Clinical-grade generation of active NK cells from cord blood hematopoietic progenitor cells for immunotherapy using a closed-system culture process
Spanholtz, Jan, Preijers, Frank, Tordoir, Marleen, Trilsbeek, Carel, Paardekooper, Jos, de Witte, Theo, Schaap, Nicolaas, Dolstra, Harry
Published in PloS one (16.06.2011)
Published in PloS one (16.06.2011)
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Successful Transfer of Umbilical Cord Blood CD34 + Hematopoietic Stem and Progenitor-derived NK Cells in Older Acute Myeloid Leukemia Patients
Dolstra, Harry, Roeven, Mieke W H, Spanholtz, Jan, Hangalapura, Basav N, Tordoir, Marleen, Maas, Frans, Leenders, Marij, Bohme, Fenna, Kok, Nina, Trilsbeek, Carel, Paardekooper, Jos, van der Waart, Anniek B, Westerweel, Peter E, Snijders, Tjeerd J F, Cornelissen, Jan, Bos, Gerard, Pruijt, Hans F M, de Graaf, Aniek O, van der Reijden, Bert A, Jansen, Joop H, van der Meer, Arnold, Huls, Gerwin, Cany, Jeannette, Preijers, Frank, Blijlevens, Nicole M A, Schaap, Nicolaas M
Published in Clinical cancer research (01.08.2017)
Published in Clinical cancer research (01.08.2017)
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Combination of NK Cells and Cetuximab to Enhance Anti-Tumor Responses in RAS Mutant Metastatic Colorectal Cancer
Veluchamy, John Pradeep, Spanholtz, Jan, Tordoir, Marleen, Thijssen, Victor L, Heideman, Daniëlle A M, Verheul, Henk M W, de Gruijl, Tanja D, van der Vliet, Hans J
Published in PloS one (17.06.2016)
Published in PloS one (17.06.2016)
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Journal Article
High log-scale expansion of functional human natural killer cells from umbilical cord blood CD34-positive cells for adoptive cancer immunotherapy
Spanholtz, Jan, Tordoir, Marleen, Eissens, Diana, Preijers, Frank, van der Meer, Arnold, Joosten, Irma, Schaap, Nicolaas, de Witte, Theo M, Dolstra, Harry
Published in PloS one (15.02.2010)
Published in PloS one (15.02.2010)
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Natural Killer Cells Generated from Cord Blood Hematopoietic Progenitor Cells Efficiently Target Bone Marrow-Residing Human Leukemia Cells in NOD/SCID/IL2Rgnull Mice
Cany, Jeannette, van der Waart, Anniek B., Tordoir, Marleen, Franssen, Gerben M., Hangalapura, Basav N., de Vries, Jolanda, Boerman, Otto, Schaap, Nicolaas, van der Voort, Robbert, Spanholtz, Jan, Dolstra, Harry
Published in PloS one (05.06.2013)
Published in PloS one (05.06.2013)
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Natural killer cells generated from cord blood hematopoietic progenitor cells efficiently target bone marrow-residing human leukemia cells in NOD/SCID/IL2Rg(null) mice
Cany, Jeannette, van der Waart, Anniek B, Tordoir, Marleen, Franssen, Gerben M, Hangalapura, Basav N, de Vries, Jolanda, Boerman, Otto, Schaap, Nicolaas, van der Voort, Robbert, Spanholtz, Jan, Dolstra, Harry
Published in PloS one (2013)
Published in PloS one (2013)
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Combined IL-15 and IL-12 drives the generation of CD34+-derived natural killer cells with superior maturation and alloreactivity potential following adoptive transfer
Cany, Jeannette, van der Waart, Anniek B, Spanholtz, Jan, Tordoir, Marleen, Jansen, Joop H, van der Voort, Robbert, Schaap, Nicolaas M, Dolstra, Harry
Published in Oncoimmunology (03.07.2015)
Published in Oncoimmunology (03.07.2015)
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Journal Article
Ex vivo generated natural killer cells acquire typical natural killer receptors and display a cytotoxic gene expression profile similar to peripheral blood natural killer cells
Lehmann, Dorit, Spanholtz, Jan, Osl, Markus, Tordoir, Marleen, Lipnik, Karoline, Bilban, Martin, Schlechta, Bernhard, Dolstra, Harry, Hofer, Erhard
Published in Stem cells and development (01.11.2012)
Published in Stem cells and development (01.11.2012)
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Influence Of DNA Methyltransferese Inhibitors On The Anti-Leukemic Effect Of Umbilical Cord Blood Derived NK Cells Against Acute Myeloid Leukemia
Dolstra, Harry, Cany, Jeannette, van der Waart, Anniek B., Tordoir, Marleen, Hangalapura, Basav Nagaraj, Spanholtz, Jan, van der Voort, Robbert, Schaap, Nicolaas PM
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
A Phase I Study of Allogeneic Natural Killer Cell Therapy Generated from Cord Blood Hematopoietic Stem and Progenitor Cells in Elderly Acute Myeloid Leukemia Patients
Dolstra, Harry, Roeven, Mieke W.H., Spanholtz, Jan, Hangalapura, Basav, Tordoir, Marleen, Maas, Frans, Leenders, Marij, Bohme, Fenna, Kok, Nina, Trilsbeek, Carel, Paardekooper, Jos, Van der Waart, Anniek B., Westerweel, Peter, Snijders, Tjeerd J.F., Bos, Gerard M.J., Cornelissen, Jan J., Pruijt, Hans, Huls, Gerwin, de Graaf, Aniek, van der Reijden, Bert A., Blijlevens, Nicole M.A., Jansen, Joop H., van der Meer, Arnold, Cany, Jeannette, Preijers, Frank, Schaap, Nicolaas P.M.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Natural Killer Cells Generated from Cord Blood Hematopoietic Progenitor Cells Efficiently Target Bone Marrow-Residing Human Leukemia Cells in NOD/SCID/IL2Rg.sup.null Mice
Cany, Jeannette, van der Waart, Anniek B, Tordoir, Marleen, Franssen, Gerben M, Hangalapura, Basav N, de Vries, Jolanda, Boerman, Otto, Schaap, Nicolaas, van der Voort, Robbert, Spanholtz, Jan, Dolstra, Harry
Published in PloS one (05.06.2013)
Published in PloS one (05.06.2013)
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Journal Article
Clinical Scale Generation of Functional Human Natural Killer Cells From Umbilical Cord Blood CD34-Positive Cells for Immunotherapy
Spanholtz, Jan, Tordoir, Marleen, Trilsbeek, Carel, Paardekooper, Jos, Eissens, Diana, van der Meer, Arnold, Joosten, Irma, Preijers, Frank, de Witte, T.M., Schaap, Nicolaas, Dolstra, Harry
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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Natural Killer Cells Generated from Cord Blood Hematopoietic Progenitor Cells Efficiently Target Bone Marrow-Residing Human Leukemia Cells in NOD/SCID/IL2Rgnull Mice. e64384
Cany, Jeannette, Waart, B vander, Tordoir, Marleen, Franssen, Gerben M, Hangalapura, Basav N, Vries, Jolanda de, Boerman, Otto, Schaap, Nicolaas, Voort, Robbert vander, Spanholtz, Jan
Published in PloS one (01.06.2013)
Published in PloS one (01.06.2013)
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