Fluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways
Chisholm, David R, Tomlinson, Charles W. E, Zhou, Garr-Layy, Holden, Claire, Affleck, Valerie, Lamb, Rebecca, Newling, Katherine, Ashton, Peter, Valentine, Roy, Redfern, Christopher, Erostyák, János, Makkai, Geza, Ambler, Carrie A, Whiting, Andrew, Pohl, Ehmke
Published in ACS chemical biology (15.03.2019)
Published in ACS chemical biology (15.03.2019)
Get full text
Journal Article
Novel Fluorescence Competition Assay for Retinoic Acid Binding Proteins
Tomlinson, Charles W. E, Chisholm, David R, Valentine, Roy, Whiting, Andrew, Pohl, Ehmke
Published in ACS medicinal chemistry letters (13.12.2018)
Published in ACS medicinal chemistry letters (13.12.2018)
Get full text
Journal Article
Structure–functional relationship of cellular retinoic acid‐binding proteins I and II interacting with natural and synthetic ligands
Tomlinson, Charles W. E., Cornish, Katy A. S., Whiting, Andrew, Pohl, Ehmke
Published in Acta crystallographica. Section D, Biological crystallography. (01.02.2021)
Published in Acta crystallographica. Section D, Biological crystallography. (01.02.2021)
Get full text
Journal Article
Prognostic Importance of Myocardial Ischemia Detected by Ambulatory Monitoring Early after Acute Myocardial Infarction
Gill, John B, Cairns, John A, Roberts, Robin S, Costantini, Lorrie, Sealey, Brian J, Fallen, Ernest F, Tomlinson, Charles W, Gent, Michael
Published in The New England journal of medicine (11.01.1996)
Published in The New England journal of medicine (11.01.1996)
Get full text
Journal Article
A case of primary malignant pericardial mesothelioma
Lagrotteria, Danny D, Tsang, Bernice, Elavathil, Leelama J, Tomlinson, Charles W
Published in Canadian journal of cardiology (01.02.2005)
Get more information
Published in Canadian journal of cardiology (01.02.2005)
Journal Article
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
Boby, Melissa L, Fearon, Daren, Ferla, Matteo, Filep, Mihajlo, Koekemoer, Lizbé, Robinson, Matthew C, Chodera, John D, Lee, Alpha A, London, Nir, von Delft, Annette, von Delft, Frank, Achdout, Hagit, Aimon, Anthony, Alonzi, Dominic S, Arbon, Robert, Aschenbrenner, Jasmin C, Balcomb, Blake H, Bar-David, Elad, Barr, Haim, Ben-Shmuel, Amir, Bennett, James, Bilenko, Vitaliy A, Borden, Bruce, Boulet, Pascale, Bowman, Gregory R, Brewitz, Lennart, Brun, Juliane, Bvnbs, Sarma, Calmiano, Mark, Carbery, Anna, Carney, Daniel W, Cattermole, Emma, Chang, Edcon, Chernyshenko, Eugene, Clyde, Austin, Coffland, Joseph E, Cohen, Galit, Cole, Jason C, Contini, Alessandro, Cox, Lisa, Croll, Tristan Ian, Cvitkovic, Milan, De Jonghe, Steven, Dias, Alex, Donckers, Kim, Dotson, David L, Douangamath, Alice, Duberstein, Shirly, Dudgeon, Tim, Dunnett, Louise E, Eastman, Peter, Erez, Noam, Eyermann, Charles J, Fairhead, Michael, Fate, Gwen, Fedorov, Oleg, Fernandes, Rafaela S, Ferrins, Lori, Foster, Richard, Foster, Holly, Fraisse, Laurent, Gabizon, Ronen, García-Sastre, Adolfo, Gawriljuk, Victor O, Gehrtz, Paul, Gileadi, Carina, Giroud, Charline, Glass, William G, Glen, Robert C, Glinert, Itai, Godoy, Andre S, Gorichko, Marian, Gorrie-Stone, Tyler, Griffen, Ed J, Haneef, Amna, Hassell Hart, Storm, Heer, Jag, Henry, Michael, Hill, Michelle, Horrell, Sam, Huang, Qiu Yu Judy, Huliak, Victor D, Hurley, Matthew F D, Israely, Tomer, Jajack, Andrew, Jansen, Jitske, Jnoff, Eric, Jochmans, Dirk, John, Tobias, Kaminow, Benjamin, Kang, Lulu, Kantsadi, Anastassia L, Kenny, Peter W, Kiappes, J L, Kinakh, Serhii O, Kovar, Boris, Krojer, Tobias, La, Van Ngoc Thuy, Laghnimi-Hahn, Sophie, Lefker, Bruce A
Published in Science (American Association for the Advancement of Science) (10.11.2023)
Published in Science (American Association for the Advancement of Science) (10.11.2023)
Get full text
Journal Article
Structural requirements for the specific binding of CRABP2 to cyclin D3
Pastok, Martyna W., Tomlinson, Charles W.E., Turberville, Shannon, Butler, Abbey M., Baslé, Arnaud, Noble, Martin E.M., Endicott, Jane A., Pohl, Ehmke, Tatum, Natalie J.
Published in Structure (London) (26.10.2024)
Published in Structure (London) (26.10.2024)
Get full text
Journal Article
Structural requirements for the specific binding of CRABP2 to cyclin D3
Pastok, Martyna W., Tomlinson, Charles W.E., Turberville, Shannon, Butler, Abbey M., Baslé, Arnaud, Noble, Martin E.M., Endicott, Jane A., Pohl, Ehmke, Tatum, Natalie J.
Published in Structure (London) (16.10.2024)
Published in Structure (London) (16.10.2024)
Get full text
Journal Article
Accelerated care versus standard care among patients with hip fracture: the HIP ATTACK pilot trial
Published in Canadian Medical Association journal (CMAJ)
(07.01.2014)
Get full text
Journal Article
Identifying novel chemical matter against the Chikungunya virus nsP3 macrodomain through crystallographic fragment screening
Aschenbrenner, Jasmin C, de Godoy, Andre Schutzer, Fairhead, Michael, Tomlinson, Charles W E, Winokan, Max, Balcomb, Blake H, Capkin, Eda, Chandran, Anu V, Golding, Mathew, Koekemoer, Lizbe, Lithgo, Ryan M, Marples, Peter G, Ni, Xiaomin, Thompson, Warren, Wild, Conor, Xavier, Mary-Ann E, Fearon, Daren, von Delft, Frank
Published in bioRxiv (23.08.2024)
Published in bioRxiv (23.08.2024)
Get full text
Journal Article
High-throughput crystallographic fragment screening of Zika virus NS3 Helicase
Godoy, Andre S, Mesquita, Nathalya C M R, Noske, Gabriela Dias, Gawriljuk, Victor Oliveira, Lithgo, Ryan M, Balcomb, Blake H, Aschenbrenner, Jasmin Cara, Tomlinson, Charles W E, Winokan, Max, Scheen, Jenke, Marples, Peter George, Chandran, Anu V, Ni, Xiaomin, Thompson, Warren, Fairhead, Michael, Fearon, Daren, Koekemoer, Lizbé, Xavier, Mary-Ann Elvina, Walsh, Martin, Oliva, Glaucius, von Delft, Frank
Published in bioRxiv (29.04.2024)
Published in bioRxiv (29.04.2024)
Get full text
Journal Article
Crystallographic fragment screening delivers diverse chemical scaffolds for Zika virus NS2B-NS3 protease inhibitor development
Ni, Xiaomin, Godoy, Andre Schutzer, Marples, Peter G, Fairhead, Michael, Balcomb, Blake H, Ferla, Matteo P, Tomlinson, Charles W E, Wang, Siyi, Giroud, Charline, Aschenbrenner, Jasmin Cara, Lithgo, Ryan M, Winokan, Max, Chandran, Anu V, Thompson, Warren, Xavier, Mary-Ann, Williams, Eleanor P, Walsh, Martin, Fearon, Daren, Koekemoer, Lizbé, von Delft, Frank
Published in bioRxiv : the preprint server for biology (29.04.2024)
Published in bioRxiv : the preprint server for biology (29.04.2024)
Get more information
Journal Article
Crystallographic Fragment Screen of Coxsackievirus A16 2A Protease identifies new opportunities for the development of broad-spectrum anti-enterovirals
Lithgo, Ryan M, Tomlinson, Charles W E, Fairhead, Michael, Winokan, Max, Thompson, Warren, Wild, Conor, Aschenbrenner, Jasmin Cara, Balcomb, Blake H, Marples, Peter G, Chandran, Anu V, Golding, Mathew, Koekemoer, Lizbe, Williams, Eleanor P, Wang, SiYl, Ni, Xiaomin, MacLean, Elizabeth, Giroud, Charline, Godoy, Andre Schutzer, Xavier, Mary-Ann, Walsh, Martin, Fearon, Daren, von Delft, Frank
Published in bioRxiv : the preprint server for biology (29.04.2024)
Published in bioRxiv : the preprint server for biology (29.04.2024)
Get more information
Journal Article
Discovery of potent SARS-CoV-2 nsp3 macrodomain inhibitors uncovers lack of translation to cellular antiviral response
Lee, Alpha A, Amick, Isabelle, Aschenbrenner, Jasmin C, Barr, Haim M, Benjamin, Jared, Brandis, Alexander, Cohen, Galit, Diaz-Tapia, Randy, Duberstein, Shirly, Dixon, Jessica, Cousins, David, Fairhead, Michael, Fearon, Daren, Frick, James, Gayvert, James, Godoy, Andre S, Griffin, Ed J, Huber, Kilian, Koekemoer, Lizbé, Lahav, Noa, Marples, Peter G, McGovern, Briana L, Mehlman, Tevie, Robinson, Matthew C, Singh, Usha, Szommer, Tamas, Tomlinson, Charles W E, Vargo, Thomas, von Delft, Frank, Wang, SiYi, White, Kris, Williams, Eleanor, Winokan, Max
Published in bioRxiv (21.08.2024)
Published in bioRxiv (21.08.2024)
Get full text
Journal Article