Chromosomal Translocations in Human Cells Are Generated by Canonical Nonhomologous End-Joining
Ghezraoui, Hind, Piganeau, Marion, Renouf, Benjamin, Renaud, Jean-Baptiste, Sallmyr, Annahita, Ruis, Brian, Oh, Sehyun, Tomkinson, Alan E., Hendrickson, Eric A., Giovannangeli, Carine, Jasin, Maria, Brunet, Erika
Published in Molecular cell (18.09.2014)
Published in Molecular cell (18.09.2014)
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Structural basis of long-range to short-range synaptic transition in NHEJ
Chen, Siyu, Lee, Linda, Naila, Tasmin, Fishbain, Susan, Wang, Annie, Tomkinson, Alan E, Lees-Miller, Susan P, He, Yuan
Published in Nature (London) (13.05.2021)
Published in Nature (London) (13.05.2021)
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Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis
Wang, Haibo, Guo, Wenting, Mitra, Joy, Hegde, Pavana M, Vandoorne, Tijs, Eckelmann, Bradley J, Mitra, Sankar, Tomkinson, Alan E, Van Den Bosch, Ludo, Hegde, Muralidhar L
Published in Nature communications (11.09.2018)
Published in Nature communications (11.09.2018)
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Mammalian DNA ligases; roles in maintaining genome integrity
Sallmyr, Annahita, Bhandari, Seema Khattri, Naila, Tasmin, Tomkinson, Alan E.
Published in Journal of molecular biology (01.01.2024)
Published in Journal of molecular biology (01.01.2024)
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Human DNA ligases in replication and repair
Sallmyr, Annahita, Rashid, Ishtiaque, Bhandari, Seema Khattri, Naila, Tasmin, Tomkinson, Alan E.
Published in DNA repair (01.09.2020)
Published in DNA repair (01.09.2020)
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Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase
Sverzhinsky, Aleksandr, Tomkinson, Alan E., Pascal, John M.
Published in Structure (London) (03.03.2022)
Published in Structure (London) (03.03.2022)
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NAD+ is not utilized as a co-factor for DNA ligation by human DNA ligase IV
Zhao, Bailin, Naila, Tasmin, Lieber, Michael R, Tomkinson, Alan E
Published in Nucleic acids research (16.12.2020)
Published in Nucleic acids research (16.12.2020)
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Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1
Bhandari, Seema Khattri, Wiest, Nathaniel, Sallmyr, Annahita, Du, Ruofei, Ferry, Laure, Defossez, Pierre-Antoine, Tomkinson, Alan E
Published in Scientific reports (16.03.2023)
Published in Scientific reports (16.03.2023)
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An atypical BRCT–BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex
Hammel, Michal, Rashid, Ishtiaque, Sverzhinsky, Aleksandr, Pourfarjam, Yasin, Tsai, Miaw-Sheue, Ellenberger, Tom, Pascal, John M, Kim, In-Kwon, Tainer, John A, Tomkinson, Alan E
Published in Nucleic acids research (11.01.2021)
Published in Nucleic acids research (11.01.2021)
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Human DNA Ligase I Interacts with and Is Targeted for Degradation by the DCAF7 Specificity Factor of the Cul4-DDB1 Ubiquitin Ligase Complex
Peng, Zhimin, Liao, Zhongping, Matsumoto, Yoshihiro, Yang, Austin, Tomkinson, Alan E
Published in The Journal of biological chemistry (14.10.2016)
Published in The Journal of biological chemistry (14.10.2016)
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An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex
Hammel, Michal, Yu, Yaping, Radhakrishnan, Sarvan K., Chokshi, Chirayu, Tsai, Miaw-Sheue, Matsumoto, Yoshihiro, Kuzdovich, Monica, Remesh, Soumya G., Fang, Shujuan, Tomkinson, Alan E., Lees-Miller, Susan P., Tainer, John A.
Published in The Journal of biological chemistry (30.12.2016)
Published in The Journal of biological chemistry (30.12.2016)
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FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease
Kodavati, Manohar, Wang, Haibo, Guo, Wenting, Mitra, Joy, Hegde, Pavana M, Provasek, Vincent, Rao, Vikas H Maloji, Vedula, Indira, Zhang, Aijun, Mitra, Sankar, Tomkinson, Alan E, Hamilton, Dale J, Van Den Bosch, Ludo, Hegde, Muralidhar L
Published in Nature communications (09.03.2024)
Published in Nature communications (09.03.2024)
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