Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling
Apriamashvili, Georgi, Vredevoogd, David W., Krijgsman, Oscar, Bleijerveld, Onno B., Ligtenberg, Maarten A., de Bruijn, Beaunelle, Boshuizen, Julia, Traets, Joleen J. H., D’Empaire Altimari, Daniela, van Vliet, Alex, Lin, Chun-Pu, Visser, Nils L., Londino, James D., Sanchez-Hodge, Rebekah, Oswalt, Leah E., Altinok, Selin, Schisler, Jonathan C., Altelaar, Maarten, Peeper, Daniel S.
Published in Nature communications (08.04.2022)
Published in Nature communications (08.04.2022)
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High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer
van den Broek, Evert, Dijkstra, Maurits J J, Krijgsman, Oscar, Sie, Daoud, Haan, Josien C, Traets, Joleen J H, van de Wiel, Mark A, Nagtegaal, Iris D, Punt, Cornelis J A, Carvalho, Beatriz, Ylstra, Bauke, Abeln, Sanne, Meijer, Gerrit A, Fijneman, Remond J A
Published in PloS one (16.09.2015)
Published in PloS one (16.09.2015)
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Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial
Nederlof, Iris, Isaeva, Olga I., de Graaf, Manon, Gielen, Robbert C. A. M., Bakker, Noor A. M., Rolfes, Adrianne L., Garner, Hannah, Boeckx, Bram, Traets, Joleen J. H., Mandjes, Ingrid A. M., de Maaker, Michiel, van Brussel, Thomas, Chelushkin, Maksim, Champanhet, Elisa, Lopez-Yurda, Marta, van de Vijver, Koen, van den Berg, José G., Hofland, Ingrid, Klioueva, Natasja, Mann, Ritse M., Loo, Claudette E., van Duijnhoven, Frederieke H., Skinner, Victoria, Luykx, Sylvia, Kerver, Emile, Kalashnikova, Ekaterina, van Dongen, Marloes G. J., Sonke, Gabe S., Linn, Sabine C., Blank, Christian U., de Visser, Karin E., Salgado, Roberto, Wessels, Lodewyk F. A., Drukker, Caroline A., Schumacher, Ton N., Horlings, Hugo M., Lambrechts, Diether, Kok, Marleen
Published in Nature medicine (01.11.2024)
Published in Nature medicine (01.11.2024)
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Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma
Vos, Joris L., Elbers, Joris B. W., Krijgsman, Oscar, Traets, Joleen J. H., Qiao, Xiaohang, van der Leun, Anne M., Lubeck, Yoni, Seignette, Iris M., Smit, Laura A., Willems, Stefan M., van den Brekel, Michiel W. M., Dirven, Richard, Baris Karakullukcu, M., Karssemakers, Luc, Klop, W. Martin C., Lohuis, Peter J. F. M., Schreuder, Willem H., Smeele, Ludi E., van der Velden, Lilly-Ann, Bing Tan, I., Onderwater, Suzanne, Jasperse, Bas, Vogel, Wouter V., Al-Mamgani, Abrahim, Keijser, Astrid, van der Noort, Vincent, Broeks, Annegien, Hooijberg, Erik, Peeper, Daniel S., Schumacher, Ton N., Blank, Christian U., de Boer, Jan Paul, Haanen, John B. A. G., Zuur, Charlotte L.
Published in Nature communications (22.12.2021)
Published in Nature communications (22.12.2021)
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TSC2 regulates tumor susceptibility to TRAIL‐mediated T‐cell killing by orchestrating mTOR signaling
Lin, Chun‐Pu, Traets, Joleen J H, Vredevoogd, David W, Visser, Nils L, Peeper, Daniel S
Published in The EMBO journal (01.03.2023)
Published in The EMBO journal (01.03.2023)
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A pan-cancer analysis of the microbiome in metastatic cancer
Battaglia, Thomas W., Mimpen, Iris L., Traets, Joleen J.H., van Hoeck, Arne, Zeverijn, Laurien J., Geurts, Birgit S., de Wit, Gijs F., Noë, Michaël, Hofland, Ingrid, Vos, Joris L., Cornelissen, Sten, Alkemade, Maartje, Broeks, Annegien, Zuur, Charlotte L., Cuppen, Edwin, Wessels, Lodewyk, van de Haar, Joris, Voest, Emile
Published in Cell (25.04.2024)
Published in Cell (25.04.2024)
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The Elongin BC Complex Negatively Regulates AXL and Marks a Differentiated Phenotype in Melanoma
Schieven, Sebastiaan M, Traets, Joleen J H, Vliet, Alex V, Baalen, Martijn V, Song, Ji-Ying, Guimaraes, Marcos Da Silva, Kuilman, Thomas, Peeper, Daniel S
Published in Molecular cancer research (01.05.2023)
Published in Molecular cancer research (01.05.2023)
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Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated Treg compartment
van der Leun, Anne M, Traets, Joleen J H, Vos, Joris L, Elbers, Joris B W, Patiwael, Sanne, Qiao, Xiaohang, Machuca-Ostos, Mercedes, Thommen, Daniela S, Haanen, John B A G, Schumacher, Ton N M, Zuur, Charlotte L
Published in Cancer discovery (05.10.2023)
Published in Cancer discovery (05.10.2023)
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Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness
Lin, Chun-Pu, Levy, Pierre L., Alflen, Astrid, Apriamashvili, Georgi, Ligtenberg, Maarten A., Vredevoogd, David W., Bleijerveld, Onno B., Alkan, Ferhat, Malka, Yuval, Hoekman, Liesbeth, Markovits, Ettai, George, Austin, Traets, Joleen J.H., Krijgsman, Oscar, van Vliet, Alex, Poźniak, Joanna, Pulido-Vicuña, Carlos Ariel, de Bruijn, Beaunelle, van Hal-van Veen, Susan E., Boshuizen, Julia, van der Helm, Pim W., Díaz-Gómez, Judit, Warda, Hamdy, Behrens, Leonie M., Mardesic, Paula, Dehni, Bilal, Visser, Nils L., Marine, Jean-Christophe, Markel, Gal, Faller, William J., Altelaar, Maarten, Agami, Reuven, Besser, Michal J., Peeper, Daniel S.
Published in Cancer cell (08.04.2024)
Published in Cancer cell (08.04.2024)
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An adverse tumor-protective effect of IDO1 inhibition
Kenski, Juliana C.N., Huang, Xinyao, Vredevoogd, David W., de Bruijn, Beaunelle, Traets, Joleen J.H., Ibáñez-Molero, Sofía, Schieven, Sebastiaan M., van Vliet, Alex, Krijgsman, Oscar, Kuilman, Thomas, Pozniak, Joanna, Loayza-Puch, Fabricio, Terry, Alexandra M., Müller, Judith, Logtenberg, Meike E.W., de Bruijn, Marjolein, Levy, Pierre, Körner, Pierre-René, Goding, Colin R., Schumacher, Ton N., Marine, Jean-Christophe, Agami, Reuven, Peeper, Daniel S.
Published in Cell reports. Medicine (21.02.2023)
Published in Cell reports. Medicine (21.02.2023)
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Mechanism of life-long maintenance of neuron identity despite molecular fluctuations
Traets, Joleen Jh, van der Burght, Servaas N, Rademakers, Suzanne, Jansen, Gert, van Zon, Jeroen S
Published in eLife (15.12.2021)
Published in eLife (15.12.2021)
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Diversity of the immune microenvironment and response to checkpoint inhibitor immunotherapy in mucosal melanoma
Vos, Joris L, Traets, Joleen Jh, Qiao, Xiaohang, Seignette, Iris M, Peters, Dennis, Wouters, Michel Wjm, Hooijberg, Erik, Broeks, Annegien, van der Wal, Jacqueline E, Karakullukcu, M Baris, Klop, W Martin C, Navran, Arash, van Beurden, Marc, Brouwer, Oscar R, Morris, Luc Gt, van Poelgeest, Mariette Ie, Kapiteijn, Ellen, Haanen, John Bag, Blank, Christian U, Zuur, Charlotte L
Published in JCI insight (08.11.2024)
Published in JCI insight (08.11.2024)
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High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer: e0138141
Broek, Evert vanden, Dijkstra, Maurits JJ, Krijgsman, Oscar, Sie, Daoud, Haan, Josien C, Traets, Joleen JH, Wiel, A vande, Nagtegaal, Iris D, Punt, Cornelis JA, Carvalho, Beatriz
Published in PloS one (01.09.2015)
Published in PloS one (01.09.2015)
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