Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition
Sadaie, Mahito, Dillon, Christian, Narita, Masako, Narita, Masashi, Young, Andrew R J, Cairney, Claire J, Godwin, Lauren S, Torrance, Christopher J, Bennett, Dorothy C, Keith, W Nicol, Narita, Masashi
Published in Molecular biology of the cell (01.09.2015)
Published in Molecular biology of the cell (01.09.2015)
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Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS
Narvaez, Ana J., Ber, Suzan, Crooks, Alex, Emery, Amy, Hardwick, Bryn, Guarino Almeida, Estrella, Huggins, David J., Perera, David, Roberts-Thomson, Meredith, Azzarelli, Roberta, Hood, Fiona E., Prior, Ian A., Walker, David W., Boyce, Richard, Boyle, Robert G., Barker, Samuel P., Torrance, Christopher J., McKenzie, Grahame J., Venkitaraman, Ashok R.
Published in Cell chemical biology (17.08.2017)
Published in Cell chemical biology (17.08.2017)
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A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds
Cairney, Claire J, Godwin, Lauren S, Bilsland, Alan E, Burns, Sharon, Stevenson, Katrina H, McGarry, Lynn, Revie, John, Moore, Jon D, Wiggins, Ceri M, Collinson, Rebecca S, Mudd, Clare, Tsonou, Elpida, Sadaie, Mahito, Bennett, Dorothy C, Narita, Masashi, Torrance, Christopher J, Keith, W Nicol
Published in PLoS genetics (01.08.2017)
Published in PLoS genetics (01.08.2017)
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Combinatorial chemoprevention of intestinal neoplasia
Frost, Philip, Torrance, Christopher J, Jackson, Peta E, Montgomery, Elizabeth, Kinzler, Kenneth W, Vogelstein, Bert, Wissner, Allan, Nunes, Maria, Discafani, Carolyn M
Published in Nature medicine (01.09.2000)
Published in Nature medicine (01.09.2000)
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Use of isogenic human cancer cells for high-throughput screening and drug discovery
Vogelstein, Bert, Torrance, Christopher J, Agrawal, Vijai, Kinzler, Kenneth W
Published in Nature biotechnology (01.10.2001)
Published in Nature biotechnology (01.10.2001)
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Journal Article
DEC1 is a Downstream Target of TGF-β with Sequence-Specific Transcriptional Repressor Activities
Zawel, Leigh, Yu, Jian, Torrance, Christopher J., Markowitz, Sanford, Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2002)
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Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library
Emery, Amy, Hardwick, Bryn S., Crooks, Alex T., Milech, Nadia, Watt, Paul M., Mithra, Chandan, Kumar, Vikrant, Giridharan, Saranya, Sadasivam, Gayathri, Mathivanan, Subashini, Sudhakar, Sneha, Bairy, Sneha, Bharatham, Kavitha, Hurakadli, Manjunath A., Prasad, Thazhe K., Kamariah, Neelagandan, Muellner, Markus, Coelho, Miguel, Torrance, Christopher J., McKenzie, Grahame J., Venkitaraman, Ashok R.
Published in Cell chemical biology (18.11.2021)
Published in Cell chemical biology (18.11.2021)
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Cancer cell senescence: a new frontier in drug development
Cairney, Claire J., Bilsland, Alan E., Evans, T.R. Jeffry, Roffey, Jon, Bennett, Dorothy C., Narita, Masashi, Torrance, Christopher J., Keith, W. Nicol
Published in Drug discovery today (01.03.2012)
Published in Drug discovery today (01.03.2012)
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Effects of Thyroid Hormone on GLUT4 Glucose Transporter Gene Expression and NIDDM in Rats
Torrance, Christopher J, deVente, James E, Jones, Jared P, Dohm, G. Lynis
Published in Endocrinology (Philadelphia) (01.03.1997)
Published in Endocrinology (Philadelphia) (01.03.1997)
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Triazolo[1,5- a]pyrimidines as novel CDK2 inhibitors: Protein structure-guided design and SAR
Richardson, Christine M., Williamson, Douglas S., Parratt, Martin J., Borgognoni, Jenifer, Cansfield, Andrew D., Dokurno, Pawel, Francis, Geraint L., Howes, Rob, Moore, Jonathan D., Murray, James B., Robertson, Alan, Surgenor, Allan E., Torrance, Christopher J.
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scoping
Richardson, Christine M., Nunns, Claire L., Williamson, Douglas S., Parratt, Martin J., Dokurno, Pawel, Howes, Rob, Borgognoni, Jenifer, Drysdale, Martin J., Finch, Harry, Hubbard, Roderick E., Jackson, Philip S., Kierstan, Peter, Lentzen, Georg, Moore, Jonathan D., Murray, James B., Simmonite, Heather, Surgenor, Allan E., Torrance, Christopher J.
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
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Structure-guided design of pyrazolo[1,5- a]pyrimidines as inhibitors of human cyclin-dependent kinase 2
Williamson, Douglas S., Parratt, Martin J., Bower, Justin F., Moore, Jonathan D., Richardson, Christine M., Dokurno, Pawel, Cansfield, Andrew D., Francis, Geraint L., Hebdon, Richard J., Howes, Rob, Jackson, Philip S., Lockie, Andrea M., Murray, James B., Nunns, Claire L., Powles, Jenifer, Robertson, Alan, Surgenor, Allan E., Torrance, Christopher J.
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
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