Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase
FREZZA, Christian, LIANG ZHENG, KALNA, Gabriela, TOMLINSON, Ian P. M, POLLARD, Patrick J, WATSON, Dave G, DEBERARDINIS, Ralph J, SHLOMI, Tomer, RUPPIN, Eytan, GOTTLIEB, Eyal, FOLGER, Ori, RAJAGOPALAN, Kartik N, MACKENZIE, Elaine D, JERBY, Livnat, MICARONI, Massimo, CHANETON, Barbara, ADAM, Julie, HEDLEY, Ann
Published in Nature (London) (08.09.2011)
Published in Nature (London) (08.09.2011)
Get full text
Journal Article
Prognostic significance of POLE proofreading mutations in endometrial cancer
Church, David N, Stelloo, Ellen, Nout, Remi A, Valtcheva, Nadejda, Depreeuw, Jeroen, ter Haar, Natalja, Noske, Aurelia, Amant, Frederic, Tomlinson, Ian P M, Wild, Peter J, Lambrechts, Diether, Jürgenliemk-Schulz, Ina M, Jobsen, Jan J, Smit, Vincent T H B M, Creutzberg, Carien L, Bosse, Tjalling
Published in JNCI : Journal of the National Cancer Institute (01.01.2015)
Published in JNCI : Journal of the National Cancer Institute (01.01.2015)
Get full text
Journal Article
Measuring single cell divisions in human tissues from multi-region sequencing data
Werner, Benjamin, Case, Jack, Williams, Marc J, Chkhaidze, Ketevan, Temko, Daniel, Fernández-Mateos, Javier, Cresswell, George D, Nichol, Daniel, Cross, William, Spiteri, Inmaculada, Huang, Weini, Tomlinson, Ian P M, Barnes, Chris P, Graham, Trevor A, Sottoriva, Andrea
Published in Nature communications (25.02.2020)
Published in Nature communications (25.02.2020)
Get full text
Journal Article
Chromosomal Instability Confers Intrinsic Multidrug Resistance
LEE, Alvin J. X, ENDESFELDER, David, KSCHISCHO, Maik, SWANTON, Charles, ROWAN, Andrew J, WALTHER, Axel, BIRKBAK, Nicolai J, ANDREW FUTREAL, P, DOWNWARD, Julian, SZALLASI, Zoltan, TOMLINSON, Ian P. M, HOWELL, Michael
Published in Cancer research (Chicago, Ill.) (01.03.2011)
Published in Cancer research (Chicago, Ill.) (01.03.2011)
Get full text
Journal Article
Genomic Evolution and Transcriptional Changes in the Evolution of Prostate Cancer into Neuroendocrine and Ductal Carcinoma Types
Rao, Srinivasa R, Protheroe, Andrew, Cerundolo, Lucia, Maldonado-Perez, David, Browning, Lisa, Lamb, Alastair D, Bryant, Richard J, Mills, Ian G, Woodcock, Dan J, Hamdy, Freddie C, Tomlinson, Ian P M, Verrill, Clare
Published in International journal of molecular sciences (01.08.2023)
Published in International journal of molecular sciences (01.08.2023)
Get full text
Journal Article
PHLDA1 Expression Marks the Putative Epithelial Stem Cells and Contributes to Intestinal Tumorigenesis
SAKTHIANANDESWAREN, Anuratha, CHRISTIE, Michael, RAMSAY, Robert G, PHESSE, Toby J, ERNST, Matthias, JEFFERY, Rosemary E, POULSOM, Richard, LEEDHAM, Simon J, SEGDITSAS, Stefania, TOMLINSON, Ian P. M, BERNHARD, Oliver K, SIMPSON, Richard J, D'ANDRETI, Carla, WALKER, Francesca, FAUX, Maree C, CHURCH, Nicole, CATIMEL, Bruno, FLANAGAN, Dustin J, VINCAN, Elizabeth, SIEBER, Oliver M, TSUI, Cary, JORISSEN, Robert N, SHAN LI, FLEMING, Nicholas I, GIBBS, Peter, LIPTON, Lara, MALATERRE, Jordane
Published in Cancer research (Chicago, Ill.) (15.05.2011)
Published in Cancer research (Chicago, Ill.) (15.05.2011)
Get full text
Journal Article
The stem cell marker CD133 associates with enhanced colony formation and cell motility in colorectal cancer
Elsaba, Tarek M A, Martinez-Pomares, Luisa, Robins, Adrian R, Crook, Simon, Seth, Rashmi, Jackson, Darryl, McCart, Amy, Silver, Andrew R, Tomlinson, Ian P M, Ilyas, Mohammad
Published in PloS one (19.05.2010)
Published in PloS one (19.05.2010)
Get full text
Journal Article
Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas
DOUGLAS, Eleanor J, FIEGLER, Heike, ROWAN, Andrew, HALFORD, Sarah, BICKNELL, David C, BODMER, Walter, TOMLINSON, Ian P. M, CARTER, Nigel P
Published in Cancer research (Chicago, Ill.) (15.07.2004)
Published in Cancer research (Chicago, Ill.) (15.07.2004)
Get full text
Journal Article
Antibody arrays for high-throughput screening of antibody-antigen interactions
de Wildt, Ruud M. T, Tomlinson, Ian M, Mundy, Chris R, Gorick, Barbara D
Published in Nature biotechnology (01.09.2000)
Published in Nature biotechnology (01.09.2000)
Get full text
Journal Article
Evaluation of PIK3CA Mutation As a Predictor of Benefit From Nonsteroidal Anti-Inflammatory Drug Therapy in Colorectal Cancer
DOMINGO, Enric, CHURCH, David N, SIEBER, Oliver, RAMAMOORTHY, Rajarajan, YANAGISAWA, Yoko, JOHNSTONE, Elaine, DAVIDSON, Brian, KERR, David J, TOMLINSON, Ian P. M, MIDGLEY, Rachel
Published in Journal of clinical oncology (01.12.2013)
Published in Journal of clinical oncology (01.12.2013)
Get full text
Journal Article
Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
MOURADOV, Dmitri, SLOGGETT, Clare, O'CONNOR, Liam, WILDING, Jennifer L, BICKNELL, David, TOMLINSON, Ian P. M, BODMER, Walter F, MARIADASON, John M, SIEBER, Oliver M, JORISSEN, Robert N, LOVE, Christopher G, SHAN LI, BURGESS, Antony W, ARANGO, Diego, STRAUSBERG, Robert L, BUCHANAN, Daniel, WORMALD, Samuel
Published in Cancer research (Chicago, Ill.) (15.06.2014)
Published in Cancer research (Chicago, Ill.) (15.06.2014)
Get full text
Journal Article
What can be learnt about disease progression in breast cancer dormancy from relapse data?
Willis, Lisa, Graham, Trevor A, Alarcón, Tomás, Alison, Malcolm R, Tomlinson, Ian P M, Page, Karen M
Published in PloS one (06.05.2013)
Published in PloS one (06.05.2013)
Get full text
Journal Article
Adult Leydig Cell Tumors of the Testis Caused by Germline Fumarate Hydratase Mutations
Carvajal-Carmona, Luis G, Alam, N. Afrina, Pollard, Patrick J, Jones, Angela M, Barclay, Ella, Wortham, Noel, Pignatelli, Massimo, Freeman, Alex, Pomplun, Sabine, Ellis, Ian, Poulsom, Richard, El-Bahrawy, Mona A, Berney, Daniel M, Tomlinson, Ian P. M
Published in The journal of clinical endocrinology and metabolism (01.08.2006)
Published in The journal of clinical endocrinology and metabolism (01.08.2006)
Get full text
Journal Article
Multiple Rare Variants in Different Genes Account for Multifactorial Inherited Susceptibility to Colorectal Adenomas
Fearnhead, Nicola S., Wilding, Jennifer L., Winney, Bruce, Tonks, Susan, Bartlett, Sylvia, Bicknell, David C., Ian P. M. Tomlinson, Neil J. Mc C. Mortensen, Bodmer, Walter F.
Published in Proceedings of the National Academy of Sciences - PNAS (09.11.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (09.11.2004)
Get full text
Journal Article
Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study
Zhang, Xiaomeng, Theodoratou, Evropi, Li, Xue, Farrington, Susan M, Law, Philip J, Broderick, Peter, Walker, Marion, Klimentidis, Yann C, Rees, Jessica M B, Houlston, Richard S, Tomlinson, Ian P M, Burgess, Stephen, Campbell, Harry, Dunlop, Malcolm G, Timofeeva, Maria
Published in British journal of cancer (30.03.2021)
Published in British journal of cancer (30.03.2021)
Get full text
Journal Article
Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank
Zhang, Xiaomeng, Li, Xue, He, Yazhou, Law, Philip J, Farrington, Susan M, Campbell, Harry, Tomlinson, Ian P M, Houlston, Richard S, Dunlop, Malcolm G, Timofeeva, Maria, Theodoratou, Evropi
Published in British journal of cancer (23.03.2022)
Published in British journal of cancer (23.03.2022)
Get full text
Journal Article