High-throughput matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry–based deubiquitylating enzyme assay for drug discovery
De Cesare, Virginia, Moran, Jennifer, Traynor, Ryan, Knebel, Axel, Ritorto, Maria Stella, Trost, Matthias, McLauchlan, Hilary, Hastie, C. James, Davies, Paul
Published in Nature protocols (01.12.2020)
Published in Nature protocols (01.12.2020)
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Generation of a chemical genetic model for JAK3
Remenyi, Judit, Naik, Rangeetha Jayaprakash, Wang, Jinhua, Razsolkov, Momchil, Verano, Alyssa, Cai, Quan, Tan, Li, Toth, Rachel, Raggett, Samantha, Baillie, Carla, Traynor, Ryan, Hastie, C. James, Gray, Nathanael S., Arthur, J. Simon C.
Published in Scientific reports (12.05.2021)
Published in Scientific reports (12.05.2021)
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Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases
Banerjee, Sourav, Buhrlage, Sara J, Huang, Hai-Tsang, Deng, Xianming, Zhou, Wenjun, Wang, Jinhua, Traynor, Ryan, Prescott, Alan R, Alessi, Dario R, Gray, Nathanael S
Published in Biochemical journal (01.01.2014)
Published in Biochemical journal (01.01.2014)
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Journal Article
Kinome-wide Selectivity Profiling of ATP-competitive Mammalian Target of Rapamycin (mTOR) Inhibitors and Characterization of Their Binding Kinetics
Liu, Qingsong, Kirubakaran, Sivapriya, Hur, Wooyoung, Niepel, Mario, Westover, Kenneth, Thoreen, Carson C., Wang, Jinhua, Ni, Jing, Patricelli, Matthew P., Vogel, Kurt, Riddle, Steve, Waller, David L., Traynor, Ryan, Sanda, Takaomi, Zhao, Zheng, Kang, Seong A., Zhao, Jean, Look, A. Thomas, Sorger, Peter K., Sabatini, David M., Gray, Nathanael S.
Published in The Journal of biological chemistry (23.03.2012)
Published in The Journal of biological chemistry (23.03.2012)
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Journal Article
Design and high-throughput implementation of MALDI-TOF/MS-based assays for Parkin E3 ligase activity
Traynor, Ryan, Moran, Jennifer, Stevens, Michael, Antico, Odetta, Knebel, Axel, Behrouz, Bahareh, Merchant, Kalpana, Hastie, C. James, Davies, Paul, Muqit, Miratul M.K., De Cesare, Virginia
Published in Cell reports methods (26.02.2024)
Published in Cell reports methods (26.02.2024)
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Journal Article
Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A
Sarno, Stefania, Mazzorana, Marco, Traynor, Ryan, Ruzzene, Maria, Cozza, Giorgio, Pagano, Mario A., Meggio, Flavio, Zagotto, Giuseppe, Battistutta, Roberto, Pinna, Lorenzo A.
Published in Cellular and molecular life sciences : CMLS (01.02.2012)
Published in Cellular and molecular life sciences : CMLS (01.02.2012)
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Journal Article
Smart Cement Composites for Durable and Intelligent Infrastructure
Suryanto, Benny, McCarter, W. John, Starrs, Gerry, Wilson, Sam A., Traynor, Ryan M.
Published in Procedia engineering (2015)
Published in Procedia engineering (2015)
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Journal Article
Comparison of the specificity of Trk inhibitors in recombinant and neuronal assays
Martin, Kirsty J., Shpiro, Natalia, Traynor, Ryan, Elliott, Matthew, Arthur, J. Simon C.
Published in Neuropharmacology (01.07.2011)
Published in Neuropharmacology (01.07.2011)
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Journal Article
Elaboration of a MALDI-TOF Mass Spectrometry-based Assay of Parkin Activity and High-Throughput screening platform for Parkin Activators
Traynor, Ryan, Moran, Jennifer, Stevens, Michael U, Knebel, Axel, Bahareh Behrouz, Merchant, Kalpana, Hastie, C James, Davies, Paul, Muqit, Miratul, De Cesare, Virginia
Published in bioRxiv (04.03.2022)
Published in bioRxiv (04.03.2022)
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