Clonal medicine targeting DNA damage response eradicates leukemia
Toma, Monika M., Karami, Adam, Nieborowska-Skorska, Margaret, Chirtala, Kumaraswamy Naidu, Pepek, Monika, Hadzijusufovic, Emir, Stoklosa, Tomasz, Valent, Peter, Skorski, Tomasz
Published in Leukemia (01.03.2024)
Published in Leukemia (01.03.2024)
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Journal Article
Simultaneous Targeting of DNA Polymerase Theta and PARP1 or RAD52 Triggers Dual Synthetic Lethality in Homologous Recombination-Deficient Leukemia Cells
Sullivan-Reed, Katherine, Toma, Monika M, Drzewiecka, Malgorzata, Nieborowska-Skorska, Margaret, Nejati, Reza, Karami, Adam, Wasik, Mariusz A, Sliwinski, Tomasz, Skorski, Tomasz
Published in Molecular cancer research (02.10.2023)
Published in Molecular cancer research (02.10.2023)
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Journal Article
DNA Double Strand Break Repair - Related Synthetic Lethality
Toma, Monika, Skorski, Tomasz, Sliwinski, Tomasz
Published in Current medicinal chemistry (01.01.2019)
Published in Current medicinal chemistry (01.01.2019)
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Journal Article
4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
Calbert, Marissa, Chandramouly, Gurushankar, Adams, Clare, Saez-Ayala, Magali, Kent, Tatiana, Tyagi, Mrityunjay, Ayyadevara, V.S.S. Abhinav, Wang, Yifan, Krais, John, Gordon, John, Atkins, Jessica, Toma, Monika, Betzi, Stéphane, Boghossian, Andrew, Rees, Matthew, Ronan, Melissa, Roth, Jennifer, Goldman, Aaron, Gorman, Nicole, Mitra, Ramkrishna, Childers, Wayne, Graña, Xavier, Skorski, Tomasz, Johnson, Neil, Hurtz, Christian, Morelli, Xavier, Eischen, Christine, Pomerantz, Richard
Published in Molecular cancer therapeutics (02.05.2024)
Published in Molecular cancer therapeutics (02.05.2024)
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Journal Article
Impact of Single Nucleotide Polymorphisms of Base Excision Repair Genes on DNA Damage and Efficiency of DNA Repair in Recurrent Depression Disorder
Czarny, Piotr, Kwiatkowski, Dominik, Toma, Monika, Kubiak, Joanna, Sliwinska, Agnieszka, Talarowska, Monika, Szemraj, Janusz, Maes, Michael, Galecki, Piotr, Sliwinski, Tomasz
Published in Molecular neurobiology (01.08.2017)
Published in Molecular neurobiology (01.08.2017)
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Journal Article
4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
Calbert, Marissa L, Chandramouly, Gurushankar, Adams, Clare M, Saez-Ayala, Magali, Kent, Tatiana, Tyagi, Mrityunjay, Ayyadevara, V S S Abhinav, Wang, Yifan, Krais, John J, Gordon, John, Atkins, Jessica, Toma, Monika M, Betzi, Stéphane, Boghossian, Andrew S, Rees, Matthew G, Ronan, Melissa M, Roth, Jennifer A, Goldman, Aaron R, Gorman, Nicole, Mitra, Ramkrishna, Childers, Wayne E, Graña, Xavier, Skorski, Tomasz, Johnson, Neil, Hurtz, Christian, Morelli, Xavier, Eischen, Christine M, Pomerantz, Richard T
Published in Molecular cancer therapeutics (02.05.2024)
Published in Molecular cancer therapeutics (02.05.2024)
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Journal Article
Insight the Biological Activities of Selected Abietane Diterpenes Isolated from Plectranthus spp
Sitarek, Przemysław, Toma, Monika, Ntungwe, Epole, Kowalczyk, Tomasz, Skała, Ewa, Wieczfinska, Joanna, Śliwiński, Tomasz, Rijo, Patricia
Published in Biomolecules (Basel, Switzerland) (28.01.2020)
Published in Biomolecules (Basel, Switzerland) (28.01.2020)
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Journal Article
Non-NAD-like PARP1 inhibitor enhanced synthetic lethal effect of NAD-like PARP inhibitors against BRCA1-deficient leukemia
Nieborowska-Skorska, Margaret, Maifrede, Silvia, Ye, Min, Toma, Monika, Hewlett, Elizabeth, Gordon, John, Le, Bac Viet, Sliwinski, Tomasz, Zhao, Huaqing, Piwocka, Katarzyna, Valent, Peter, Tulin, Alexei V., Childers, Wayne, Skorski, Tomasz
Published in Leukemia & lymphoma (21.03.2019)
Published in Leukemia & lymphoma (21.03.2019)
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Journal Article
An Extract of Transgenic Senna obtusifolia L. Hairy Roots with Overexpression of PgSS1 Gene in Combination with Chemotherapeutic Agent Induces Apoptosis in the Leukemia Cell Line
Kowalczyk, Tomasz, Sitarek, Przemysław, Toma, Monika, Picot, Laurent, Wielanek, Marzena, Skała, Ewa, Śliwiński, Tomasz
Published in Biomolecules (Basel, Switzerland) (01.04.2020)
Published in Biomolecules (Basel, Switzerland) (01.04.2020)
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Journal Article
Associations between DNA Damage, DNA Base Excision Repair Gene Variability and Alzheimer's Disease Risk
Kwiatkowski, Dominik, Czarny, Piotr, Toma, Monika, Jurkowska, Natalia, Sliwinska, Agnieszka, Drzewoski, Jozef, Bachurska, Agnieszka, Szemraj, Janusz, Maes, Michael, Berk, Michael, Su, Kuan-Pin, Galecki, Piotr, Sliwinski, Tomasz
Published in Dementia and geriatric cognitive disorders (01.01.2016)
Published in Dementia and geriatric cognitive disorders (01.01.2016)
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Journal Article
Novel allosteric PARP1 inhibitors for the treatment of BRCA-deficient leukemia
Hewlett, Elizabeth, Toma, Monika, Sullivan-Reed, Katherine, Gordon, John, Sliwinski, Tomasz, Tulin, Alexei, Childers, Wayne E., Skorski, Tomasz
Published in Medicinal chemistry research (01.06.2020)
Published in Medicinal chemistry research (01.06.2020)
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Journal Article
Association between Single-Nucleotide Polymorphisms of the hOGG1,NEIL1,APEX1, FEN1,LIG1, and LIG3 Genes and Alzheimer's Disease Risk
Kwiatkowski, Dominik, Czarny, Piotr, Toma, Monika, Korycinska, Anna, Sowinska, Katarzyna, Galecki, Piotr, Bachurska, Agnieszka, Bielecka-Kowalska, Anna, Szemraj, Janusz, Maes, Michael, Sliwinski, Tomasz
Published in Neuropsychobiology (01.01.2016)
Published in Neuropsychobiology (01.01.2016)
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Journal Article
Clonal Medicine Targeting DNA Damage Response Eradicates AML
Toma, Monika, Karami, Adam, Nieborowska-Skorska, Margaret, Chitrala, Kumaraswamy, Valent, Peter, Skorski, Tomasz
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Clonal Targeting of DNA Damage Response Pathways Eradicates Myeloproliferative Neoplasms
Toma, Monika, Nieborowska-Skorska, Margaret, Karami, Adam, Pepek, Monika, Stoklosa, Tomasz, Skorski, Tomasz
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
RAD52 as a Potential Target for Synthetic Lethality-Based Anticancer Therapies
Toma, Monika, Sullivan-Reed, Katherine, Śliwiński, Tomasz, Skorski, Tomasz
Published in Cancers (14.10.2019)
Published in Cancers (14.10.2019)
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Journal Article
Divergent Functions of ERK2 Substrate Binding Modalities in Myeloproliferative Neoplasm
Truong, Billy, Toma, Monika, Zhang, Yong, Shinton, Susan, Li, Muheng, Hua, Xiang, Kappes, Dietmar, Shapiro, Paul, Skorski, Tomasz, Wiest, David L.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
The levels of 7,8-dihydrodeoxyguanosine (8-oxoG) and 8-oxoguanine DNA glycosylase 1 (OGG1) – A potential diagnostic biomarkers of Alzheimer's disease
Sliwinska, Agnieszka, Kwiatkowski, Dominik, Czarny, Piotr, Toma, Monika, Wigner, Paulina, Drzewoski, Jozef, Fabianowska-Majewska, Krystyna, Szemraj, Janusz, Maes, Michael, Galecki, Piotr, Sliwinski, Tomasz
Published in Journal of the neurological sciences (15.09.2016)
Published in Journal of the neurological sciences (15.09.2016)
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Journal Article
Induction of apoptosis by in vitro and in vivo plant extracts derived from Menyanthes trifoliata L. in human cancer cells
Kowalczyk, Tomasz, Sitarek, Przemysław, Skała, Ewa, Toma, Monika, Wielanek, Marzena, Pytel, Dariusz, Wieczfińska, Joanna, Szemraj, Janusz, Śliwiński, Tomasz
Published in Cytotechnology (Dordrecht) (01.02.2019)
Published in Cytotechnology (Dordrecht) (01.02.2019)
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Journal Article