In vitro Activation of CPP32 and Mch3 by Mch4, a Novel Human Apoptotic Cysteine Protease Containing Two FADD-Like Domains
Fernandes-Alnemri, Teresa, Armstrong, Robert C., Krebs, Joseph, Srinivasula, Srinivasa M., Wang, Lijuan, Bullrich, Florencia, Fritz, Lawrence C., Trapani, Joseph A., Tomaselli, Kevin J., Litwack, Gerald, Alnemri, Emad S.
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.1996)
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ATP-dependent steps in apoptotic signal transduction
EGUCHI, Y, SRINIVASAN, A, TOMASELLI, K. J, SHIMIZU, S, TSUJIMOTO, Y
Published in Cancer research (Chicago, Ill.) (01.05.1999)
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Published in Cancer research (Chicago, Ill.) (01.05.1999)
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Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro
SIMMONS, L. K, MAY, P. C, WEI YING LI, TOMASELLI, K. J, RYDEL, R. E, FUSON, K. S, BRIGHAM, E. F, WRIGHT, S, LIEBERBURG, I, BECKER, G. W, BREMS, D. N
Published in Molecular pharmacology (01.03.1994)
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Published in Molecular pharmacology (01.03.1994)
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A Cell Culture Model of the Blood-Brain Barrier
Rubin, L. L., Hall, D. E., Porter, S., Barbu, K., Cannon, C., Horner, H. C., Janatpour, M., Liaw, C. W., Manning, K., Morales, J., Tanner, L. I., Tomaselli, K. J., Bard, F.
Published in The Journal of cell biology (01.12.1991)
Published in The Journal of cell biology (01.12.1991)
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Mch3, a novel human apoptotic cysteine protease highly related to CPP32
FERNANDEZ-ALNEMRI, T, TAKAHASHI, A, EARNSHAW, W. C, LITWACK, G, ALNEMRI, E. S, ARMSTRONG, R, KREBS, J, FRITZ, L, TOMASELLI, K. J, LIJUAN WANG, ZAILIN YU, CROCE, C. M, SALVESON, G
Published in Cancer research (Chicago, Ill.) (15.12.1995)
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Published in Cancer research (Chicago, Ill.) (15.12.1995)
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The Ced-3/Interleukin 1β Converting Enzyme-like Homolog Mch6 and the Lamin-cleaving Enzyme Mch2α Are Substrates for the Apoptotic Mediator CPP32
Srinivasula, Srinivasa M., Fernandes-Alnemri, Teresa, Zangrilli, James, Robertson, Noreen, Armstrong, Robert C., Wang, Lijuan, Trapani, Joseph A., Tomaselli, Kevin J., Litwack, Gerald, Alnemri, Emad S.
Published in The Journal of biological chemistry (1996)
Published in The Journal of biological chemistry (1996)
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Peptide inhibitors of the ice protease family arrest programmed cell death of motoneurons in vivo and in vitro
Milligan, C.E., Prevette, D., Yaginuma, H., Homma, S., Cardwellt, C., Fritz, L.C., Tomaselli, K.J., Oppenheim, R.W., Schwartz, L.M.
Published in Neuron (Cambridge, Mass.) (01.08.1995)
Published in Neuron (Cambridge, Mass.) (01.08.1995)
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DNA Damage and Activated Caspase-3 Expression in Neurons and Astrocytes: Evidence for Apoptosis in Frontotemporal Dementia
Su, Joseph H., Nichol, Kathryn E., Sitch, Tom, Sheu, Philip, Chubb, Charlie, Miller, Bruce L., Tomaselli, Kevin J., Kim, Ronald C., Cotman, Carl W.
Published in Experimental neurology (01.05.2000)
Published in Experimental neurology (01.05.2000)
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Conference Proceeding
Apoptotic suppression by baculovirus P35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease
Bertin, J, Mendrysa, S M, LaCount, D J, Gaur, S, Krebs, J F, Armstrong, R C, Tomaselli, K J, Friesen, P D
Published in Journal of Virology (01.09.1996)
Published in Journal of Virology (01.09.1996)
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N-Cadherin, NCAM, and Integrins Promote Retinal Neurite Outgrowth on Astrocytes in Vitro
Neugebauer, Karla M., Tomaselli, Kevin J., Lilien, Jack, Reichardt, Louis F.
Published in The Journal of cell biology (01.09.1988)
Published in The Journal of cell biology (01.09.1988)
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Bovine herpesvirus 4 BORFE2 protein inhibits Fas- and tumor necrosis factor receptor 1-induced apoptosis and contains death effector domains shared with other gamma-2 herpesviruses
Wang, G H, Bertin, J, Wang, Y, Martin, D A, Wang, J, Tomaselli, K J, Armstrong, R C, Cohen, J I
Published in Journal of Virology (01.11.1997)
Published in Journal of Virology (01.11.1997)
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Activation of Caspase‐3 in Developmental Models of Programmed Cell Death in Neurons of the Substantia Nigra
Jeon, Beom S., Kholodilov, Nikolai G., Oo, Tinmarla F., Kim, Sang‐Yun, Tomaselli, Kevin J., Srinivasan, Anu, Stefanis, Leonidas, Burke, Robert E.
Published in Journal of neurochemistry (01.07.1999)
Published in Journal of neurochemistry (01.07.1999)
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Structure of Recombinant Human CPP32 in Complex with the Tetrapeptide Acetyl-Asp-Val-Ala-Asp Fluoromethyl Ketone
Mittl, Peer R.E., Di Marco, Stefania, Krebs, Joseph F., Bai, Xu, Karanewsky, Donald S., Priestle, John P., Tomaselli, Kevin J., Grütter, Markus G.
Published in The Journal of biological chemistry (07.03.1997)
Published in The Journal of biological chemistry (07.03.1997)
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Interactions of a Neuronal Cell Line (PC12) with Laminin, Collagen IV, and Fibronectin: Identification of Integrin-Related Glycoproteins Involved in Attachment and Process Outgrowth
Tomaselli, Kevin J., Damsky, Caroline H., Reichardt, Louis F.
Published in The Journal of cell biology (01.11.1987)
Published in The Journal of cell biology (01.11.1987)
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Two CD95 (APO-1/Fas) signaling pathways
Scaffidi, Carsten, Fulda, Simone, Srinivasan, Anu, Friesen, Claudia, Li, Feng, Tomaselli, Kevin J., Debatin, Klaus-Michael, Krammer, Peter H., Peter, Marcus E.
Published in The EMBO journal (16.03.1998)
Published in The EMBO journal (16.03.1998)
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Purification and Characterization of Mammalian Integrins Expressed by a Rat Neuronal Cell Line (PC12): Evidence That They Function as α/β Heterodimeric Receptors for Laminin and Type IV Collagen
Tomaselli, Kevin J., Damsky, Caroline H., Reichardt, Louis F.
Published in The Journal of cell biology (01.09.1988)
Published in The Journal of cell biology (01.09.1988)
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Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
Strasser, Andreas, Marsden, Vanessa S, O'Connor, Liam, O'Reilly, Lorraine A, Silke, John, Metcalf, Donald, Ekert, Paul G, Huang, David C. S, Cecconi, Francesco, Kuida, Keisuke, Tomaselli, Kevin J, Roy, Sophie, Nicholson, Don W, Vaux, David L, Bouillet, Philippe, Adams, Jerry M
Published in Nature (London) (10.10.2002)
Published in Nature (London) (10.10.2002)
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Conformationally constrained inhibitors of caspase-1 (interleukin-1β converting enzyme) and of the human ced-3 homologue caspase-3 (CPP32, apopain)
Karanewsky, Donald S., Bai, Xu, Linton, Steven D., Krebs, Joseph F., Wu, Joe, Pham, Bryan, Tomaselli, Kevin J.
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
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Activation and Cleavage of Caspase-3 in Apoptosis Induced by Experimental Cerebral Ischemia
Namura, Shobu, Zhu, Jinmin, Fink, Klaus, Endres, Matthias, Srinivasan, Anu, Tomaselli, Kevin J, Yuan, Junying, Moskowitz, Michael A
Published in The Journal of neuroscience (15.05.1998)
Published in The Journal of neuroscience (15.05.1998)
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