karam, Jose, Wood, Christopher G., Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 2042: A cytoskeletal function for PBRM1: reading methylated microtubules to maintain genomic stability
Karki, Menuka, Jangid, Rahul, Anish, Ramakrishnan, Seervai, Riyad N., Bertocchio, Jean-Philippe, Hotta, Takashi, Msaouel, Pavlos, Jung, Sung Y., Grimm, Sandra L., Coarfa, Cristian, Weissman, Bernard E., Ohi, Ryoma, Verhey, Kristen J., Hodges, Courtney H., Dere, Ruhee, Park, In Young, Prasad, B. V. Venkataram, Rathmell, W. Kimryn, Walker, Cheryl L., Tripathi, Durga N.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma
Chiang, Yun-Chen, Park, In-Young, Terzo, Esteban A, Tripathi, Durga Nand, Mason, Frank M, Fahey, Catherine C, Karki, Menuka, Shuster, Charles B, Sohn, Bo-Hwa, Chowdhury, Pratim, Powell, Reid T, Ohi, Ryoma, Tsai, Yihsuan S, de Cubas, Aguirre A, Khan, Abid, Davis, Ian J, Strahl, Brian D, Parker, Joel S, Dere, Ruhee, Walker, Cheryl L, Rathmell, W Kimryn
Published in Cancer research (Chicago, Ill.) (15.06.2018)
Published in Cancer research (Chicago, Ill.) (15.06.2018)
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Journal Article
Comparative transcriptomic profiling of renal medullary carcinoma (RMC) to determine distinct signatures and pathways associated with response to chemotherapy
Msaouel, Pavlos, Malouf, Gabriel G., Su, Xiaoping, Yao, Hui, Tripathi, Durga N, Gao, Jianjun, Rao, Priya, He, Rong, Karam, Jose A., Wood, Christopher G., Walker, Cheryl Lyn, Tannir, Nizar M.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
Effect of SMARCB1 deficiency in renal medullary carcinoma (RMC) on genes associated with nucleosome assembly and telomere organization
Msaouel, Pavlos, Malouf, Gabriel G., Su, Xiaoping, Yao, Hui, Tripathi, Durga N, Gao, Jianjun, Rao, Priya, He, Rong, Karam, Jose A., Wood, Christopher G., Walker, Cheryl Lyn, Tannir, Nizar M.
Published in Journal of clinical oncology (20.02.2018)
Published in Journal of clinical oncology (20.02.2018)
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Journal Article
Abstract 2702: Hyperprogression due to myeloid mimicry in renal medullary carcinoma treated with nivolumab plus ipilimumab
Soeung, Melinda, Yan, Xinmiao, Zhang, Li, Perelli, Luigi, Chen, Jianfeng, Tidwell, Becky Slack, Khan, Hania, Le, Courtney N., Lam, Truong N., Bhattacharya, Nirjar, Shah, Rutvi, Ho, I-Lin, Chen, Ziheng, Lundgren, Sebastian R., Feng, Ningping, Zanca, Ciro, Karki, Menuka, Millward, Niki Marie Zacharias, He, Rong, Sheth, Rahul A., Tharakeswara, Bathala K., Rao, Priya, Daw, Najat C., Tripathi, Durga N., Walker, Cheryl L., Han, Guangchun, Chu, Yanshuo, Wang, Ruiping, Dang, Minghao, Dai, Enyu, Peng, Fuduan, Liu, Yunhe, Jadhav, Akshaya S., Lang, Wenhua, Arrechedera, Claudio A., Clemente, Leticia Campos, Parra-Cuentas, Edwin R., Lu, Hsinyi, Haymaker, Cara, Wistuba, Ignacio I., Futreal, Andrew, Heffernan, Timothy, Viale, Andrea, Draetta, Giulio F., Tannir, Nizar M., Gao, Jianjun, Wang, Linghua, Genovese, Giannicola, Msaouel, Pavlos
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract 312: Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis
Liu, Xian-De, Yao, Jun, Tripathi, Durga N., Ding, Zhiyong, Xu, Yi, Sun, Mianen, Zhang, Jiangwei, Bai, Shanshan, German, Peter, Hoang, Anh, Zhou, Lijun, Zhang, Xuesong, Conti, Claudio J., Efstathiou, Eleni, Eissa, Tony N., Mills, Gordon B., Walker, Cheryl L., Jonasch, Eric
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
A Cytoskeletal Function for PBRM1 Reading Methylated Microtubules
Karki, Menuka, Jangid, Rahul K, Seervai, Riyad Nh, Jean-Philippe Bertocchio, Hotta, Takashi, Msaouel, Pavlos, Jung, Sung Y, Grimm, Sandra L, Coarfa, Cristian, Weissman, Bernard E, Ohi, Ryoma, Verhey, Kristen J, Hodges, Courtney H, Dere, Ruhee, Park, In-Young, Rathmell, Kimryn W, Walker, Cheryl L, Tripathi, Durga N
Published in bioRxiv (22.04.2020)
Published in bioRxiv (22.04.2020)
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