Search Results - "Toshiaki Sakamoto" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of 2-[(E)-2-(7-Fluoro-3-methylquinoxalin-2-yl)vinyl]-6-pyrrolidin-1-yl-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine Hydrochloride as a Highly Selective PDE10A Inhibitor

Discovery of 2-[(E)-2-(7-Fluoro-3-methylquinoxalin-2-yl)vinyl]-6-pyrrolidin-1-yl-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine Hydrochloride as a Highly Selective PDE10A Inhibitor

by Kadoh, Yoichi, Miyoshi, Haruko, Matsumura, Takehiko, Tanaka, Yoshihito, Hongu, Mitsuya, Kimura, Mayumi, Takedomi, Kei, Omori, Kenji, Kotera, Jun, Sasaki, Takashi, Kobayashi, Tamaki, Taniguchi, Hiroyuki, Watanabe, Yumi, Kojima, Koki, Sakamoto, Toshiaki, Himiyama, Toshiyuki, Kawanishi, Eiji
Published in Chemical & pharmaceutical bulletin (2018)

Get full text

Journal Article

Histone deacetylase inhibitors enhance the chemosensitivity of tumor cells with cross‐resistance to a wide range of DNA‐damaging drugs

Histone deacetylase inhibitors enhance the chemosensitivity of tumor cells with cross‐resistance to a wide range of DNA‐damaging drugs

by Ozaki, Kei‐ichi, Kishikawa, Futaba, Tanaka, Masashi, Sakamoto, Toshiaki, Tanimura, Susumu, Kohno, Michiaki
Published in Cancer science (01.02.2008)

Get full text

Journal Article

The discovery of avanafil for the treatment of erectile dysfunction: A novel pyrimidine-5-carboxamide derivative as a potent and highly selective phosphodiesterase 5 inhibitor

The discovery of avanafil for the treatment of erectile dysfunction: A novel pyrimidine-5-carboxamide derivative as a potent and highly selective phosphodiesterase 5 inhibitor

by Sakamoto, Toshiaki, Koga, Yuichi, Hikota, Masataka, Matsuki, Kenji, Murakami, Michino, Kikkawa, Kohei, Fujishige, Kotomi, Kotera, Jun, Omori, Kenji, Morimoto, Hiroshi, Yamada, Koichiro
Published in Bioorganic & medicinal chemistry letters (01.12.2014)

Get full text

Journal Article

Evaluation of Antiemetic Therapy for Hepatic Transcatheter Arterial Infusion Chemotherapy with Cisplatin

Evaluation of Antiemetic Therapy for Hepatic Transcatheter Arterial Infusion Chemotherapy with Cisplatin

by Hashizume, Junya, Higuchi, Norihide, Sato, Kayoko, Kodama, Yukinobu, Matsunaga, Noriko, Sakamoto, Toshiaki, Yamaguchi, Kentaro, Nakamura, Tadahiro, Kitahara, Takashi, Sasaki, Hitoshi
Published in Biological & pharmaceutical bulletin (01.04.2016)

Get full text

Journal Article

Blockade of the ERK or PI3K–Akt signaling pathway enhances the cytotoxicity of histone deacetylase inhibitors in tumor cells resistant to gefitinib or imatinib

Blockade of the ERK or PI3K–Akt signaling pathway enhances the cytotoxicity of histone deacetylase inhibitors in tumor cells resistant to gefitinib or imatinib

by Ozaki, Kei-ichi, Kosugi, Masaki, Baba, Nobuyuki, Fujio, Kohsuke, Sakamoto, Toshiaki, Kimura, Shinya, Tanimura, Susumu, Kohno, Michiaki
Published in Biochemical and biophysical research communications (22.01.2010)

Get full text

Journal Article

Blockade of the ERK pathway enhances the therapeutic efficacy of the histone deacetylase inhibitor MS-275 in human tumor xenograft models

Blockade of the ERK pathway enhances the therapeutic efficacy of the histone deacetylase inhibitor MS-275 in human tumor xenograft models

by Sakamoto, Toshiaki, Ozaki, Kei-ichi, Fujio, Kohsuke, Kajikawa, Shu-hei, Uesato, Shin-ichi, Watanabe, Kazushi, Tanimura, Susumu, Koji, Takehiko, Kohno, Michiaki
Published in Biochemical and biophysical research communications (19.04.2013)

Get full text

Journal Article

Blockade of the Extracellular Signal-Regulated Kinase Pathway Enhances the Therapeutic Efficacy of Microtubule-Destabilizing Agents in Human Tumor Xenograft Models

Blockade of the Extracellular Signal-Regulated Kinase Pathway Enhances the Therapeutic Efficacy of Microtubule-Destabilizing Agents in Human Tumor Xenograft Models

by WATANABE, Kazushi, TANIMURA, Susumu, UCHIYAMA, Aya, SAKAMOTO, Toshiaki, KAWABATA, Takumi, OZAKI, Kei-Ichi, KOHNO, Michiaki
Published in Clinical cancer research (15.02.2010)

Get full text

Journal Article

Evaluation of Antiemetic Therapy for Hepatic Transcatheter Arterial Infusion Chemotherapy with Cisplatin

Evaluation of Antiemetic Therapy for Hepatic Transcatheter Arterial Infusion Chemotherapy with Cisplatin

by Junya Hashizume, Norihide Higuchi, Kayoko Sato, Yukinobu Kodama, Noriko Matsunaga, Toshiaki Sakamoto, Kentaro Yamaguchi, Tadahiro Nakamura, Takashi Kitahara, Hitoshi Sasaki
Published in Biological and Pharmaceutical Bulletin (01.04.2016)

Get full text

Journal Article

Discovery of Canagliflozin, a Novel C-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus

Discovery of Canagliflozin, a Novel C-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus

by Nomura, Sumihiro, Sakamaki, Shigeki, Hongu, Mitsuya, Kawanishi, Eiji, Koga, Yuichi, Sakamoto, Toshiaki, Yamamoto, Yasuo, Ueta, Kiichiro, Kimata, Hirotaka, Nakayama, Keiko, Tsuda-Tsukimoto, Minoru
Published in Journal of medicinal chemistry (09.09.2010)

Get full text

Journal Article

Discovery of Clinical Candidate AZD5462, a Selective Oral Allosteric RXFP1 Agonist for Treatment of Heart Failure

Discovery of Clinical Candidate AZD5462, a Selective Oral Allosteric RXFP1 Agonist for Treatment of Heart Failure

by Granberg, Kenneth L., Sakamaki, Shigeki, Larsson, Niklas, Bergström, Fredrik, Fuchigami, Ryuichi, Niwa, Yasuki, Ryberg, Erik, Backmark, Anna, Kato, Harutoshi, Miyazaki, Shiki, Iguchi, Kaori, Sakamoto, Toshiaki, Persson, Mikael, Idei, Akiko, Prieto Garcia, Luna, Villar, Inmaculada C., Gradén, Henrik, Bergonzini, Giulia, Arvidsson, Torbjörn, Fujita, Takuya, Althage, Magnus, Ulander, Johan, Kimura, Junpei, Yoneda, Hikaru, Fjellström, Ola, Mochida, Hideki, Lal, Mark
Published in Journal of medicinal chemistry (28.03.2024)

Get full text

Journal Article

C-Glucosides with heteroaryl thiophene as novel sodium-dependent Cross Mark glucose cotransporter 2 inhibitors

C-Glucosides with heteroaryl thiophene as novel sodium-dependent Cross Mark glucose cotransporter 2 inhibitors

by Koga, Yuichi, Sakamaki, Shigeki, Hongu, Mitsuya, Kawanishi, Eiji, Sakamoto, Toshiaki, Yamamoto, Yasuo, Kimata, Hirotaka, Nakayama, Keiko, Kuriyama, Chiaki, Matsushita, Yasuaki, Ueta, Kiichiro, Tsuda-Tsukimoto, Minoru, Nomura, Sumihiro
Published in Bioorganic & medicinal chemistry (01.09.2013)

Get full text

Journal Article

Design and synthesis of novel 5-(3,4,5-trimethoxybenzoyl)-4-aminopyrimidine derivatives as potent and selective phosphodiesterase 5 inhibitors: Scaffold hopping using a pseudo-ring by intramolecular hydrogen bond formation

Design and synthesis of novel 5-(3,4,5-trimethoxybenzoyl)-4-aminopyrimidine derivatives as potent and selective phosphodiesterase 5 inhibitors: Scaffold hopping using a pseudo-ring by intramolecular hydrogen bond formation

by Sakamoto, Toshiaki, Koga, Yuichi, Hikota, Masataka, Matsuki, Kenji, Murakami, Michino, Kikkawa, Kohei, Fujishige, Kotomi, Kotera, Jun, Omori, Kenji, Morimoto, Hiroshi, Yamada, Koichiro
Published in Bioorganic & medicinal chemistry letters (15.11.2014)

Get full text

Journal Article

8-(3-Chloro-4-methoxybenzyl)-8H-pyrido[2,3-d]pyrimidin-7-one derivatives as potent and selective phosphodiesterase 5 inhibitors

8-(3-Chloro-4-methoxybenzyl)-8H-pyrido[2,3-d]pyrimidin-7-one derivatives as potent and selective phosphodiesterase 5 inhibitors

by Sakamoto, Toshiaki, Koga, Yuichi, Hikota, Masataka, Matsuki, Kenji, Mochida, Hideki, Kikkawa, Kohei, Fujishige, Kotomi, Kotera, Jun, Omori, Kenji, Morimoto, Hiroshi, Yamada, Koichiro
Published in Bioorganic & medicinal chemistry letters (01.04.2015)

Get full text

Journal Article

N-glucosides as human sodium-dependent glucose cotransporter 2 (hSGLT2) inhibitors

N-glucosides as human sodium-dependent glucose cotransporter 2 (hSGLT2) inhibitors

by Yamamoto, Yasuo, Kawanishi, Eiji, Koga, Yuichi, Sakamaki, Shigeki, Sakamoto, Toshiaki, Ueta, Kiichiro, Matsushita, Yasuaki, Kuriyama, Chiaki, Tsuda-Tsukimoto, Minoru, Nomura, Sumihiro
Published in Bioorganic & medicinal chemistry letters (15.10.2013)

Get full text

Journal Article

C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors

C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors

by Koga, Yuichi, Sakamaki, Shigeki, Hongu, Mitsuya, Kawanishi, Eiji, Sakamoto, Toshiaki, Yamamoto, Yasuo, Kimata, Hirotaka, Nakayama, Keiko, Kuriyama, Chiaki, Matsushita, Yasuaki, Ueta, Kiichiro, Tsuda-Tsukimoto, Minoru, Nomura, Sumihiro
Published in Bioorganic & medicinal chemistry (01.09.2013)

Get full text

Journal Article

5,10,15,20-TETRAKIS(2-AMINO-6-METHOXYCARBONYLPHENYL)PORPHYRIN - SYNTHESIS AND SEPARATION OF ATROPISOMERS USEFUL FOR PORPHYRIN ARCHITECTURE

5,10,15,20-TETRAKIS(2-AMINO-6-METHOXYCARBONYLPHENYL)PORPHYRIN - SYNTHESIS AND SEPARATION OF ATROPISOMERS USEFUL FOR PORPHYRIN ARCHITECTURE

by NISHINO, N, SAKAMOTO, T, KIYOTA, H, MIHARA, H, YANAI, T, FUJIMOTO, T
Published in Chemistry letters (01.02.1993)

Get more information

Journal Article

Cationic electrodeposition coating composition and coated article therewith

Cationic electrodeposition coating composition and coated article therewith

by SAKAMOTO TOSHIAKI,SAKAMOTO MASARU,HIRAHARA YOSHINORI,SHIGENAGA TSUTOMU
Year of Publication 07.02.2007

Get full text

Patent

Piperidineacrylate Derivatives as Potential Antiallergy Agents

Piperidineacrylate Derivatives as Potential Antiallergy Agents

by SUGIYAMA, Mitsuo, SAKAMOTO, Toshiaki, KAMIGAKI, Yumiko, FUKUMI, Hiroshi, ITOH, Kazuhiro, SATOH, Yumiko, YAMAGUCHI, Takeshi
Published in Chemical & pharmaceutical bulletin (1993)

Get full text

Journal Article

A Novel Heterocyclic Compound. Synthesis and Reactivities of an Oxazolo[3, 2-a]thieno[3, 2-d]pyrimidine Derivative

A Novel Heterocyclic Compound. Synthesis and Reactivities of an Oxazolo[3, 2-a]thieno[3, 2-d]pyrimidine Derivative

by FUKUMI, Hiroshi, SUGIYAMA, Mitsuo, SAKAMOTO, Toshiaki
Published in Chemical & pharmaceutical bulletin (1989)

Get full text

Journal Article

Network camera

Network camera

by Sakamoto, Toshiaki, Hasegawa, Takashi
Year of Publication 14.01.2020

Get full text

Patent

1
2
3
4
5
6
7
8
9
10
11
Next
[20]