Phosphodiesterases: the journey towards therapeutics
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Journal Article
Conference Proceeding
Considerations for the Conduct of Clinical Trials with Antiinflammatory Agents in Cystic Fibrosis. A Cystic Fibrosis Foundation Workshop Report
Torphy, Theodore J, Allen, Janet, Cantin, André M, Konstan, Michael W, Accurso, Frank J, Joseloff, Elizabeth, Ratjen, Felix A, Chmiel, James F
Published in Annals of the American Thoracic Society (01.09.2015)
Published in Annals of the American Thoracic Society (01.09.2015)
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Journal Article
Suppression of human inflammatory cell function by subtype‐selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B
Manning, Carol D, Burman, Miriam, Christensen, Siegfried B, Cieslinski, Lenora B, Essayan, David M, Grous, Marilyn, Torphy, Theodore J, Barnette, Mary S
Published in British journal of pharmacology (01.12.1999)
Published in British journal of pharmacology (01.12.1999)
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Journal Article
Tumor Necrosis Factor-alpha -Induced Secretion of RANTES and Interleukin-6 from Human Airway Smooth-Muscle Cells . Modulation by Cyclic Adenosine Monophosphate
Ammit, Alaina J, Hoffman, Rebecca K, Amrani, Yassine, Lazaar, Aili L, Hay, Douglas W. P, Torphy, Theodore J, Penn, Raymond B, Panettieri, Reynold A., Jr
Published in American journal of respiratory cell and molecular biology (01.12.2000)
Published in American journal of respiratory cell and molecular biology (01.12.2000)
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Journal Article
Crystal structure, absolute configuration, and phosphodiesterase inhibitory activity of (+)-1-(4-bromobenzyl)-4-[(3-cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
Baures, Paul W, Eggleston, Drake S, Erhard, Karl F, Cieslinski, Lenora B, Torphy, Theodore J, Christensen, Siegfried B
Published in Journal of medicinal chemistry (01.10.1993)
Published in Journal of medicinal chemistry (01.10.1993)
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Journal Article
Monoclonal antibodies as a strategy for pulmonary diseases
Torphy, Theodore J, Li, Li, Griswold, Don E
Published in Current Opinion in Pharmacology (01.06.2001)
Published in Current Opinion in Pharmacology (01.06.2001)
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Book Review
Journal Article
What's in the Pipeline? Prospects for Monoclonal Antibodies (mAbs) as Therapies for Lung Diseases
Li, Li, Das, Anuk M, Torphy, Theodore J, Griswold, Don E
Published in Pulmonary pharmacology & therapeutics (01.01.2002)
Published in Pulmonary pharmacology & therapeutics (01.01.2002)
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Journal Article
Identification, Characterization, and Functional Role of Phosphodiesterase Type IV in Cerebral Vessels: Effects of Selective Phosphodiesterase Inhibitors
Willette, Robert N., Shiloh, Aaron O., Sauermelch, Charles F., Sulpizio, Anthony, Michell, Marcus P., Cieslinski, Lenora B., Torphy, Theodore J., Ohlstein, E. H.
Published in Journal of cerebral blood flow and metabolism (01.02.1997)
Published in Journal of cerebral blood flow and metabolism (01.02.1997)
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Journal Article
Coming of age: anti-cytokine therapies
Song, Xiao-yu R, Torphy, Theodore J, Griswold, Don E, Shealy, David
Published in Molecular interventions (01.02.2002)
Published in Molecular interventions (01.02.2002)
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Journal Article
The Influence of Endogenous Catecholamines on the Inhibitory Effects of Rolipram Against Early- and Late-Phase Response to Antigen in the Guinea Pig
Underwood, D C, Matthews, J K, Osborn, R R, Bochnowicz, S, Torphy, T J
Published in The Journal of pharmacology and experimental therapeutics (01.01.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.01.1997)
Journal Article
Inhibitors of CoA-independent transacylase block the movement of arachidonate into 1-ether-linked phospholipids of human neutrophils
Chilton, Floyd H, Fonteh, Alfred N, Sung, Chiu-Mei, Hickey, Deirdre M. B, Torphy, Theodore J, Mayer, Ruth J, Marshall, Lisa A, Heravi, Javid D, Winkler, James D
Published in Biochemistry (Easton) (25.04.1995)
Published in Biochemistry (Easton) (25.04.1995)
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Journal Article
β-Adrenoceptors, cAMP and airway smooth muscle relaxation: challenges to the dogma
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Book Review
Journal Article
Cysteinyl leukotrienes in asthma: old mediators up to new tricks
Hay, Douglas W.P., Torphy, Theodore J., Undem, Bradley J.
Published in Trends in Pharmacological Sciences (01.09.1995)
Published in Trends in Pharmacological Sciences (01.09.1995)
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Book Review
Journal Article
SB 207499 (Ariflo), a potent and selective second-generation phosphodiesterase 4 inhibitor: in vitro anti-inflammatory actions
Barnette, M S, Christensen, S B, Essayan, D M, Grous, M, Prabhakar, U, Rush, J A, Kagey-Sobotka, A, Torphy, T J
Published in The Journal of pharmacology and experimental therapeutics (01.01.1998)
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Published in The Journal of pharmacology and experimental therapeutics (01.01.1998)
Journal Article
SB 207499 (Ariflo), a second generation phosphodiesterase 4 inhibitor, reduces tumor necrosis factor alpha and interleukin-4 production in vivo
Griswold, D E, Webb, E F, Badger, A M, Gorycki, P D, Levandoski, P A, Barnette, M A, Grous, M, Christensen, S, Torphy, T J
Published in The Journal of pharmacology and experimental therapeutics (01.11.1998)
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Published in The Journal of pharmacology and experimental therapeutics (01.11.1998)
Journal Article