Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections
Brickner, Steven J, Hutchinson, Douglas K, Barbachyn, Michael R, Manninen, Peter R, Ulanowicz, Debra A, Garmon, Stuart A, Grega, Kevin C, Hendges, Susan K, Toops, Dana S, Ford, Charles W, Zurenko, Gary E
Published in Journal of medicinal chemistry (02.02.1996)
Published in Journal of medicinal chemistry (02.02.1996)
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Journal Article
Identification of a Novel Oxazolidinone (U-100480) with Potent Antimycobacterial Activity
Barbachyn, Michael R, Hutchinson, Douglas K, Brickner, Steven J, Cynamon, Michael H, Kilburn, James O, Klemens, Sally P, Glickman, Suzanne E, Grega, Kevin C, Hendges, Susan K, Toops, Dana S, Ford, Charles W, Zurenko, Gary E
Published in Journal of medicinal chemistry (02.02.1996)
Published in Journal of medicinal chemistry (02.02.1996)
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Journal Article
Design, synthesis, and evaluation of novel oxazolidinone antibacterial agents active against multidrug-resistant bacteria
Barbachyn, M R, Brickner, S J, Gadwood, R C, Garmon, S A, Grega, K C, Hutchinson, D K, Munesada, K, Reischer, R J, Taniguchi, M, Thomasco, L M, Toops, D S, Yamada, H, Ford, C W, Zurenko, G E
Published in Advances in experimental medicine and biology (1998)
Published in Advances in experimental medicine and biology (1998)
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Identification of Phenylisoxazolines as Novel and Viable Antibacterial Agents Active against Gram-Positive Pathogens
Barbachyn, Michael R, Cleek, Gary J, Dolak, Lester A, Garmon, Stuart A, Morris, Joel, Seest, Eric P, Thomas, Richard C, Toops, Dana S, Watt, William, Wishka, Donn G, Ford, Charles W, Zurenko, Gary E, Hamel, Judith C, Schaadt, Ronda D, Stapert, Douglas, Yagi, Betty H, Adams, Wade J, Friis, Janice M, Slatter, J. Gregory, Sams, James P, Oien, Nancee L, Zaya, Matthew J, Wienkers, Larry C, Wynalda, Michael A
Published in Journal of medicinal chemistry (16.01.2003)
Published in Journal of medicinal chemistry (16.01.2003)
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Synthesis and antibacterial activity of new tropone-substituted phenyloxazolidinone antibacterial agents 2. Modification of the phenyl ring — the potentiating effect of fluorine substitution on in vivo activity
Barbachyn, Michael R., Toops, Dana S., Grega, Kevin C., Hendges, Susan K., Ford, Charles W., Zurenko, Gary E., Hamel, Judith C., Schaadt, Jonda D., Stapert, Douglas, Yagi, Betty H., Buysse, Jerry M., Demyan, William F., Kilburn, James O., Glickman, Suzanne E.
Published in Bioorganic & medicinal chemistry letters (07.05.1996)
Published in Bioorganic & medicinal chemistry letters (07.05.1996)
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Journal Article
Synthesis and antibacterial activity of new tropone-substituted phenyloxazolidinone antibacterial agents 1. Identification of leads and importance of the tropone substitution pattern
Barbachyn, Michael R., Toops, Dana S., Ulanowicz, Debra A., Grega, Kevin C., Brickner, Steven J., Ford, Charles W., Zurenko, Gary E., Hamel, Judith C., Schaadt, Ronda D., Stapert, Douglas, Yagi, Betty H., Buysse, Jerry M., Demyan, William F., Kilburn, James O., Glickman, Suzanne E.
Published in Bioorganic & medicinal chemistry letters (07.05.1996)
Published in Bioorganic & medicinal chemistry letters (07.05.1996)
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Journal Article