S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation
Toyomoto, Masayasu, Inoue, Asuka, Iida, Kei, Denawa, Masatsugu, Kii, Isao, Ngako Kadji, Francois Marie, Kishi, Takayuki, Im, Dohyun, Shimamura, Tatsuro, Onogi, Hiroshi, Yoshida, Suguru, Iwata, So, Aoki, Junken, Hosoya, Takamitsu, Hagiwara, Masatoshi
Published in Cell chemical biology (19.08.2021)
Published in Cell chemical biology (19.08.2021)
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Journal Article
Hydroxypropyl Cyclodextrin Improves Amiodarone-induced Aberrant Lipid Homeostasis of Alveolar Cells
Kanagaki, Shuhei, Suezawa, Takahiro, Moriguchi, Keita, Nakao, Kazuhisa, Toyomoto, Masayasu, Yamamoto, Yuki, Murakami, Koji, Hagiwara, Masatoshi, Gotoh, Shimpei
Published in American journal of respiratory cell and molecular biology (01.04.2021)
Published in American journal of respiratory cell and molecular biology (01.04.2021)
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Journal Article
Actin-binding protein coronin 1A controls osteoclastic bone resorption by regulating lysosomal secretion of cathepsin K
Ohmae, Saori, Noma, Naruto, Toyomoto, Masayasu, Shinohara, Masahiro, Takeiri, Masatoshi, Fuji, Hiroaki, Takemoto, Kenji, Iwaisako, Keiko, Fujita, Tomoko, Takeda, Norihiko, Kawatani, Makoto, Aoyama, Mineyoshi, Hagiwara, Masatoshi, Ishihama, Yasushi, Asagiri, Masataka
Published in Scientific reports (16.03.2017)
Published in Scientific reports (16.03.2017)
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Journal Article
Alleviation of Behavioral Hypersensitivity in Mouse Models of Inflammatory Pain with Two Structurally Different Casein Kinase 1 (CK1) Inhibitors
Kurihara, Takashi, Sakurai, Eri, Toyomoto, Masayasu, Kii, Isao, Kawamoto, Daisuke, Asada, Toshihide, Tanabe, Tsutomu, Yoshimura, Megumu, Hagiwara, Masatoshi, Miyata, Atsuro
Published in Molecular pain (10.03.2014)
Published in Molecular pain (10.03.2014)
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Journal Article
Anti-arthritic effect of E3 ubiquitin ligase, c-MIR, expression in the joints
Toyomoto, Masayasu, Ishido, Satoshi, Miyasaka, Nobuyuki, Sugimoto, Hachiro, Kohsaka, Hitoshi
Published in International immunology (01.03.2011)
Published in International immunology (01.03.2011)
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Journal Article
Hydroxypropyl Cyclodextrin Improves Amiodarone-induced Aberrant Lipid Homeostasis of Alveolar Cells
Kanagaki, Shuhei, Suezawa, Takahiro, Moriguchi, Keita, Nakao, Kazuhisa, Toyomoto, Masayasu, Yamamoto, Yuki, Murakami, Koji, Hagiwara, Masatoshi, Gotoh, Shimpei
Published in American journal of respiratory cell and molecular biology (01.04.2021)
Published in American journal of respiratory cell and molecular biology (01.04.2021)
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Journal Article
Disease modeling of pulmonary fibrosis using human pluripotent stem cell-derived alveolar organoids
Suezawa, Takahiro, Kanagaki, Shuhei, Moriguchi, Keita, Masui, Atsushi, Nakao, Kazuhisa, Toyomoto, Masayasu, Tamai, Koji, Mikawa, Ryuta, Hirai, Toyohiro, Murakami, Koji, Hagiwara, Masatoshi, Gotoh, Shimpei
Published in Stem cell reports (14.12.2021)
Published in Stem cell reports (14.12.2021)
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Journal Article
Development of an orally available inhibitor of CLK1 for skipping a mutated dystrophin exon in Duchenne muscular dystrophy
Sako, Yukiya, Ninomiya, Kensuke, Okuno, Yukiko, Toyomoto, Masayasu, Nishida, Atsushi, Koike, Yuka, Ohe, Kenji, Kii, Isao, Yoshida, Suguru, Hashimoto, Naohiro, Hosoya, Takamitsu, Matsuo, Masafumi, Hagiwara, Masatoshi
Published in Scientific reports (30.05.2017)
Published in Scientific reports (30.05.2017)
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Journal Article
Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis
Murakami, Yousuke, Akahoshi, Tohru, Aoki, Naoko, Toyomoto, Masayasu, Miyasaka, Nobuyuki, Kohsaka, Hitoshi
Published in Arthritis and rheumatism (01.06.2009)
Published in Arthritis and rheumatism (01.06.2009)
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Journal Article
Endogenous agonist–bound S1PR3 structure reveals determinants of G protein–subtype bias
Maeda, Shintaro, Shiimura, Yuki, Asada, Hidetsugu, Hirata, Kunio, Luo, Fangjia, Nango, Eriko, Tanaka, Nobuo, Toyomoto, Masayasu, Inoue, Asuka, Aoki, Junken, Iwata, So, Hagiwara, Masatoshi
Published in Science advances (01.06.2021)
Published in Science advances (01.06.2021)
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Journal Article
Necrostatin-7 suppresses RANK-NFATc1 signaling and attenuates macrophage to osteoclast differentiation
Fuji, Hiroaki, Ohmae, Saori, Noma, Naruto, Takeiri, Masatoshi, Yasutomi, Hideto, Izumi, Kazuya, Ito, Moe, Toyomoto, Masayasu, Iwaki, Soichiro, Takemoto, Kenji, Seo, Satoru, Taura, Kojiro, Hida, Shigeaki, Aoyama, Mineyoshi, Ishihama, Yasushi, Hagiwara, Masatoshi, Takeda, Norihiko, Hatano, Etsuro, Iwaisako, Keiko, Uemoto, Shinji, Asagiri, Masataka
Published in Biochemical and biophysical research communications (05.09.2018)
Published in Biochemical and biophysical research communications (05.09.2018)
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Journal Article
PHARMACEUTICAL COMPOSITION FOR INDUCING PROGRAMMED CELL DEATH IN CANCER CELLS
HOSOYA Takamitsu, YOSHIDA Suguru, HAGIWARA Masatoshi, TOYOMOTO Masayasu
Year of Publication 03.05.2018
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Year of Publication 03.05.2018
Patent
COMPOSITION HAVING COMPOUND ACCELERATING PHOSPHORYLATION OF AMPK AS EFFECTIVE COMPONENT
KII Isao, HOSOYA Takamitsu, YOSHIDA Suguru, HAGIWARA Masatoshi, TOYOMOTO Masayasu
Year of Publication 03.11.2016
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Year of Publication 03.11.2016
Patent
PAIN-RELATED COMPOUND AND MEDICINAL COMPOSITION
KURIHARA TAKASHI, HOSOYA TAKAMITSU, HAGIWARA MASATOSHI, TOYOMOTO MASAYASU, YOSHIDA SUGURU
Year of Publication 25.06.2015
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Year of Publication 25.06.2015
Patent