YAP‐TEAD inhibition is associated with upregulation of an androgen receptor mediated transcription program providing therapeutic escape
Alva‐Ruiz, Roberto, Watkins, Ryan D., Tomlinson, Jennifer L., Yonkus, Jennifer A., Abdelrahman, Amro M., Conboy, Caitlin B., Jessen, Erik, Werneburg, Nathan W., Kuipers, Hendrien, Sample, Jack W., Gores, Gregory J., Ilyas, Sumera I., Truty, Mark J., Smoot, Rory L.
Published in FEBS open bio (01.11.2024)
Published in FEBS open bio (01.11.2024)
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Journal Article
Metabolome-wide association identifies altered metabolites and metabolic pathways in the serum of patients with cholangiocarcinoma
Jackson, Linsey E., Tomlinson, Jennifer L., Alva-Ruiz, Roberto, Gregory, Lindsey A., Byeon, Seul Kee, Abdelrahman, Amro M., Mun, Dong-Gi, Grant, Caroline W., Fogarty, Zachary C., Wang, Chen, Roberts, Lewis R., Graham, Rondell P., Borad, Mitesh J., Ilyas, Sumera I., Gores, Gregory J., Pandey, Akhilesh, Athreya, Arjun P., Smoot, Rory L.
Published in JHEP reports (01.06.2024)
Published in JHEP reports (01.06.2024)
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Journal Article
SHP2 inhibition enhances Yes-associated protein–mediated liver regeneration in murine partial hepatectomy models
Watkins, Ryan D., Buckarma, EeeLN H., Tomlinson, Jennifer L., McCabe, Chantal E., Yonkus, Jennifer A., Werneburg, Nathan W., Bayer, Rachel L., Starlinger, Patrick P., Robertson, Keith D., Wang, Chen, Gores, Gregory J., Smoot, Rory L.
Published in JCI insight (08.08.2022)
Published in JCI insight (08.08.2022)
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Journal Article
Diversity of post-translational modifications and cell signaling revealed by single cell and single organelle mass spectrometry
Mun, Dong-Gi, Bhat, Firdous A., Joshi, Neha, Sandoval, Leticia, Ding, Husheng, Jain, Anu, Peterson, Jane A., Kang, Taewook, Pujari, Ganesh P., Tomlinson, Jennifer L., Budhraja, Rohit, Zenka, Roman M., Kannan, Nagarajan, Kipp, Benjamin R., Dasari, Surendra, Gaspar-Maia, Alexandre, Smoot, Rory L., Kandasamy, Richard K., Pandey, Akhilesh
Published in Communications biology (19.07.2024)
Published in Communications biology (19.07.2024)
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Journal Article
Immunobiology of cholangiocarcinoma
Tomlinson, Jennifer L., Valle, Juan W., Ilyas, Sumera I.
Published in Journal of hepatology (01.09.2023)
Published in Journal of hepatology (01.09.2023)
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Journal Article
Hepatology highlights
Tomlinson, Jennifer L., Penrice, Daniel D., Ramkissoon, Resham, Udompap, Prowpanga, Arab, Juan Pablo
Published in Hepatology (Baltimore, Md.) (01.11.2022)
Published in Hepatology (Baltimore, Md.) (01.11.2022)
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Journal Article
Hepatology Highlights
Tomlinson, Jennifer L., Ahn, Joseph C., Povero, Davide, Ramkissoon, Resham, Ilyas, Sumera I., Arab, Juan Pablo
Published in Hepatology (Baltimore, Md.) (01.04.2022)
Published in Hepatology (Baltimore, Md.) (01.04.2022)
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Journal Article
Syngeneic murine models with distinct immune microenvironments represent subsets of human intrahepatic cholangiocarcinoma
Tomlinson, Jennifer L., Li, Binbin, Yang, Jingchun, Loeuillard, Emilien, Stumpf, Hannah E., Kuipers, Hendrien, Watkins, Ryan, Carlson, Danielle M., Willhite, Jessica, O’Brien, Daniel R., Graham, Rondell P., Chen, Xin, Smoot, Rory L., Dong, Haidong, Gores, Gregory J., Ilyas, Sumera I.
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
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Journal Article
Baseline Characteristics and Use of Pretherapeutic 18F-Fluorodeoxyglucose-PET for Pancreatic Cancer
Carlson, Danielle M, Abdelrahman, Amro M, Adjei Antwi, Stella K, Tomlinson, Jennifer L, Trivedi, Kamaxi, Karbhari, Aashna, Patnam Gopal Chetty, Nandakumar, Halfdanarson, Thor R, Goenka, Ajit H, Truty, Mark J
Published in Journal of the American College of Surgeons (01.07.2024)
Published in Journal of the American College of Surgeons (01.07.2024)
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Journal Article
LCK inhibition downregulates YAP activity and is therapeutic in patient-derived models of cholangiocarcinoma
Conboy, Caitlin B., Yonkus, Jennifer A., Buckarma, EeeLN H., Mun, Dong-Gi, Werneburg, Nathan W., Watkins, Ryan D., Alva-Ruiz, Roberto, Tomlinson, Jennifer L., Guo, Yi, Wang, Juan, O’Brien, Daniel, McCabe, Chantal E., Jessen, Erik, Graham, Rondell P., Buijsman, Rogier C., Vu, Diep, de Man, Jos, Ilyas, Sumera I., Truty, Mark J., Borad, Mitesh, Pandey, Akhilesh, Gores, Gregory J., Smoot, Rory L.
Published in Journal of hepatology (01.01.2023)
Published in Journal of hepatology (01.01.2023)
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Journal Article
Outcomes of pancreatectomy with portomesenteric venous resection and reconstruction for locally advanced pancreatic neuroendocrine neoplasms
Gudmundsdottir, Hallbera, Tomlinson, Jennifer L., Graham, Rondell P., Thiels, Cornelius A., Warner, Susanne G., Smoot, Rory L., Kendrick, Michael L., Nagorney, David M., Halfdanarson, Thorvardur R., Habermann, Elizabeth B., Truty, Mark J., Cleary, Sean P.
Published in HPB (Oxford, England) (01.07.2022)
Published in HPB (Oxford, England) (01.07.2022)
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Journal Article
Noncanonical TRAIL Signaling Promotes Myeloid-Derived Suppressor Cell Abundance and Tumor Growth in Cholangiocarcinoma
Loeuillard, Emilien J., Li, Binbin, Stumpf, Hannah E., Yang, Jingchun, Willhite, Jessica R., Tomlinson, Jennifer L., Rohakhtar, Fred Rakhshan, Simon, Vernadette A., Graham, Rondell P., Smoot, Rory L., Dong, Haidong, Ilyas, Sumera I.
Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
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Journal Article
LCK and resistance to cytotoxic chemotherapy via activating an AXL-PEAK1 signaling axis in cholangiocarcinoma
Takaichi, Shohei, Mun, Dong-Gi, Yu, Mincheng, Tomlinson, Jennifer L, Abdelrahman, Amro M, Carlson, Danielle M, Werneburg, Nathan W, Wu, Xinyan, Pandey, Akhilesh, Gores, Gregory J, Smoot, Rory L
Published in JCO global oncology (01.08.2023)
Published in JCO global oncology (01.08.2023)
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Journal Article
Effect of AXL on cholangiocarcinoma survival and sensitivity to cytotoxic chemotherapy
Takaichi, Shohei, Tomlinson, Jennifer L, Yu, Mincheng, Abdelrahman, Amro M, Werneburg, Nathan W, Gores, Gregory J, Smoot, Rory L
Published in Journal of clinical oncology (01.02.2023)
Published in Journal of clinical oncology (01.02.2023)
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Journal Article
Abstract 5753: Milk-derived extracellular nanovesicles: A novel delivery strategy for transcriptome targeting therapies in cholangiocarcinoma
Sample, Jack W., Yu, Mincheng, Kuipers, Hendrien, Carlson, Danielle M., Werneberg, Nathan W., Tomlinson, Jennifer L., Gores, Gregory J., Smoot, Rory L.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract A048: Novel murine models of ARID1A and PBRM1-deficient cholangiocarcinoma for preclinical discovery and development
Conboy, Caitlin B., Tomlinson, Jennifer L., Watkins, Ryan D., Millender, Jayla T., Carlson, Danielle M., Smoot, Rory L., Robertson, Keith D., Gores, Greg J.
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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Journal Article
Baseline Characteristics and Use of Pretherapeutic 18 F-Fluorodeoxyglucose-PET for Pancreatic Cancer
Carlson, Danielle M, Abdelrahman, Amro M, Adjei Antwi, Stella K, Tomlinson, Jennifer L, Trivedi, Kamaxi, Karbhari, Aashna, Patnam Gopal Chetty, Nandakumar, Halfdanarson, Thor R, Goenka, Ajit H, Truty, Mark J
Published in Journal of the American College of Surgeons (01.07.2024)
Published in Journal of the American College of Surgeons (01.07.2024)
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Journal Article
Abstract 614: Src family kinase inhibition demonstrates antitumor activity in vitro and in patient-derived xenograft models of human cholangiocarcinoma
Kuipers, Hendrien, Tomlinson, Jennifer L., Carlson, Danielle M., Abdelrahman, Amro M., Jessen, Erik, Sample, Jack W., Werneburg, Nathan W., Stumpf, Hannah E., Truty, Mark J., Ilyas, Sumera I., Gores, Gregory J., Smoot, Rory L.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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