The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel NaV1.8 to Enhance Activation
Deuis, Jennifer R., Ragnarsson, Lotten, Robinson, Samuel D., Dekan, Zoltan, Chan, Lerena, Jin, Ai-Hua, Tran, Poanna, McMahon, Kirsten L., Li, Shengnan, Wood, John N., Cox, James J., King, Glenn F., Herzig, Volker, Vetter, Irina
Published in Frontiers in pharmacology (14.01.2022)
Published in Frontiers in pharmacology (14.01.2022)
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Journal Article
GRIN1 variants associated with neurodevelopmental disorders reveal channel gating pathomechanisms
Ragnarsson, Lotten, Zhang, Zihan, Das, Sooraj S., Tran, Poanna, Andersson, Åsa, Portes, Vincent, Desmettre Altuzarra, Cecilia, Remerand, Ganaelle, Labalme, Audrey, Chatron, Nicolas, Sanlaville, Damien, Lesca, Gaetan, Anggono, Victor, Vetter, Irina, Keramidas, Angelo
Published in Epilepsia (Copenhagen) (01.12.2023)
Published in Epilepsia (Copenhagen) (01.12.2023)
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Journal Article
Changes in Potency and Subtype Selectivity of Bivalent NaV Toxins are Knot-Specific
Tran, Poanna, Tran, Hue N. T., McMahon, Kirsten L., Deuis, Jennifer R., Ragnarsson, Lotten, Norman, Alexander, Sharpe, Simon J., Payne, Richard J., Vetter, Irina, Schroeder, Christina I.
Published in Bioconjugate chemistry (21.06.2023)
Published in Bioconjugate chemistry (21.06.2023)
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Journal Article
Changes in Potency and Subtype Selectivity of Bivalent Na V Toxins are Knot-Specific
Tran, Poanna, Tran, Hue N T, McMahon, Kirsten L, Deuis, Jennifer R, Ragnarsson, Lotten, Norman, Alexander, Sharpe, Simon J, Payne, Richard J, Vetter, Irina, Schroeder, Christina I
Published in Bioconjugate chemistry (21.06.2023)
Published in Bioconjugate chemistry (21.06.2023)
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Journal Article
Enzymatic Ligation of a Pore Blocker Toxin and a Gating Modifier Toxin: Creating Double-Knotted Peptides with Improved Sodium Channel NaV1.7 Inhibition
Tran, Hue N. T, Tran, Poanna, Deuis, Jennifer R, Agwa, Akello J, Zhang, Alan H, Vetter, Irina, Schroeder, Christina I
Published in Bioconjugate chemistry (15.01.2020)
Published in Bioconjugate chemistry (15.01.2020)
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Journal Article
Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7
Agwa, Akello J., Tran, Poanna, Mueller, Alexander, Tran, Hue N.T., Deuis, Jennifer R., Israel, Mathilde R., McMahon, Kirsten L., Craik, David J., Vetter, Irina, Schroeder, Christina I.
Published in The Journal of biological chemistry (10.04.2020)
Published in The Journal of biological chemistry (10.04.2020)
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Journal Article
Evaluation of Efficient Non-reducing Enzymatic and Chemical Ligation Strategies for Complex Disulfide-Rich Peptides
Tran, Hue N. T, Tran, Poanna, Deuis, Jennifer R, McMahon, Kirsten L, Yap, Kuok, Craik, David J, Vetter, Irina, Schroeder, Christina I
Published in Bioconjugate chemistry (17.11.2021)
Published in Bioconjugate chemistry (17.11.2021)
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Journal Article
Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function
Jami, Sina, Deuis, Jennifer R., Klasfauseweh, Tabea, Cheng, Xiaoyang, Kurdyukov, Sergey, Chung, Felicity, Okorokov, Andrei L., Li, Shengnan, Zhang, Jiangtao, Cristofori-Armstrong, Ben, Israel, Mathilde R., Ju, Robert J., Robinson, Samuel D., Zhao, Peng, Ragnarsson, Lotten, Andersson, Åsa, Tran, Poanna, Schendel, Vanessa, McMahon, Kirsten L., Tran, Hue N. T., Chin, Yanni K.-Y., Zhu, Yifei, Liu, Junyu, Crawford, Theo, Purushothamvasan, Saipriyaa, Habib, Abdella M., Andersson, David A., Rash, Lachlan D., Wood, John N., Zhao, Jing, Stehbens, Samantha J., Mobli, Mehdi, Leffler, Andreas, Jiang, Daohua, Cox, James J., Waxman, Stephen G., Dib-Hajj, Sulayman D., Neely, G. Gregory, Durek, Thomas, Vetter, Irina
Published in Nature communications (28.04.2023)
Published in Nature communications (28.04.2023)
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Journal Article
Enzymatic Ligation of a Pore Blocker Toxin and a Gating Modifier Toxin: Creating Double-Knotted Peptides with Improved Sodium Channel Na V 1.7 Inhibition
Tran, Hue N T, Tran, Poanna, Deuis, Jennifer R, Agwa, Akello J, Zhang, Alan H, Vetter, Irina, Schroeder, Christina I
Published in Bioconjugate chemistry (15.01.2020)
Published in Bioconjugate chemistry (15.01.2020)
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Journal Article
Structural Conformation and Activity of Spider-Derived Inhibitory Cystine Knot Peptide Pn3a Are Modulated by pH
Tran, Poanna, Crawford, Theo, Ragnarsson, Lotten, Deuis, Jennifer R., Mobli, Mehdi, Sharpe, Simon J., Schroeder, Christina I., Vetter, Irina
Published in ACS omega (25.07.2023)
Published in ACS omega (25.07.2023)
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Journal Article
The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel Na V 1.8 to Enhance Activation
Deuis, Jennifer R, Ragnarsson, Lotten, Robinson, Samuel D, Dekan, Zoltan, Chan, Lerena, Jin, Ai-Hua, Tran, Poanna, McMahon, Kirsten L, Li, Shengnan, Wood, John N, Cox, James J, King, Glenn F, Herzig, Volker, Vetter, Irina
Published in Frontiers in pharmacology (2021)
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Published in Frontiers in pharmacology (2021)
Journal Article
Pain-causing stinging nettle toxins target TMEM233 to modulate Na V 1.7 function
Jami, Sina, Deuis, Jennifer R, Klasfauseweh, Tabea, Cheng, Xiaoyang, Kurdyukov, Sergey, Chung, Felicity, Okorokov, Andrei L, Li, Shengnan, Zhang, Jiangtao, Cristofori-Armstrong, Ben, Israel, Mathilde R, Ju, Robert J, Robinson, Samuel D, Zhao, Peng, Ragnarsson, Lotten, Andersson, Åsa, Tran, Poanna, Schendel, Vanessa, McMahon, Kirsten L, Tran, Hue N T, Chin, Yanni K-Y, Zhu, Yifei, Liu, Junyu, Crawford, Theo, Purushothamvasan, Saipriyaa, Habib, Abdella M, Andersson, David A, Rash, Lachlan D, Wood, John N, Zhao, Jing, Stehbens, Samantha J, Mobli, Mehdi, Leffler, Andreas, Jiang, Daohua, Cox, James J, Waxman, Stephen G, Dib-Hajj, Sulayman D, Neely, G Gregory, Durek, Thomas, Vetter, Irina
Published in Nature communications (28.04.2023)
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Published in Nature communications (28.04.2023)
Journal Article