Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine
Trinh, Michael N., Brown, Michael S., Goldstein, Joseph L., Han, Jaeil, Vale, Gonçalo, McDonald, Jeffrey G., Seemann, Joachim, Mendell, Joshua T., Lu, Feiran
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.2020)
Get full text
Journal Article
Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol
Trinh, Michael N, Brown, Michael S, Seemann, Joachim, Vale, Gonçalo, McDonald, Jeffrey G, Goldstein, Joseph L, Lu, Feiran
Published in Proceedings of the National Academy of Sciences - PNAS (11.01.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (11.01.2022)
Get full text
Journal Article
Triazoles inhibit cholesterol export from lysosomes by binding to NPC1
Trinh, Michael N., Lu, Feiran, Li, Xiaochun, Das, Akash, Liang, Qiren, De Brabander, Jef K., Brown, Michael S., Goldstein, Joseph L.
Published in Proceedings of the National Academy of Sciences - PNAS (03.01.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (03.01.2017)
Get full text
Journal Article
3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport
Li, Xiaochun, Lu, Feiran, Trinh, Michael N., Schmiege, Philip, Seemann, Joachim, Wang, Jiawei, Blobel, Günter
Published in Proceedings of the National Academy of Sciences - PNAS (22.08.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (22.08.2017)
Get full text
Journal Article
Exome wide association study for blood lipids in 1,158,017 individuals from diverse populations
Koyama, Satoshi, Yu, Zhi, Choi, Seung Hoan, Jurgens, Sean J, Selvaraj, Margaret Sunitha, Klarin, Derek, Huffman, Jennifer E, Clarke, Shoa L, Trinh, Michael N, Ravi, Akshaya, Dron, Jacqueline S, Spinks, Catherine, Surakka, Ida, Bhatnagar, Aarushi, Lannery, Kim, Hornsby, Whitney, Damrauer, Scott M, Chang, Kyong-Mi, Lynch, Julie A, Assimes, Themistocles L, Tsao, Philip S, Rader, Daniel J, Cho, Kelly, Peloso, Gina M, Ellinor, Patrick T, Sun, Yan V, Wilson, Peter Wf, Program, Million Veteran, Natarajan, Pradeep
Published in medRxiv : the preprint server for health sciences (18.09.2024)
Get more information
Published in medRxiv : the preprint server for health sciences (18.09.2024)
Journal Article