KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington’s disease patients
Quinti, Luisa, Naidu, Sharadha Dayalan, Träger, Ulrike, Chen, Xiqun, Kegel-Gleason, Kimberly, Llères, David, Connolly, Colúm, Chopra, Vanita, Low, Cho, Moniot, Sébastien, Sapp, Ellen, Tousley, Adelaide R., Vodicka, Petr, Van Kanegan, Michael J., Kaltenbach, Linda S., Crawford, Lisa A., Fuszard, Matthew, Higgins, Maureen, Miller, James R. C., Farmer, Ruth E., Potluri, Vijay, Samajdar, Susanta, Meisel, Lisa, Zhang, Ningzhe, Snyder, Andrew, Stein, Ross, Hersch, Steven M., Ellerby, Lisa M., Weerapana, Eranthie, Schwarzschild, Michael A., Steegborn, Clemens, Leavitt, Blair R., Degterev, Alexei, Tabrizi, Sarah J., Lo, Donald C., DiFiglia, Marian, Thompson, Leslie M., Dinkova-Kostova, Albena T., Kazantsev, Aleksey G.
Published in Proceedings of the National Academy of Sciences - PNAS (06.06.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (06.06.2017)
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Journal Article
Rbpj expression in regulatory T cells is critical for restraining TH2 responses
Delacher, Michael, Schmidl, Christian, Herzig, Yonatan, Breloer, Minka, Hartmann, Wiebke, Brunk, Fabian, Kägebein, Danny, Träger, Ulrike, Hofer, Ann-Cathrin, Bittner, Sebastian, Weichenhan, Dieter, Imbusch, Charles D., Hotz-Wagenblatt, Agnes, Hielscher, Thomas, Breiling, Achim, Federico, Giuseppina, Gröne, Hermann-Josef, Schmid, Roland M., Rehli, Michael, Abramson, Jakub, Feuerer, Markus
Published in Nature communications (08.04.2019)
Published in Nature communications (08.04.2019)
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Journal Article
Mutant huntingtin impairs immune cell migration in Huntington disease
Kwan, Wanda, Träger, Ulrike, Davalos, Dimitrios, Chou, Austin, Bouchard, Jill, Andre, Ralph, Miller, Aaron, Weiss, Andreas, Giorgini, Flaviano, Cheah, Christine, Möller, Thomas, Stella, Nephi, Akassoglou, Katerina, Tabrizi, Sarah J, Muchowski, Paul J
Published in The Journal of clinical investigation (01.12.2012)
Published in The Journal of clinical investigation (01.12.2012)
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Journal Article
Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression
Weiss, Andreas, Träger, Ulrike, Wild, Edward J, Grueninger, Stephan, Farmer, Ruth, Landles, Christian, Scahill, Rachael I, Lahiri, Nayana, Haider, Salman, Macdonald, Douglas, Frost, Chris, Bates, Gillian P, Bilbe, Graeme, Kuhn, Rainer, Andre, Ralph, Tabrizi, Sarah J
Published in The Journal of clinical investigation (01.10.2012)
Published in The Journal of clinical investigation (01.10.2012)
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Journal Article
Characterisation of immune cell function in fragment and full-length Huntington's disease mouse models
Träger, Ulrike, Andre, Ralph, Magnusson-Lind, Anna, Miller, James R.C, Connolly, Colúm, Weiss, Andreas, Grueninger, Stephan, Silajdžić, Edina, Smith, Donna L, Leavitt, Blair R, Bates, Gillian P, Björkqvist, Maria, Tabrizi, Sarah J
Published in Neurobiology of disease (01.01.2015)
Published in Neurobiology of disease (01.01.2015)
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Journal Article
The immune response to melanoma is limited by thymic selection of self-antigens
Träger, Ulrike, Sierro, Sophie, Djordjevic, Gordana, Bouzo, Basma, Khandwala, Shivani, Meloni, Antonella, Mortensen, Monika, Simon, Anna Katharina
Published in PloS one (10.04.2012)
Published in PloS one (10.04.2012)
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Journal Article
Allele-Selective Suppression of Mutant Huntingtin in Primary Human Blood Cells
Miller, James R. C., Pfister, Edith L., Liu, Wanzhao, Andre, Ralph, Träger, Ulrike, Kennington, Lori A., Lo, Kimberly, Dijkstra, Sipke, Macdonald, Douglas, Ostroff, Gary, Aronin, Neil, Tabrizi, Sarah J.
Published in Scientific reports (24.04.2017)
Published in Scientific reports (24.04.2017)
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Journal Article
Mutant Huntingtin Does Not Affect the Intrinsic Phenotype of Human Huntington's Disease T Lymphocytes
Miller, James R C, Träger, Ulrike, Andre, Ralph, Tabrizi, Sarah J
Published in PloS one (03.11.2015)
Published in PloS one (03.11.2015)
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Journal Article
Quantitative Proteomics Identifies TCF1 as a Negative Regulator of Foxp3 Expression in Conventional T Cells
Delacher, Michael, Barra, Melanie M., Herzig, Yonatan, Eichelbaum, Katrin, Rafiee, Mahmoud-Reza, Richards, David M., Träger, Ulrike, Hofer, Ann-Cathrin, Kazakov, Alexander, Braband, Kathrin L., Gonzalez, Marina, Wöhrl, Lukas, Schambeck, Kathrin, Imbusch, Charles D., Abramson, Jakub, Krijgsveld, Jeroen, Feuerer, Markus
Published in iScience (22.05.2020)
Published in iScience (22.05.2020)
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Journal Article
Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
Delacher, Michael, Imbusch, Charles D, Weichenhan, Dieter, Breiling, Achim, Hotz-Wagenblatt, Agnes, Träger, Ulrike, Hofer, Ann-Cathrin, Kägebein, Danny, Wang, Qi, Frauhammer, Felix, Mallm, Jan-Philipp, Bauer, Katharina, Herrmann, Carl, Lang, Philipp A, Brors, Benedikt, Plass, Christoph, Feuerer, Markus
Published in Nature immunology (01.10.2017)
Published in Nature immunology (01.10.2017)
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Journal Article
Peripheral inflammation in neurodegeneration
Träger, Ulrike, Tabrizi, Sarah J.
Published in Journal of molecular medicine (Berlin, Germany) (01.06.2013)
Published in Journal of molecular medicine (Berlin, Germany) (01.06.2013)
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Journal Article
HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation
TRÄGER, Ulrike, ANDRE, Ralph, MOSER, Roger, HUMMERICH, Holger, ANTONIOU, Michael, BATES, Gillian P, LUTHI-CARTER, Ruth, LOWDELL, Mark W, BJÖRKQVIST, Maria, OSTROFF, Gary R, ARONIN, Neil, TABRIZI, Sarah J, LAHIRI, Nayana, MAGNUSSON-LIND, Anna, WEISS, Andreas, GRUENINGER, Stephan, MCKINNON, Chris, SIRINATHSINGHJI, Eva, KAHLON, Shira, PFISTER, Edith L
Published in Brain (London, England : 1878) (01.03.2014)
Published in Brain (London, England : 1878) (01.03.2014)
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Journal Article
RNA-Seq of Huntington's disease patient myeloid cells reveals innate transcriptional dysregulation associated with proinflammatory pathway activation
Miller, James R C, Lo, Kitty K, Andre, Ralph, Hensman Moss, Davina J, Träger, Ulrike, Stone, Timothy C, Jones, Lesley, Holmans, Peter, Plagnol, Vincent, Tabrizi, Sarah J
Published in Human molecular genetics (15.07.2016)
Published in Human molecular genetics (15.07.2016)
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Journal Article
Correction: Corrigendum: Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
Delacher, Michael, Imbusch, Charles D, Weichenhan, Dieter, Breiling, Achim, Hotz-Wagenblatt, Agnes, Träger, Ulrike, Hofer, Ann-Cathrin, Kägebein, Danny, Wang, Qi, Frauhammer, Felix, Mallm, Jan-Philipp, Bauer, Katharina, Herrmann, Carl, Lang, Philipp A, Brors, Benedikt, Plass, Christoph, Feuerer, Markus
Published in Nature immunology (01.12.2017)
Published in Nature immunology (01.12.2017)
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Journal Article
Corrigendum: Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
Delacher, Michael, Imbusch, Charles D, Weichenhan, Dieter, Breiling, Achim, Hotz-Wagenblatt, Agnes, Träger, Ulrike, Hofer, Ann-Cathrin, Kägebein, Danny, Wang, Qi, Frauhammer, Felix, Mallm, Jan-Philipp, Bauer, Katharina, Herrmann, Carl, Lang, Philipp A, Brors, Benedikt, Plass, Christoph, Feuerer, Markus
Published in Nature immunology (01.12.2017)
Published in Nature immunology (01.12.2017)
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Journal Article
Erratum: Corrigendum: Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
Delacher, Michael, Imbusch, Charles D, Weichenhan, Dieter, Breiling, Achim, Hotz-Wagenblatt, Agnes, Träger, Ulrike, Hofer, Ann-Cathrin, Kägebein, Danny, Wang, Qi, Frauhammer, Felix, Mallm, Jan-Philipp, Bauer, Katharina, Herrmann, Carl, Lang, Philipp A, Brors, Benedikt, Plass, Christoph, Feuerer, Markus
Published in Nature immunology (01.12.2017)
Published in Nature immunology (01.12.2017)
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Journal Article
B15 Innate transcriptional dysregulation is associated with proinflammatory pathway activation in huntington’s disease myeloid cells
Andre, Ralph, Miller, James RC, Lo, Kitty K, Hensman Moss, Davina J, Träger, Ulrike, Stone, Timothy C, McErlean, Peter, Jones, Lesley, Holmans, Peter, Lavender, Paul, Plagnol, Vincent, Tabrizi, Sarah J
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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