TLR5 agonist entolimod reduces the adverse toxicity of TNF while preserving its antitumor effects
Haderski, Gary J, Kandar, Bojidar M, Brackett, Craig M, Toshkov, Ilia M, Johnson, Christopher P, Paszkiewicz, Geraldine M, Natarajan, Venkatesh, Gleiberman, Anatoli S, Gudkov, Andrei V, Burdelya, Lyudmila G
Published in PloS one (06.02.2020)
Published in PloS one (06.02.2020)
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The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates
Krivokrysenko, Vadim I, Toshkov, Ilia A, Gleiberman, Anatoli S, Krasnov, Peter, Shyshynova, Inna, Bespalov, Ivan, Maitra, Ratan K, Narizhneva, Natalya V, Singh, Vijay K, Whitnall, Mark H, Purmal, Andrei A, Shakhov, Alexander N, Gudkov, Andrei V, Feinstein, Elena
Published in PloS one (14.09.2015)
Published in PloS one (14.09.2015)
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OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis
Korotchkina, Lioubov, Kazyulkin, Denis, Komarov, Pavel G, Polinsky, Alex, Andrianova, Ekaterina L, Joshi, Sangeeta, Gupta, Mahima, Vujcic, Slavoljub, Kononov, Eugene, Toshkov, Ilia, Tian, Yuan, Krasnov, Peter, Chernov, Mikhail V, Veith, Jean, Antoch, Marina P, Middlemiss, Shiloh, Somers, Klaartje, Lock, Richard B, Norris, Murray D, Henderson, Michelle J, Haber, Michelle, Chernova, Olga B, Gudkov, Andrei V
Published in Leukemia (01.07.2020)
Published in Leukemia (01.07.2020)
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A deimmunized and pharmacologically optimized Toll-like receptor 5 agonist for therapeutic applications
Mett, Vadim, V Kurnasov, Oleg, A Bespalov, Ivan, Molodtsov, Ivan, M Brackett, Craig, G Burdelya, Lyudmila, A Purmal, Andrei, S Gleiberman, Anatoli, A Toshkov, Ilia, A Burkhart, Catherine, N Kogan, Yakov, L Andrianova, Ekaterina, V Gudkov, Andrei, L Osterman, Andrei
Published in Communications biology (12.04.2021)
Published in Communications biology (12.04.2021)
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Mitigation of Radiation-Induced Epithelial Damage by the TLR5 Agonist Entolimod in a Mouse Model of Fractionated Head and Neck Irradiation
Toshkov, Ilia A, Gleiberman, Anatoli S, Mett, Vadim L, Hutson, Alan D, Singh, Anurag K, Gudkov, Andrei V, Burdelya, Lyudmila G
Published in Radiation research (01.05.2017)
Published in Radiation research (01.05.2017)
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Toll-like Receptor 5 Agonist Protects Mice From Dermatitis and Oral Mucositis Caused by Local Radiation: Implications for Head-and-Neck Cancer Radiotherapy
Burdelya, Lyudmila G., Ph.D, Gleiberman, Anatoli S., Ph.D, Toshkov, Ilia, M.D., Ph.D, Aygun-Sunar, Semra, Ph.D, Bapardekar, Meghana, Ph.D, Manderscheid-Kern, Patricia, Ph.D, Bellnier, David, Ph.D, Krivokrysenko, Vadim I., Ph.D, Feinstein, Elena, M.D., Ph.D, Gudkov, Andrei V., Ph.D., D.Sci
Published in International journal of radiation oncology, biology, physics (01.05.2012)
Published in International journal of radiation oncology, biology, physics (01.05.2012)
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Toll-like receptor-5 agonist Entolimod broadens the therapeutic window of 5-fluorouracil by reducing its toxicity to normal tissues in mice
Kojouharov, Bojidar M, Brackett, Craig M, Veith, Jean M, Johnson, Christopher P, Gitlin, Ilya I, Toshkov, Ilia A, Gleiberman, Anatoli S, Gudkov, Andrei V, Burdelya, Lyudmila G
Published in Oncotarget (15.02.2014)
Published in Oncotarget (15.02.2014)
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Hepatocellular carcinoma in the woodchuck model of hepatitis B virus infection
Tennant, Bud C, Toshkov, Ilia A, Peek, Simon F, Jacob, James R, Menne, Stephan, Hornbuckle, William E, Schinazi, Raymond D, Korba, Brent E, Cote, Paul J, Gerin, John L
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2004)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2004)
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Antiviral activity of clevudine [ L-FMAU, (1-(2-fluoro-5-methyl-β, L-arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks ( Marmota monax)
Peek, Simon F., Cote, Paul J., Jacob, James R., Toshkov, Ilia A., Hornbuckle, William E., Baldwin, Betty H., Wells, Frances V., Chu, C.K., Gerin, John L., Tennant, Bud C., Korba, Brent E.
Published in Hepatology (Baltimore, Md.) (2001)
Published in Hepatology (Baltimore, Md.) (2001)
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Integration of woodchuck hepatitis and N‐myc rearrangement determine size and histologic grade of hepatic tumors
Jacob, James R., Sterczer, Agnes, Toshkov, Ilia A., Yeager, Amy E., Korba, Brent E., Cote, Paul J., Buendia, Marie‐Annick, Gerin, John L., Tennant, Bud C.
Published in Hepatology (Baltimore, Md.) (01.04.2004)
Published in Hepatology (Baltimore, Md.) (01.04.2004)
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New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53-/- mice by delaying carcinogenesis
Comas, Maria, Toshkov, Ilia, Kuropatwinski, Karen K, Chernova, Olga B, Polinsky, Alexander, Blagosklonny, Mikhail V, Gudkov, Andrei V, Antoch, Marina P
Published in Aging (Albany, NY.) (01.10.2012)
Published in Aging (Albany, NY.) (01.10.2012)
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Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice
Antoch, Marina P, Wrobel, Michelle, Kuropatwinski, Karen K, Gitlin, Ilya, Leonova, Katerina I, Toshkov, Ilia, Gleiberman, Anatoli S, Hutson, Alan D, Chernova, Olga B, Gudkov, Andrei V
Published in Aging (Albany, NY.) (19.03.2017)
Published in Aging (Albany, NY.) (19.03.2017)
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Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer
Antoch, Marina P, Wrobel, Michelle, Gillard, Bryan, Kuropatwinski, Karen K, Toshkov, Ilia, Gleiberman, Anatoli S, Karasik, Ellen, Moser, Michael T, Foster, Barbara A, Andrianova, Ekaterina L, Chernova, Olga V, Gudkov, Andrei V
Published in Oncotarget (14.04.2020)
Published in Oncotarget (14.04.2020)
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Abstract 4946: Developing anti-angiogenic therapies for human hepatocellular cancer (HCC)- studies of suntinib in the woodchuck model of hepatitis B related HCC
Pomakov, Alexander, Toshkov, Ilia, Buitrago, Sandra, Curtin, Leslie, Trump, Donald, Johnson, Candace, Ashton, Edward, Tennant, Bud, Iyer, Renuka
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract 5144: Low dose sorafenib delays hepatocellular cancer (HCC) development in the woodchuck model of hepatitis B related HCC
Iyer, Renuka V., Sexton, Sandra, Curtin, Leslie, Fetterly, Gerald, Maguire, Orla, Minderman, Hans, Toshkov, Ilia, Tennant, Bud, Hutson, Alan, Trump, Donald L., Johnson, Candace
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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