Essential role for centromeric factors following p53 loss and oncogenic transformation
Filipescu, Dan, Naughtin, Monica, Podsypanina, Katrina, Lejour, Vincent, Wilson, Laurence, Gurard-Levin, Zachary A, Orsi, Guillermo A, Simeonova, Iva, Toufektchan, Eleonore, Attardi, Laura D, Toledo, Franck, Almouzni, Geneviève
Published in Genes & development (01.03.2017)
Published in Genes & development (01.03.2017)
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Journal Article
ER-directed TREX1 limits cGAS activation at micronuclei
Mohr, Lisa, Toufektchan, Eléonore, von Morgen, Patrick, Chu, Kevan, Kapoor, Aakanksha, Maciejowski, John
Published in Molecular cell (18.02.2021)
Published in Molecular cell (18.02.2021)
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Journal Article
p53 downregulates the Fanconi anaemia DNA repair pathway
Jaber, Sara, Toufektchan, Eléonore, Lejour, Vincent, Bardot, Boris, Toledo, Franck
Published in Nature communications (01.04.2016)
Published in Nature communications (01.04.2016)
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Journal Article
Epigenetic dysregulation from chromosomal transit in micronuclei
Agustinus, Albert S., Al-Rawi, Duaa, Dameracharla, Bhargavi, Raviram, Ramya, Jones, Bailey S. C. L., Stransky, Stephanie, Scipioni, Lorenzo, Luebeck, Jens, Di Bona, Melody, Norkunaite, Danguole, Myers, Robert M., Duran, Mercedes, Choi, Seongmin, Weigelt, Britta, Yomtoubian, Shira, McPherson, Andrew, Toufektchan, Eléonore, Keuper, Kristina, Mischel, Paul S., Mittal, Vivek, Shah, Sohrab P., Maciejowski, John, Storchova, Zuzana, Gratton, Enrico, Ly, Peter, Landau, Dan, Bakhoum, Mathieu F., Koche, Richard P., Sidoli, Simone, Bafna, Vineet, David, Yael, Bakhoum, Samuel F.
Published in Nature (London) (06.07.2023)
Published in Nature (London) (06.07.2023)
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Journal Article
APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis
Maciejowski, John, Chatzipli, Aikaterini, Dananberg, Alexandra, Chu, Kevan, Toufektchan, Eleonore, Klimczak, Leszek J., Gordenin, Dmitry A., Campbell, Peter J., de Lange, Titia
Published in Nature genetics (01.09.2020)
Published in Nature genetics (01.09.2020)
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Journal Article
Germline mutation of MDM4 , a major p53 regulator, in a familial syndrome of defective telomere maintenance
Toufektchan, Eléonore, Lejour, Vincent, Durand, Romane, Giri, Neelam, Draskovic, Irena, Bardot, Boris, Laplante, Pierre, Jaber, Sara, Alter, Blanche P, Londono-Vallejo, José-Arturo, Savage, Sharon A, Toledo, Franck
Published in Science advances (01.04.2020)
Published in Science advances (01.04.2020)
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Journal Article
Abstract 4293: Chromosomal instability causes epigenetic aberrations in cancer
Agustinus, Albert S., Al-Rawi, Duaa, Dameracharla, Bhargavi, Raviram, Ramya, Jones, Bailey S., Stransky, Stephanie, Scipioni, Lorenzo, Luebeck, Jens, Bona, Melody Di, Norkunaite, Danguole, Myers, Robert M., Duran, Mercedes, Choi, Seongmin, Weigelt, Britta, Yomtoubian, Shira, McPherson, Andrew, Toufektchan, Eleonore, Keuper, Kristina, Mischel, Paul S., Mittal, Vivek, Shah, Sohrab P., Maciejowski, John, Storchova, Zuzana, Gratton, Enrico, Ly, Peter, Landau, Dan, Bakhoum, Mathieu F., Koche, Richard P., Sidoli, Simone, Bafna, Vineet, David, Yael, Bakhoum, Samuel F.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract 3768: Epigenetic dysregulation from chromosomal transit in micronuclei
Agustinus, Albert S., Raviram, Ramya, Dameracharla, Bhargavi, Luebeck, Jens, Stransky, Stephanie, Scipioni, Lorenzo, Myers, Robert M., Bona, Melody Di, Duran, Mercedes, Weigelt, Britta, Yomtoubian, Shira, Toufektchan, Eleonore, Mischel, Paul S., Mittal, Vivek, Shah, Sohrab, Maciejowski, John, Gratton, Enrico, Ly, Peter, Bakhoum, Mathieu F., Landau, Dan, Bafna, Vineet, Sidoli, Simone, David, Yael, Bakhoum, Samuel F.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
p53 downregulates the Fanconi anaemia DNA repair pathway
Jaber, Sara, Toufektchan, Eléonore, Lejour, Vincent, Bardot, Boris, Toledo, Franck
Published in Nature communications (01.04.2016)
Published in Nature communications (01.04.2016)
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Journal Article
TREX1 restricts CRISPR-Cas9 genome editing in human cells
Mehmet Erman Karasu, Toufektchan, Eleonore, Maciejowski, John, Corn, Jacob E
Published in bioRxiv (13.12.2022)
Published in bioRxiv (13.12.2022)
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Paper
Intratumoral TREX1 induction promotes immune evasion by limiting type I interferon
Toufektchan, Eléonore, Dananberg, Alexandra, Striepen, Josefine, Hickling, James H, Shim, Abraham, Chen, Yanyang, Nichols, Ashley, Duran Paez, Mercedes A, Mohr, Lisa, Bakhoum, Samuel F, Maciejowski, John
Published in Cancer immunology research (26.02.2024)
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Published in Cancer immunology research (26.02.2024)
Journal Article
ER-directed TREX1 limits cGAS recognition of micronuclei
Mohr, Lisa, Toufektchan, Eleonore, Chu, Kevan H, Maciejowski, John
Published in bioRxiv (20.05.2020)
Published in bioRxiv (20.05.2020)
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Paper
Germline mutation of MDM4 , a major p53 regulator, in a familial syndrome of defective telomere maintenance
Toufektchan, Eléonore, Lejour, Vincent, Durand, Romane, Giri, Neelam, Draskovic, Irena, Bardot, Boris, Laplante, Pierre, Jaber, Sara, Alter, Blanche, Londono-Vallejo, José-Arturo, Savage, Sharon, Toledo, Franck
Published in Science advances (10.04.2020)
Published in Science advances (10.04.2020)
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