Synthesis and pharmacological evaluation of sulfone substituted HIV protease inhibitors
Schwartz, Theresa M., Bundy, Gordon L., Strohbach, Joseph W., Thaisrivongs, Suvit, Johnson, Paul D., Skulnick, Harvey I., Tomich, Paul K., Lynn, Janet C., Chong, Kong Teck, Hinshaw, Roger R., Raub, Thomas J., Padbury, Guy E., Toth, Lisa N.
Published in Bioorganic & medicinal chemistry letters (18.02.1997)
Published in Bioorganic & medicinal chemistry letters (18.02.1997)
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Structure-Based Design of HIV Protease Inhibitors: 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Non-peptidic Inhibitors
Thaisrivongs, Suvit, Tomich, Paul K, Watenpaugh, Keith D, Chong, Kong-Teck, Howe, W. Jeffrey, Yang, Chih-Ping, Strohbach, Joseph W, Turner, Steve R, McGrath, James P
Published in Journal of medicinal chemistry (01.09.1994)
Published in Journal of medicinal chemistry (01.09.1994)
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Use of Medium-Sized Cycloalkyl Rings To Enhance Secondary Binding: Discovery of a New Class of Human Immunodeficiency Virus (HIV) Protease Inhibitors
Romines, Karen R, Watenpaugh, Keith D, Tomich, Paul K, Howe, W. Jeffrey, Morris, Jeanette K, Lovasz, Kristine D, Mulichak, Anne M, Finzel, Barry C, Lynn, Janet C
Published in Journal of medicinal chemistry (01.05.1995)
Published in Journal of medicinal chemistry (01.05.1995)
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STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS
THAISRIVONGS, S, TOMICH, PK, WATENPAUGH, KD, CHONG, KT, HOWE, WJ, YANG, CP, STROHBACH, JW, TURNER, MCGRATH, JP, BOHANON, MJ, LYNN, JC, MULICHAK, AM, SPINELLI, PA, HINSHAW, RR, PAGANO, PJ, MOON, JB, RUWART, MJ, WILKINSON, KF, RUSH, BD, ZIPP, GL, DALGA, RJ, SCHWENDE, FJ, HOWARD, GM, PADBURY, GE, TOTH, LN, ZHAO, ZY, KOEPLINGER, KA, KAKUK, TJ, COLE, SL, ZAYA, RM, PIPER, RC, JEFFREY, P
Published in Journal of medicinal chemistry (30.09.1994)
Published in Journal of medicinal chemistry (30.09.1994)
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COMPARISON OF PREDICTION METHODS FOR IN VIVO CLEARANCE OF (S,S)-3-[3-(METHYLSULFONYL)PHENYL]-1-PROPYLPIPERIDINE HYDROCHLORIDE, A DOPAMINE D2 RECEPTOR ANTAGONIST, IN HUMANS
YAMAZAKI, Shinji, TOTH, Lisa N, BLACK, Meredith L, DUNCAN, J. Neil
Published in Drug metabolism and disposition (01.04.2004)
Published in Drug metabolism and disposition (01.04.2004)
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Structure-based design of nonpeptidic HIV protease inhibitors: the sulfonamide-substituted cyclooctylpyramones
Skulnick, H I, Johnson, P D, Aristoff, P A, Morris, J K, Lovasz, K D, Howe, W J, Watenpaugh, K D, Janakiraman, M N, Anderson, D J, Reischer, R J, Schwartz, T M, Banitt, L S, Tomich, P K, Lynn, J C, Horng, M M, Chong, K T, Hinshaw, R R, Dolak, L A, Seest, E P, Schwende, F J, Rush, B D, Howard, G M, Toth, L N, Wilkinson, K R, Romines, K R
Published in Journal of medicinal chemistry (28.03.1997)
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Published in Journal of medicinal chemistry (28.03.1997)
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