Report of the First International Symposium on NUT Carcinoma
French, Christopher A, Cheng, Michael L, Hanna, Glenn J, DuBois, Steven G, Chau, Nicole G, Hann, Christine L, Storck, Simone, Salgia, Ravi, Trucco, Matteo, Tseng, Jennifer, Stathis, Anastasios, Piekarz, Richard, Lauer, Ulrich M, Massard, Christophe, Bennett, Kelly, Coker, Shodeinde, Tontsch-Grunt, Ulrike, Sos, Martin L, Liao, Sida, Wu, Catherine J, Polyak, Kornelia, Piha-Paul, Sarina A, Shapiro, Geoffrey I
Published in Clinical cancer research (13.06.2022)
Published in Clinical cancer research (13.06.2022)
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Transcriptional plasticity promotes primary and acquired resistance to BET inhibition
Rathert, Philipp, Roth, Mareike, Neumann, Tobias, Muerdter, Felix, Roe, Jae-Seok, Muhar, Matthias, Deswal, Sumit, Cerny-Reiterer, Sabine, Peter, Barbara, Jude, Julian, Hoffmann, Thomas, Boryń, Łukasz M, Axelsson, Elin, Schweifer, Norbert, Tontsch-Grunt, Ulrike, Dow, Lukas E, Gianni, Davide, Pearson, Mark, Valent, Peter, Stark, Alexander, Kraut, Norbert, Vakoc, Christopher R, Zuber, Johannes
Published in Nature (London) (24.09.2015)
Published in Nature (London) (24.09.2015)
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Triple Angiokinase Inhibitor Nintedanib Directly Inhibits Tumor Cell Growth and Induces Tumor Shrinkage via Blocking Oncogenic Receptor Tyrosine Kinases
Hilberg, Frank, Tontsch-Grunt, Ulrike, Baum, Anke, Le, Anh T, Doebele, Robert C, Lieb, Simone, Gianni, Davide, Voss, Tilman, Garin-Chesa, Pilar, Haslinger, Christian, Kraut, Norbert
Published in The Journal of pharmacology and experimental therapeutics (01.03.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2018)
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Design, Synthesis, and Evaluation of Indolinones as Triple Angiokinase Inhibitors and the Discovery of a Highly Specific 6-Methoxycarbonyl-Substituted Indolinone (BIBF 1120)
Roth, Gerald J, Heckel, Armin, Colbatzky, Florian, Handschuh, Sandra, Kley, Jörg, Lehmann-Lintz, Thorsten, Lotz, Ralf, Tontsch-Grunt, Ulrike, Walter, Rainer, Hilberg, Frank
Published in Journal of medicinal chemistry (23.07.2009)
Published in Journal of medicinal chemistry (23.07.2009)
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Molecular basis of GDF15 induction and suppression by drugs in cardiomyocytes and cancer cells toward precision medicine
Winter, Lisa-Maria, Reinhardt, Diana, Schatter, Ariane, Tissen, Vivien, Wiora, Heike, Gerlach, Daniel, Tontsch-Grunt, Ulrike, Colbatzky, Florian, Stierstorfer, Birgit, Yun, Seong-Wook
Published in Scientific reports (26.07.2023)
Published in Scientific reports (26.07.2023)
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Efficacy and mechanism of action of volasertib, a potent and selective inhibitor of Polo-like kinases, in preclinical models of acute myeloid leukemia
Rudolph, Dorothea, Impagnatiello, Maria Antonietta, Blaukopf, Claudia, Sommer, Christoph, Gerlich, Daniel W, Roth, Mareike, Tontsch-Grunt, Ulrike, Wernitznig, Andreas, Savarese, Fabio, Hofmann, Marco H, Albrecht, Christoph, Geiselmann, Lena, Reschke, Markus, Garin-Chesa, Pilar, Zuber, Johannes, Moll, Jürgen, Adolf, Günther R, Kraut, Norbert
Published in The Journal of pharmacology and experimental therapeutics (01.03.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2015)
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N-myc oncogene overexpression down-regulates IL-6; evidence that IL-6 inhibits angiogenesis and suppresses neuroblastoma tumor growth
HATZI, Elissavet, MURPHY, Carol, ZICHE, Marina, ROFSTAD, Einar K, SCHWEIGERER, Lothar, FOTSIS, Theodore, ZOEPHEL, Andreas, RASMUSSEN, Heidi, MORBIDELLI, Lucia, AHORN, Horst, KUNISADA, Keita, TONTSCH, Ulrike, KLENK, Michael, YAMAUCHI-TAKIHARA, Keiko
Published in Oncogene (16.05.2002)
Published in Oncogene (16.05.2002)
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Transplantation of an Oligodendrocyte Cell Line Leading to Extensive Myelination
Tontsch, U, Archer, D R, Dubois-Dalcq, M, Duncan, I D
Published in Proceedings of the National Academy of Sciences - PNAS (22.11.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (22.11.1994)
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N‐myc oncogene overexpression down‐regulates leukemia inhibitory factor in neuroblastoma
Hatzi, Elissavet, Murphy, Carol, Zoephel, Andreas, Ahorn, Horst, Tontsch, Ulrike, Bamberger, Ana‐Maria, Yamauchi‐Takihara, Keiko, Schweigerer, Lothar, Fotsis, Theodore
Published in European journal of biochemistry (01.08.2002)
Published in European journal of biochemistry (01.08.2002)
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Therapeutic impact of BET inhibitor BI 894999 treatment: backtranslation from the clinic
Tontsch-Grunt, Ulrike, Traexler, Paula-Elena, Baum, Anke, Musa, Hanny, Marzin, Kristell, Wang, Shaonan, Trapani, Francesca, Engelhardt, Harald, Solca, Flavio
Published in British journal of cancer (01.08.2022)
Published in British journal of cancer (01.08.2022)
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The novel BET bromodomain inhibitor BI 894999 represses super-enhancer-associated transcription and synergizes with CDK9 inhibition in AML
Gerlach, Daniel, Tontsch-Grunt, Ulrike, Baum, Anke, Popow, Johannes, Scharn, Dirk, Hofmann, Marco H, Engelhardt, Harald, Kaya, Onur, Beck, Janina, Schweifer, Norbert, Gerstberger, Thomas, Zuber, Johannes, Savarese, Fabio, Kraut, Norbert
Published in Oncogene (01.05.2018)
Published in Oncogene (01.05.2018)
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BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy
Hilberg, Frank, Roth, Gerald J, Krssak, Martin, Kautschitsch, Susanna, Sommergruber, Wolfgang, Tontsch-Grunt, Ulrike, Garin-Chesa, Pilar, Bader, Gerd, Zoephel, Andreas, Quant, Jens, Heckel, Armin, Rettig, Wolfgang J
Published in Cancer research (Chicago, Ill.) (15.06.2008)
Published in Cancer research (Chicago, Ill.) (15.06.2008)
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Synergistic activity of BET inhibitor BI 894999 with PLK inhibitor volasertib in AML in vitro and in vivo
Tontsch-Grunt, Ulrike, Rudolph, Dorothea, Waizenegger, Irene, Baum, Anke, Gerlach, Daniel, Engelhardt, Harald, Wurm, Melanie, Savarese, Fabio, Schweifer, Norbert, Kraut, Norbert
Published in Cancer letters (01.05.2018)
Published in Cancer letters (01.05.2018)
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Abstract 5194: Epigenomic and transcriptional profiling of CRC cell lines with distinct response patterns to the BET inhibitor BI 894999
Savarese, Fabio, Gerlach, Daniel, Koller, Larissa, Straubinger, Susy, Träxler, Paula Elena, Kaya, Onur, Schweifer, Norbert, Tontsch-Grunt, Ulrike, Kraut, Norbert
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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An orally-available monovalent SMAC mimetic compound as a broad-spectrum antiviral
Mei, Miao, Impagnatiello, Maria Antonietta, Jiao, Jun, Reiser, Ulrich, Tontsch-Grunt, Ulrike, Zhang, Ju, Nicklin, Paul, Yu, Bingke, Wang, Yu, He, Yuan, Tan, Xu
Published in Protein & cell (03.01.2024)
Published in Protein & cell (03.01.2024)
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Abstract 1951: SMAC mimetic and BET inhibitor - a promising combination for solid cancer treatment
Traexler, Paula-Elena, Arnold, Dominik, Ebner, Florian, Slavic-Obradovic, Ksenija, Jacob, Robin, Thanh, Ha Pham Thi, Aichinger, Martin, Baum, Anke, Wernitznig, Andreas, Gerlach, Daniel, Impagnatiello, Maria-Antonietta, Santoro, Valeria, Olt, Sabine, Scharn, Dirk, Ruzicka, Regina, House, Reniqua P., Murphy, Mary Y., Reiser, Ulrich, Engelhardt, Harald, Zinzalla, Vittoria, Laux, Thorsten, Solca, Flavio, Tontsch-Grunt, Ulrike
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 6221: Targeting IAP in cancer: BI 891065 a potent small molecule SMAC mimetic that synergizes with immune checkpoint inhibition
Aichinger, Martin, Santoro, Valeria, Slavic-Obradovic, Ksenija, Ruhland, Stefanie, Wernitznig, Andreas, Neudolt, Andrea, Schaefer, Markus, Kallenda, Sabine, Zach, Daniel, Olt, Sabine, Salomon, Carina, Rieser, Sarah, Weissenboeck, Martina, Ebner, Florian, Schlattl, Andreas, De Almeida, Melanie Talata, Langlois, Rebecca, Sykora, Martina, Reschke, Markus, Zichner, Thomas, Gerlach, Daniel, Jude, Julian, Fellner, Michaela, Scharn, Dirk, Kraut, Norbert, Moll, Juergen, Zuber, Johannes, Carotta, Sebastian, Impagnatiello, Maria Antonietta, Tontsch-Grunt, Ulrike
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases
Sini, Patrizia, Gürtler, Ulrich, Zahn, Stephan K, Baumann, Christoph, Rudolph, Dorothea, Baumgartinger, Rosa, Strauss, Eva, Haslinger, Christian, Tontsch-Grunt, Ulrike, Waizenegger, Irene C, Solca, Flavio, Bader, Gerd, Zoephel, Andreas, Treu, Matthias, Reiser, Ulrich, Garin-Chesa, Pilar, Boehmelt, Guido, Kraut, Norbert, Quant, Jens, Adolf, Günther R
Published in Molecular cancer therapeutics (01.10.2016)
Published in Molecular cancer therapeutics (01.10.2016)
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