Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations
Han, Qifeng, Jones, Julia A., Nicely, Nathan I., Reed, Rachel K., Shen, Xiaoying, Mansouri, Katayoun, Louder, Mark, Trama, Ashley M., Alam, S. Munir, Edwards, Robert J., Bonsignori, Mattia, Tomaras, Georgia D., Korber, Bette, Montefiori, David C., Mascola, John R., Seaman, Michael S., Haynes, Barton F., Saunders, Kevin O.
Published in Nature communications (01.07.2019)
Published in Nature communications (01.07.2019)
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HIV-1 Envelope gp41 Antibodies Can Originate from Terminal Ileum B Cells that Share Cross-Reactivity with Commensal Bacteria
Trama, Ashley M., Moody, M. Anthony, Alam, S. Munir, Jaeger, Frederick H., Lockwood, Bradley, Parks, Robert, Lloyd, Krissey E., Stolarchuk, Christina, Scearce, Richard, Foulger, Andrew, Marshall, Dawn J., Whitesides, John F., Jeffries, Thomas L., Wiehe, Kevin, Morris, Lynn, Lambson, Bronwen, Soderberg, Kelly, Hwang, Kwan-Ki, Tomaras, Georgia D., Vandergrift, Nathan, Jackson, Katherine J.L., Roskin, Krishna M., Boyd, Scott D., Kepler, Thomas B., Liao, Hua-Xin, Haynes, Barton F.
Published in Cell host & microbe (13.08.2014)
Published in Cell host & microbe (13.08.2014)
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Cooperation between somatic mutation and germline-encoded residues enables antibody recognition of HIV-1 envelope glycans
Wu, Nelson R, Nicely, Nathan I, Lee, Esther M, Reed, Rachel K, Watts, Brian E, Cai, Fangping, Walkowicz, William E, Aussedat, Baptiste, Jones, Julia A, Eaton, Amanda, Trama, Ashley M, Alam, S Munir, Montefiori, David C, Haynes, Barton F, Saunders, Kevin O
Published in PLoS pathogens (01.12.2019)
Published in PLoS pathogens (01.12.2019)
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IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria
Hwang, Kwan-Ki, Trama, Ashley M, Kozink, Daniel M, Chen, Xi, Wiehe, Kevin, Cooper, Abby J, Xia, Shi-Mao, Wang, Minyue, Marshall, Dawn J, Whitesides, John, Alam, Munir, Tomaras, Georgia D, Allen, Steven L, Rai, Kanti R, McKeating, Jane, Catera, Rosa, Yan, Xiao-Jie, Chu, Charles C, Kelsoe, Garnett, Liao, Hua-Xin, Chiorazzi, Nicholas, Haynes, Barton F
Published in PloS one (10.03.2014)
Published in PloS one (10.03.2014)
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Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus
Zhang, Ruijun, Martinez, David R., Nguyen, Quang N., Pollara, Justin, Arifin, Trina, Stolarchuk, Christina, Foulger, Andrew, Amos, Josh D., Parks, Robert, Himes, Jonathon E., Wang, Minyue, Edwards, Regina W., Trama, Ashley M., Vandergrift, Nathan, Colvin, Lisa, Dewar, Ken, Juretic, Nikoleta, Wasserscheid, Jessica, Ferrari, Guido, Liao, Hua-Xin, Permar, Sallie R.
Published in Nature communications (06.07.2016)
Published in Nature communications (06.07.2016)
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Lymphocyte phenotypes in wild-caught rats suggest potential mechanisms underlying increased immune sensitivity in post-industrial environments
Trama, Ashley M, Holzknecht, Zoie E, Thomas, Anitra D, Su, Kuei-Ying, Lee, Sean M, Foltz, Emily E, Perkins, Sarah E, Lin, Shu S, Parker, William
Published in Cellular & molecular immunology (01.03.2012)
Published in Cellular & molecular immunology (01.03.2012)
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Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models
Saunders, Kevin O., Verkoczy, Laurent K., Jiang, Chuancang, Zhang, Jinsong, Parks, Robert, Chen, Haiyan, Housman, Max, Bouton-Verville, Hilary, Shen, Xiaoying, Trama, Ashley M., Scearce, Richard, Sutherland, Laura, Santra, Sampa, Newman, Amanda, Eaton, Amanda, Xu, Kai, Georgiev, Ivelin S., Joyce, M. Gordon, Tomaras, Georgia D., Bonsignori, Mattia, Reed, Steven G., Salazar, Andres, Mascola, John R., Moody, M. Anthony, Cain, Derek W., Centlivre, Mireille, Zurawski, Sandra, Zurawski, Gerard, Erickson, Harold P., Kwong, Peter D., Alam, S. Munir, Levy, Yves, Montefiori, David C., Haynes, Barton F.
Published in Cell reports (Cambridge) (26.12.2017)
Published in Cell reports (Cambridge) (26.12.2017)
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Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages
Zhang, Ruijun, Verkoczy, Laurent, Wiehe, Kevin, Munir Alam, S, Nicely, Nathan I, Santra, Sampa, Bradley, Todd, Pemble, 4th, Charles W, Zhang, Jinsong, Gao, Feng, Montefiori, David C, Bouton-Verville, Hilary, Kelsoe, Garnett, Larimore, Kevin, Greenberg, Phillip D, Parks, Robert, Foulger, Andrew, Peel, Jessica N, Luo, Kan, Lu, Xiaozhi, Trama, Ashley M, Vandergrift, Nathan, Tomaras, Georgia D, Kepler, Thomas B, Moody, M Anthony, Liao, Hua-Xin, Haynes, Barton F
Published in Science translational medicine (27.04.2016)
Published in Science translational medicine (27.04.2016)
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HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces gp41 Antibody Immunodominance in Rhesus Macaques
Han, Qifeng, Williams, Wilton B, Saunders, Kevin O, Seaton, Kelly E, Wiehe, Kevin J, Vandergrift, Nathan, Von Holle, Tarra A, Trama, Ashley M, Parks, Robert J, Luo, Kan, Gurley, Thaddeus C, Kepler, Thomas B, Marshall, Dawn J, Montefiori, David C, Sutherland, Laura L, Alam, Munir S, Whitesides, John F, Bowman, Cindy M, Permar, Sallie R, Graham, Barney S, Mascola, John R, Seed, Patrick C, Van Rompay, Koen K A, Tomaras, Georgia D, Moody, M Anthony, Haynes, Barton F
Published in Journal of virology (01.11.2017)
Published in Journal of virology (01.11.2017)
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A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
Kisalu, Neville K, Idris, Azza H, Weidle, Connor, Flores-Garcia, Yevel, Flynn, Barbara J, Sack, Brandon K, Murphy, Sean, Schön, Arne, Freire, Ernesto, Francica, Joseph R, Miller, Alex B, Gregory, Jason, March, Sandra, Liao, Hua-Xin, Haynes, Barton F, Wiehe, Kevin, Trama, Ashley M, Saunders, Kevin O, Gladden, Morgan A, Monroe, Anthony, Bonsignori, Mattia, Kanekiyo, Masaru, Wheatley, Adam K, McDermott, Adrian B, Farney, S Katie, Chuang, Gwo-Yu, Zhang, Baoshan, Kc, Natasha, Chakravarty, Sumana, Kwong, Peter D, Sinnis, Photini, Bhatia, Sangeeta N, Kappe, Stefan H I, Sim, B Kim Lee, Hoffman, Stephen L, Zavala, Fidel, Pancera, Marie, Seder, Robert A
Published in Nature medicine (01.04.2018)
Published in Nature medicine (01.04.2018)
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Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
Kisalu, Neville K, Idris, Azza H, Weidle, Connor, Flores-Garcia, Yevel, Flynn, Barbara J, Sack, Brandon K, Murphy, Sean, Schön, Arne, Freire, Ernesto, Francica, Joseph R, Miller, Alex B, Gregory, Jason, March, Sandra, Liao, Hua-Xin, Haynes, Barton F, Wiehe, Kevin, Trama, Ashley M, Saunders, Kevin O, Gladden, Morgan A, Monroe, Anthony, Bonsignori, Mattia, Kanekiyo, Masaru, Wheatley, Adam K, McDermott, Adrian B, Farney, S Katie, Chuang, Gwo-Yu, Zhang, Baoshan, Kc, Natasha, Chakravarty, Sumana, Kwong, Peter D, Sinnis, Photini, Bhatia, Sangeeta N, Kappe, Stefan H I, Sim, B Kim Lee, Hoffman, Stephen L, Zavala, Fidel, Pancera, Marie, Seder, Robert A
Published in Nature medicine (2019)
Published in Nature medicine (2019)
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A human monoclonal antibody prevents malaria infection and defines a new site of vulnerability on Plasmodium falciparum circumsporozoite protein
Kisalu, Neville K., Idris, Azza H., Weidle, Connor, Flores-Garcia, Yevel, Flynn, Barbara J., Sack, Brandon K., Murphy, Sean, Schön, Arne, Freire, Ernesto, Francica, Joseph R., Miller, Alex B., Gregory, Jason, March, Sandra, Liao, Hua-Xin, Haynes, Barton F., Wiehe, Kevin, Trama, Ashley M., Saunders, Kevin O., Gladden, Morgan A., Monroe, Anthony, Bonsignori, Mattia, Kanekiyo, Masaru, Wheatley, Adam K., McDermott, Adrian B., Farney, S. Katie, Chuang, Gwo-Yu, Zhang, Baoshan, Natasha, K C, Chakravarty, Sumana, Kwong, Peter D., Sinnis, Photini, Bhatia, Sangeeta N., Kappe, Stefan H. I., Sim, B. Kim Lee, Hoffman, Stephen L., Zavala, Fidel, Pancera, Marie, Seder, Robert A.
Published in Nature medicine (19.03.2018)
Published in Nature medicine (19.03.2018)
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The function and affinity maturation of HIV-1 gp120-specific monoclonal antibodies derived from colostral B cells
Jeffries, T L, Sacha, C R, Pollara, J, Himes, J, Jaeger, F H, Dennison, S M, McGuire, E, Kunz, E, Eudailey, J A, Trama, A M, LaBranche, C, Fouda, G G, Wiehe, K, Montefiori, D C, Haynes, B F, Liao, H-X, Ferrari, G, Alam, S M, Moody, M A, Permar, S R
Published in Mucosal immunology (01.03.2016)
Published in Mucosal immunology (01.03.2016)
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IGHV1-69 B Cell Chronic Lymphocytic Leukemia Antibodies Cross-React with HIV-1 and Hepatitis C Virus Antigens as Well as Intestinal Commensal Bacteria: e90725
Hwang, Kwan-Ki, Trama, Ashley M, Kozink, Daniel M, Chen, Xi, Wiehe, Kevin, Cooper, Abby J, Xia, Shi-Mao, Wang, Minyue, Marshall, Dawn J, Whitesides, John
Published in PloS one (01.03.2014)
Published in PloS one (01.03.2014)
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HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies
Williams, Wilton B, Liao, Hua-Xin, Moody, M Anthony, Kepler, Thomas B, Alam, S Munir, Gao, Feng, Wiehe, Kevin, Trama, Ashley M, Jones, Kathryn, Zhang, Ruijun, Song, Hongshuo, Marshall, Dawn J, Whitesides, John F, Sawatzki, Kaitlin, Hua, Axin, Liu, Pinghuang, Tay, Matthew Z, Seaton, Kelly E, Shen, Xiaoying, Foulger, Andrew, Lloyd, Krissey E, Parks, Robert, Pollara, Justin, Ferrari, Guido, Yu, Jae-Sung, Vandergrift, Nathan, Montefiori, David C, Sobieszczyk, Magdalena E, Hammer, Scott, Karuna, Shelly, Gilbert, Peter, Grove, Doug, Grunenberg, Nicole, McElrath, M Juliana, Mascola, John R, Koup, Richard A, Corey, Lawrence, Nabel, Gary J, Morgan, Cecilia, Churchyard, Gavin, Maenza, Janine, Keefer, Michael, Graham, Barney S, Baden, Lindsey R, Tomaras, Georgia D, Haynes, Barton F
Published in Science (American Association for the Advancement of Science) (14.08.2015)
Published in Science (American Association for the Advancement of Science) (14.08.2015)
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