Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes
Lewis, Myles J., Barnes, Michael R., Blighe, Kevin, Goldmann, Katriona, Rana, Sharmila, Hackney, Jason A., Ramamoorthi, Nandhini, John, Christopher R., Watson, David S., Kummerfeld, Sarah K., Hands, Rebecca, Riahi, Sudeh, Rocher-Ros, Vidalba, Rivellese, Felice, Humby, Frances, Kelly, Stephen, Bombardieri, Michele, Ng, Nora, DiCicco, Maria, van der Heijde, Désirée, Landewé, Robert, van der Helm-van Mil, Annette, Cauli, Alberto, McInnes, Iain B., Buckley, Christopher D., Choy, Ernest, Taylor, Peter C., Townsend, Michael J., Pitzalis, Costantino
Published in Cell reports (Cambridge) (27.08.2019)
Published in Cell reports (Cambridge) (27.08.2019)
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Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration
Orozco, Luz D., Chen, Hsu-Hsin, Cox, Christian, Katschke, Kenneth J., Arceo, Rommel, Espiritu, Carmina, Caplazi, Patrick, Nghiem, Sarajane Saturnio, Chen, Ying-Jiun, Modrusan, Zora, Dressen, Amy, Goldstein, Leonard D., Clarke, Christine, Bhangale, Tushar, Yaspan, Brian, Jeanne, Marion, Townsend, Michael J., van Lookeren Campagne, Menno, Hackney, Jason A.
Published in Cell reports (Cambridge) (28.01.2020)
Published in Cell reports (Cambridge) (28.01.2020)
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Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC)
Lliso-Ribera, Gloria, Humby, Frances, Lewis, Myles, Nerviani, Alessandra, Mauro, Daniele, Rivellese, Felice, Kelly, Stephen, Hands, Rebecca, Bene, Fabiola, Ramamoorthi, Nandhini, Hackney, Jason A, Cauli, Alberto, Choy, Ernest H, Filer, Andrew, Taylor, Peter C, McInnes, Iain, Townsend, Michael J, Pitzalis, Costantino
Published in Annals of the rheumatic diseases (01.12.2019)
Published in Annals of the rheumatic diseases (01.12.2019)
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Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in systemic lupus erythematosus
Tokuyama, Maria, Gunn, Bronwyn M, Venkataraman, Arvind, Kong, Yong, Kang, Insoo, Rakib, Tasfia, Townsend, Michael J, Costenbader, Karen H, Alter, Galit, Iwasaki, Akiko
Published in The Journal of experimental medicine (05.07.2021)
Published in The Journal of experimental medicine (05.07.2021)
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NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus
Brightbill, Hans D., Suto, Eric, Blaquiere, Nicole, Ramamoorthi, Nandhini, Sujatha-Bhaskar, Swathi, Gogol, Emily B., Castanedo, Georgette M., Jackson, Benjamin T., Kwon, Youngsu C., Haller, Susan, Lesch, Justin, Bents, Karin, Everett, Christine, Kohli, Pawan Bir, Linge, Sandra, Christian, Laura, Barrett, Kathy, Jaochico, Allan, Berezhkovskiy, Leonid M., Fan, Peter W., Modrusan, Zora, Veliz, Kelli, Townsend, Michael J., DeVoss, Jason, Johnson, Adam R., Godemann, Robert, Lee, Wyne P., Austin, Cary D., McKenzie, Brent S., Hackney, Jason A., Crawford, James J., Staben, Steven T., Alaoui Ismaili, Moulay H., Wu, Lawren C., Ghilardi, Nico
Published in Nature communications (12.01.2018)
Published in Nature communications (12.01.2018)
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transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
Jenner, Richard G, Townsend, Michael J, Jackson, Ian, Sun, Kaiming, Bouwman, Russell D, Young, Richard A, Glimcher, Laurie H, Lord, Graham M
Published in Proceedings of the National Academy of Sciences - PNAS (20.10.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (20.10.2009)
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Ability of Interleukin‐33– and Immune Complex–Triggered Activation of Human Mast Cells to Down‐Regulate Monocyte‐Mediated Immune Responses
Rivellese, Felice, Suurmond, Jolien, Habets, Kim, Dorjée, Annemarie L., Ramamoorthi, Nandhini, Townsend, Michael J., de Paulis, Amato, Marone, Gianni, Huizinga, Tom W. J., Pitzalis, Costantino, Toes, René E. M.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2015)
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Promising bone-related therapeutic targets for rheumatoid arthritis
Choi, Yongwon, Arron, Joseph R, Townsend, Michael J
Published in Nature reviews. Rheumatology (01.10.2009)
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The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation
Senger, Kate, Pham, Victoria C, Varfolomeev, Eugene, Hackney, Jason A, Corzo, Cesar A, Collier, Jenna, Lau, Vivian W C, Huang, Zhiyu, Hamidzhadeh, Kajal, Caplazi, Patrick, Peng, Ivan, Setiadi, A Francesca, Francis, Ross, Paler-Martinez, Andres, Kwon, Youngsu C, Ramirez-Carrozzi, Vladimir, Sun, Yonglian, Grigg, Patricia W, Roose-Girma, Merone, Jeet, Surinder, Barck, Kai H, Pham, Anna, Ota, Naruhisa, Ha, Connie, Stinson, Jeremy, Guillory, Joseph, Tam, Lucinda, Modrusan, Zora, Emson, Claire, McKenzie, Brent S, Townsend, Michael J, Carano, Richard A D, Warming, Søren, Vucic, Domagoj, DeVoss, Jason, Lee, Wyne P, Lill, Jennie R, Zarrin, Ali A
Published in Science signaling (18.04.2017)
Published in Science signaling (18.04.2017)
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Journal Article
Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration
Orozco, Luz D., Chen, Hsu-Hsin, Cox, Christian, Katschke, Kenneth J., Rommel Arceo, Espiritu, Carmina, Caplazi, Patrick, Nghiem, Sarajane Saturnio, Chen, Ying-Jiun, Modrusan, Zora, Dressen, Amy, Goldstein, Leonard D., Clarke, Christine, Bhangale, Tushar, Yaspan, Brian, Jeanne, Marion, Townsend, Michael J., van Lookeren Campagne, Menno, Hackney, Jason A.
Published in Cell reports (Cambridge) (28.03.2023)
Published in Cell reports (Cambridge) (28.03.2023)
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Modular Analysis of Peripheral Blood Gene Expression in Rheumatoid Arthritis Captures Reproducible Gene Expression Changes in Tumor Necrosis Factor Responders
Oswald, Michaela, Curran, Mark E., Lamberth, Sarah L., Townsend, Robert M., Hamilton, Jennifer D., Chernoff, David N., Carulli, John, Townsend, Michael J., Weinblatt, Michael E., Kern, Marlena, Pond, Cassandra M., Lee, Annette, Gregersen, Peter K.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2015)
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Efficacy and safety of pateclizumab (anti-lymphotoxin-α) compared to adalimumab in rheumatoid arthritis: a head-to-head phase 2 randomized controlled study (The ALTARA Study)
Kennedy, William P, Simon, J Abraham, Offutt, Carolyn, Horn, Priscilla, Herman, Ann, Townsend, Michael J, Tang, Meina T, Grogan, Jane L, Hsieh, Frank, Davis, John C
Published in Arthritis research & therapy (30.10.2014)
Published in Arthritis research & therapy (30.10.2014)
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Characterization of IL-17AA and IL-17FF in rheumatoid arthritis and multiple sclerosis
Schofield, Cheryl, Fischer, Saloumeh K, Townsend, Michael J, Mosesova, Sofia, Peng, Kun, Setiadi, Alvernia Francesca, Song, An, Baruch, Amos
Published in Bioanalysis (01.11.2016)
Published in Bioanalysis (01.11.2016)
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Levels of CXCL13 and sICAM-1 correlate with disease activity score in patients with rheumatoid arthritis treated with tocilizumab
Tuckwell, Katie, Gabay, Cem, Sornasse, Thierry, Laubender, Ruediger Paul, Wang, Jianmei, Townsend, Michael J
Published in Advances in rheumatology (London, England) (04.12.2019)
Published in Advances in rheumatology (London, England) (04.12.2019)
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IL-4 Induces Characteristic Th2 Responses Even in the Combined Absence of IL-5, IL-9, and IL-13
Fallon, Padraic G., Jolin, Helen E., Smith, Philippa, Emson, Claire L., Townsend, Michael J., Fallon, Rosie, Smith, Philip, McKenzie, Andrew N.J.
Published in Immunity (Cambridge, Mass.) (01.07.2002)
Published in Immunity (Cambridge, Mass.) (01.07.2002)
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SIGN-R1 contributes to protection against lethal pneumococcal infection in mice
Lanoue, Astrid, Clatworthy, Menna R, Smith, Philippa, Green, Sheila, Townsend, Michael J, Jolin, Helen E, Smith, Kenneth G C, Fallon, Padraic G, McKenzie, Andrew N J
Published in The Journal of experimental medicine (06.12.2004)
Published in The Journal of experimental medicine (06.12.2004)
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Distal regions of the human IFNG locus direct cell type-specific expression
Collins, Patrick L, Chang, Shaojing, Henderson, Melodie, Soutto, Mohammed, Davis, Georgia M, McLoed, Allyson G, Townsend, Michael J, Glimcher, Laurie H, Mortlock, Douglas P, Aune, Thomas M
Published in The Journal of immunology (1950) (01.08.2010)
Published in The Journal of immunology (1950) (01.08.2010)
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Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients
Humby, Frances, Lewis, Myles, Ramamoorthi, Nandhini, Hackney, Jason A, Barnes, Michael R, Bombardieri, Michele, Setiadi, A. Francesca, Kelly, Stephen, Bene, Fabiola, DiCicco, Maria, Riahi, Sudeh, Rocher, Vidalba, Ng, Nora, Lazarou, Ilias, Hands, Rebecca, van der Heijde, Désirée, Landewé, Robert B M, van der Helm-van Mil, Annette, Cauli, Alberto, McInnes, Iain, Buckley, Christopher Dominic, Choy, Ernest H, Taylor, Peter C, Townsend, Michael J, Pitzalis, Costantino
Published in Annals of the rheumatic diseases (01.06.2019)
Published in Annals of the rheumatic diseases (01.06.2019)
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