A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke
Yamazawa, Toshiko, Kobayashi, Takuya, Kurebayashi, Nagomi, Konishi, Masato, Noguchi, Satoru, Inoue, Takayoshi, Inoue, Yukiko U., Nishino, Ichizo, Mori, Shuichi, Iinuma, Hiroto, Manaka, Noriaki, Kagechika, Hiroyuki, Uryash, Arkady, Adams, Jose, Lopez, Jose R., Liu, Xiaochen, Diggle, Christine, Allen, Paul D., Kakizawa, Sho, Ikeda, Keigo, Lin, Bangzhong, Ikemi, Yui, Nunomura, Kazuto, Nakagawa, Shinsaku, Sakurai, Takashi, Murayama, Takashi
Published in Nature communications (13.07.2021)
Published in Nature communications (13.07.2021)
Get full text
Journal Article
Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating
Oyama, Kotaro, Zeeb, Vadim, Yamazawa, Toshiko, Kurebayashi, Nagomi, Kobirumaki-Shimozawa, Fuyu, Murayama, Takashi, Oyamada, Hideto, Noguchi, Satoru, Inoue, Takayoshi, Inoue, Yukiko U., Nishino, Ichizo, Harada, Yoshie, Fukuda, Norio, Ishiwata, Shin’ichi, Suzuki, Madoka
Published in Proceedings of the National Academy of Sciences - PNAS (09.08.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (09.08.2022)
Get full text
Journal Article
Genotype-Phenotype Correlations of Malignant Hyperthermia and Central Core Disease Mutations in the Central Region of the RYR1 Channel
Murayama, Takashi, Kurebayashi, Nagomi, Ogawa, Haruo, Yamazawa, Toshiko, Oyamada, Hideto, Suzuki, Junji, Kanemaru, Kazunori, Oguchi, Katsuji, Iino, Masamitsu, Sakurai, Takashi
Published in Human mutation (01.11.2016)
Published in Human mutation (01.11.2016)
Get full text
Journal Article
Dual role of the S5 segment in type 1 ryanodine receptor channel gating
Murayama, Takashi, Otori, Yuya, Kurebayashi, Nagomi, Yamazawa, Toshiko, Oyamada, Hideto, Sakurai, Takashi, Ogawa, Haruo
Published in Communications biology (18.09.2024)
Published in Communications biology (18.09.2024)
Get full text
Journal Article
Primary cultured neuronal networks and type 2 diabetes model mouse fatty liver tissues in aqueous liquid observed by atmospheric SEM (ASEM): Staining preferences of metal solutions
Sato, Chikara, Yamazawa, Toshiko, Ohtani, Akiko, Maruyama, Yuusuke, Memtily, Nassirhadjy, Sato, Mari, Hatano, Yuri, Shiga, Takashi, Ebihara, Tatsuhiko
Published in Micron (Oxford, England : 1993) (01.03.2019)
Published in Micron (Oxford, England : 1993) (01.03.2019)
Get full text
Journal Article
Nitric Oxide-induced Activation of the Type 1 Ryanodine Receptor Is Critical for Epileptic Seizure-induced Neuronal Cell Death
Mikami, Yoshinori, Kanemaru, Kazunori, Okubo, Yohei, Nakaune, Takuya, Suzuki, Junji, Shibata, Kazuki, Sugiyama, Hiroki, Koyama, Ryuta, Murayama, Takashi, Ito, Akihiro, Yamazawa, Toshiko, Ikegaya, Yuji, Sakurai, Takashi, Saito, Nobuhito, Kakizawa, Sho, Iino, Masamitsu
Published in EBioMedicine (01.09.2016)
Published in EBioMedicine (01.09.2016)
Get full text
Journal Article
Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region
Murayama, Takashi, Kurebayashi, Nagomi, Yamazawa, Toshiko, Oyamada, Hideto, Suzuki, Junji, Kanemaru, Kazunori, Oguchi, Katsuji, Iino, Masamitsu, Sakurai, Takashi
Published in PloS one (26.06.2015)
Published in PloS one (26.06.2015)
Get full text
Journal Article
Inositol 1,4,5-trisphosphate signaling maintains the activity of glutamate uptake in Bergmann glia
Mashimo, Masato, Okubo, Yohei, Yamazawa, Toshiko, Yamasaki, Miwako, Watanabe, Masahiko, Murayama, Toshihiko, Iino, Masamitsu
Published in The European journal of neuroscience (01.11.2010)
Published in The European journal of neuroscience (01.11.2010)
Get full text
Journal Article
Nitric oxide-induced calcium release via ryanodine receptors regulates neuronal function
Kakizawa, Sho, Yamazawa, Toshiko, Chen, Yili, Ito, Akihiro, Murayama, Takashi, Oyamada, Hideto, Kurebayashi, Nagomi, Sato, Osamu, Watanabe, Masahiko, Mori, Nozomu, Oguchi, Katsuji, Sakurai, Takashi, Takeshima, Hiroshi, Saito, Nobuhito, Iino, Masamitsu
Published in The EMBO journal (18.01.2012)
Published in The EMBO journal (18.01.2012)
Get full text
Journal Article
Approaches to physical fitness and sports medicine through X-ray diffraction analysis of striated muscle
Yamaguchi, Maki, Takemori, Shigeru, Kimura, Masako, Nakahara, Naoya, Ohno, Tetsuo, Yamazawa, Toshiko, Yokomizo, Shunya, Akiyama, Nobutake, Yagi, Naoto
Published in The Journal of Physical Fitness and Sports Medicine (2016)
Published in The Journal of Physical Fitness and Sports Medicine (2016)
Get full text
Journal Article
P1-5-7 Induction of neuronal cell death through S-nitrosylation of the type 1 ryanodine receptor
Yoshinori Mikami, Kazunori Kanemaru, Yasuhiro Oda, Akihiro Ito, Sho Kakizawa, Toshiko Yamazawa, Nobuhito Saito, Masamitsu Iino
Published in Journal of Pharmacological Sciences (15.02.2014)
Get full text
Published in Journal of Pharmacological Sciences (15.02.2014)
Journal Article