A low-Km, rolipram-sensitive, cAMP-specific phosphodiesterase from human brain. Cloning and expression of cDNA, biochemical characterization of recombinant protein, and tissue distribution of mRNA
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Published in The Journal of biological chemistry (25.03.1993)
Published in The Journal of biological chemistry (25.03.1993)
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ArifloTM(SB 207499), a Second Generation Phosphodiesterase 4 Inhibitor for the Treatment of Asthma and COPD: from Concept to Clinic
Torphy, T.J., Barnette, M.S., Underwood, D.C., Griswold, D.E., Christensen, S.B., Murdoch, R.D., Nieman, R.B., Compton, C.H.
Published in Pulmonary pharmacology & therapeutics (01.04.1999)
Published in Pulmonary pharmacology & therapeutics (01.04.1999)
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Cloning and expression of cDNA for a human low-K sub m , rolipram-sensitive cyclic AMP phosphodiesterase
Livi, G.P., McHale, M.J., Sathe, G.M., Taylor, D.P., Kmetz, P., Balcarek, J.M., Cieslinski, L.B., Torphy, T.J., Davis, R.L.
Published in Molecular and cellular biology (01.06.1990)
Published in Molecular and cellular biology (01.06.1990)
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Characterization of two human cAMP-specific phosphodiesterase subtypes expressed in baculovirus-infected insect cells
Amegadzie, B.Y, Hanning, C.R, McLaughlin, M.M, Burman, M, Cieslinski, L.B, Livi, G.P, Torphy, T.J. (Department of Gene Expression Sciences, SmithKline Beecham Pharmaceuticals, UE0548, P.O. Box 1539, King of Prussia, PA 19406 (USA))
Published in Cell Biology International (United Kingdom) (1995)
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Published in Cell Biology International (United Kingdom) (1995)
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Pharmacologic and pharmacokinetic profile of SK&F S-106203, a potent, orally active peptidoleukotriene receptor antagonist, in guinea-pig
Hay, D.W.P., Muccitelli, R.M., Vickery-Clark, L.M., Novak, L.S., Osborn, R.R., Gleason, J.G., Yodis, L.-A.P., Saverino, C.M., Eckardt, R.D., Sarau, H.M., Wasserman, M.A., Torphy, T.J., Newton, J.F.
Published in Pulmonary pharmacology (Edinburgh) (1991)
Published in Pulmonary pharmacology (Edinburgh) (1991)
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