Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers
Cantley, Jennifer, Ye, Xiaofen, Rousseau, Emma, Januario, Tom, Hamman, Brian D., Rose, Christopher M., Cheung, Tommy K., Hinkle, Trent, Soto, Leofal, Quinn, Connor, Harbin, Alicia, Bortolon, Elizabeth, Chen, Xin, Haskell, Roy, Lin, Eva, Yu, Shang-Fan, Del Rosario, Geoff, Chan, Emily, Dunlap, Debra, Koeppen, Hartmut, Martin, Scott, Merchant, Mark, Grimmer, Matt, Broccatelli, Fabio, Wang, Jing, Pizzano, Jennifer, Dragovich, Peter S., Berlin, Michael, Yauch, Robert L.
Published in Nature communications (10.11.2022)
Published in Nature communications (10.11.2022)
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In vivo Antitumor Activity of MEK and Phosphatidylinositol 3-Kinase Inhibitors in Basal-Like Breast Cancer Models
HOEFLICH, Klaus P, O'BRIEN, Carol, WEI ZHOU, BERRY, Leanne, MURRAY, Lesley, AMLER, Lukas, BELVIN, Marcia, FRIEDMAN, Lori S, LACKNER, Mark R, BOYD, Zachary, CAVET, Guy, GUERRERO, Steve, JUNG, Kenneth, JANUARIO, Tom, SAVAGE, Heidi, PUNNOOSE, Elizabeth, TRUONG, Tom
Published in Clinical cancer research (15.07.2009)
Published in Clinical cancer research (15.07.2009)
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Pharmacokinetic-Pharmacodynamic Analysis of Vismodegib in Preclinical Models of Mutational and Ligand-Dependent Hedgehog Pathway Activation
WONG, Harvey, ALICKE, Bruno, WEST, Kristina A, PACHECO, Patricia, LA, Hank, JANUARIO, Tom, YAUCH, Robert L, DE SAUVAGE, Frederic J, GOULD, Stephen E
Published in Clinical cancer research (15.07.2011)
Published in Clinical cancer research (15.07.2011)
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Journal Article
DNA Methylation Profiling Defines Clinically Relevant Biological Subsets of Non―Small Cell Lung Cancer
WALTER, Kim, HOLCOMB, Thomas, MODRUSAN, Zora, SESHAGIRI, Somasekar, HAMPTON, Garret M, AMLER, Lukas C, BOURGON, Richard, YAUCH, Robert L, SHAMES, David S, JANUARIO, Tom, PAN DU, EVANGELISTA, Marie, KARTHA, Nithya, INIGUEZ, Leonardo, SORIANO, Robert, HUW, Ling, STERN, Howard
Published in Clinical cancer research (15.04.2012)
Published in Clinical cancer research (15.04.2012)
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High heregulin expression is associated with activated HER3 and may define an actionable biomarker in patients with squamous cell carcinomas of the head and neck
Shames, David S, Carbon, Juliet, Walter, Kim, Jubb, Adrian M, Kozlowski, Cleopatra, Januario, Tom, Do, An, AnDo, Fu, Ling, Xiao, Yuanyuan, Raja, Rajiv, Jiang, Brittany, Malekafzali, Ashi, Stern, Howard, Settleman, Jeff, Wilson, Timothy R, Hampton, Garret M, Yauch, Robert L, Pirzkall, Andrea, Amler, Lukas C
Published in PloS one (28.02.2013)
Published in PloS one (28.02.2013)
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Discovery and development of DNA methylation-based biomarkers for lung cancer
Walter, Kimberly, Holcomb, Thomas, Januario, Tom, Yauch, Robert L, Du, Pan, Bourgon, Richard, Seshagiri, Somasekar, Amler, Lukas C, Hampton, Garret M, S Shames, David
Published in Epigenomics (01.02.2014)
Published in Epigenomics (01.02.2014)
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Correction: High Heregulin Expression Is Associated with Activated HER3 and May Define an Actionable Biomarker in Patients with Squamous Cell Carcinomas of the Head and Neck
Shames, David S., Carbon, Juliet, Walter, Kim, Jubb, Adrian M., Kozlowski, Cleopatra, Januario, Tom, Do, An, Fu, Ling, Xiao, Yuanyuan, Raja, Rajiv, Jiang, Brittany, Malekafzali, Ashi, Stern, Howard, Settleman, Jeff, Wilson, Timothy R., Hampton, Garret M., Yauch, Robert L., Pirzkall, Andrea, Amler, Lukas C.
Published in PloS one (18.06.2013)
Published in PloS one (18.06.2013)
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Smarca2 genetic ablation is phenotypically benign in a safety assessment of tamoxifen-inducible conditional knockout rats
Maher, Jonathan, Stagg, Nicola, Cain, Gary, Andaya, Roxanne, Katavolos, Paula, Gallardo-Chang, Fermin, Pham, Anna, Ye, Xiaofen, Januario, Tom, Alcantar, Tuija, Caothien, Roger, Roose-Girma, Merone, Zhang, Donglu, Li, Ruina, Chen, Shu, Yauch, Robert L.
Published in Toxicology and applied pharmacology (15.09.2023)
Published in Toxicology and applied pharmacology (15.09.2023)
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Abstract 5869: Characterization and therapeutic implications of SMARCA4 mutations in cancer
Fernando, Tharu M., Piskol, Robert, Bainer, Russell, Sokol, Ethan, Trabucco, Sally, Zhang, Qing, Trinh, Huong, Maund, Sophia, Kschonsak, Marc, Chaudhuri, Subhra, Januario, Tom, Modrusan, Zora, Yauch, Robert L.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Biomarker Analyses from a Placebo-Controlled Phase II Study Evaluating Erlotinib ± Onartuzumab in Advanced Non-Small Cell Lung Cancer: MET Expression Levels Are Predictive of Patient Benefit
KOEPPEN, Hartmut, WEI YU, LING FU, AN DO, PARAB, Vaishali, XIAOLING XIA, JANUARIO, Tom, LOUIE, Sharianne G, FILVAROFF, Ellen, SHAMES, David S, WISTUBA, Ignacio, LIPKIND, Marina, JIPING ZHA, HUANG, Jenny, LAZAROV, Mirella, RAMAKRISHNAN, Vanitha, AMLER, Lukas, PHAN, See-Chun, PATEL, Premal, PETERSON, Amy, YAUCH, Robert L, PANDITA, Ajay, PENUEL, Elicia, RANGELL, Linda, RAJA, Rajiv, MOHAN, Sankar, PATEL, Rajesh, DESAI, Rupal
Published in Clinical cancer research (01.09.2014)
Published in Clinical cancer research (01.09.2014)
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Biomarker Analyses from a Placebo-Controlled Phase II Study Evaluating Erlotinib plus or minus Onartuzumab in Advanced Non-Small Cell Lung Cancer: MET Expression Levels Are Predictive of Patient Benefit
Koeppen, Hartmut, Yu, Wei, Zha, Jiping, Pandita, Ajay, Penuel, Elicia, Rangell, Linda, Raja, Rajiv, Mohan, Sankar, Patel, Rajesh, Desai, Rupal, Fu, Ling, Do, An, Parab, Vaishali, Xia, Xiaoling, Januario, Tom, Louie, Sharianne G, Filvaroff, Ellen, Shames, David S, Wistuba, Ignacio, Lipkind, Marina, Huang, Jenny, Lazarov, Mirella, Ramakrishnan, Vanitha, Amler, Lukas, Phan, See-Chun, Patel, Premal, Peterson, Amy, Yauch, Robert L
Published in Clinical cancer research (01.09.2014)
Published in Clinical cancer research (01.09.2014)
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Abstract 1732: DNA methylation profiling defines clinically relevant biological subsets of non-small cell lung cancer
Walter, Kim, Holcomb, Thomas, Januario, Tom, Du, Pan, Hampton, Garret M., Amler, Lukas C., Yauch, Robert L., Bourgon, Richard, Shames, David S.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Identification of a Diagnostic Gene Signature for SGN-40, Anti-CD40 Monoclonal Antibody, in Pre-Clinical NHL Models and the Role of FAS in SGN-40 Mediated Apoptosis
Shi, Xiaoyan, Burington, Bart, Januario, Tom, Lau, Jeffrey T, Yu, Shang-Fan, Ebens, Allen, Dornan, David
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Abstract LB-221: Differential aberrant DNA methylation predicts for Tarceva response in NSCLC
Shames, David S., Januario, Tom, Holcomb, Thomas, Soriano, Robert, Wu, Thomas, Modrusan, Zora, Seshagiri, Somasekar, Egan, Brian, Hampton, Garret M., Amler, Lukas C., Yauch, Robert L.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Antibody-Drug Conjugates with Uncleavable Linkers for the Treatment of Non-Hodgkin Lymphoma
Polson, Andrew G., Clark, Suzanna, Du, Changchun, Eaton, Dan, Elkins, Kristi, Fuji, Reina N., Ann, Mary, Gray, Alane, Januario, Tom, Koeppen, Hartmut, Lau, Jeffery, Leach, Will, McDorman, Elena, McKeever, Kathleen, Prabhu, Saileta, Scales, Suzie J., Slaga, Dionysos, Spencer, Susan, Williams, Marna, Xie, David, Yu, Shang-Fan, Zheng, Bing, Ebens, Allen
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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Correction: High Heregulin Expression Is Associated with Activated HER3 and May Define an Actionable Biomarker in Patients with Squamous Cell Carcinomas of the Head and Neck
David S. Shames, Juliet Carbon, Kim Walter, Adrian M. Jubb, Cleopatra Kozlowski, Tom Januario, An Do, Ling Fu, Yuanyuan Xiao, Rajiv Raja, Brittany Jiang, Ashi Malekafzali, Howard Stern, Jeff Settleman, Timothy R. Wilson, Garret M. Hampton, Robert L. Yauch, Andrea Pirzkall, Lukas C. Amler
Published in PloS one (01.01.2013)
Published in PloS one (01.01.2013)
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Topical application of AHAs releases interleukin-1α from stratum corneum
Januario, Tom, Bartolone, John, Santhanam, Uma
Published in Journal of dermatological science (01.03.1998)
Published in Journal of dermatological science (01.03.1998)
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