Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1
Xu, Wei, Edwards, Megan R., Borek, Dominika M., Feagins, Alicia R., Mittal, Anuradha, Alinger, Joshua B., Berry, Kayla N., Yen, Benjamin, Hamilton, Jennifer, Brett, Tom J., Pappu, Rohit V., Leung, Daisy W., Basler, Christopher F., Amarasinghe, Gaya K.
Published in Cell host & microbe (13.08.2014)
Published in Cell host & microbe (13.08.2014)
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TREM-2 promotes macrophage survival and lung disease after respiratory viral infection
Wu, Kangyun, Byers, Derek E, Jin, Xiaohua, Agapov, Eugene, Alexander-Brett, Jennifer, Patel, Anand C, Cella, Marina, Gilfilan, Susan, Colonna, Marco, Kober, Daniel L, Brett, Tom J, Holtzman, Michael J
Published in The Journal of experimental medicine (04.05.2015)
Published in The Journal of experimental medicine (04.05.2015)
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Modulation of TMEM16A channel activity by the von Willebrand factor type A (VWA) domain of the calcium-activated chloride channel regulator 1 (CLCA1)
Sala-Rabanal, Monica, Yurtsever, Zeynep, Berry, Kayla N., Nichols, Colin G., Brett, Tom J.
Published in The Journal of biological chemistry (02.06.2017)
Published in The Journal of biological chemistry (02.06.2017)
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PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection
Zhang, Yong, Mao, Dailing, Roswit, William T, Jin, Xiaohua, Patel, Anand C, Patel, Dhara A, Agapov, Eugene, Wang, Zhepeng, Tidwell, Rose M, Atkinson, Jeffrey J, Huang, Guangming, McCarthy, Ronald, Yu, Jinsheng, Yun, Nadezhda E, Paessler, Slobodan, Lawson, T Glen, Omattage, Natalie S, Brett, Tom J, Holtzman, Michael J
Published in Nature immunology (01.12.2015)
Published in Nature immunology (01.12.2015)
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Screening for familial hypercholesterolaemia in primary care: Time for general practice to play its part
Brett, Tom, Qureshi, Nadeem, Gidding, Samuel, Watts, Gerald F.
Published in Atherosclerosis (01.10.2018)
Published in Atherosclerosis (01.10.2018)
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Secreted CLCA1 modulates TMEM16A to activate Ca(2+)-dependent chloride currents in human cells
Sala-Rabanal, Monica, Yurtsever, Zeynep, Nichols, Colin G, Brett, Tom J
Published in eLife (17.03.2015)
Published in eLife (17.03.2015)
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TREM2 on microglia cell surface binds to and forms functional binary complexes with heparan sulfate modified with 6-O-sulfation and iduronic acid
McMillan, Ilayda Ozsan, Liang, Li, Su, Guowei, Song, Xuehong, Drago, Kelly, Yang, Hua, Alvarez, Claudia, Sood, Amika, Gibson, James, Woods, Robert J., Wang, Chunyu, Liu, Jian, Zhang, Fuming, Brett, Tom J., Wang, Lianchun
Published in The Journal of biological chemistry (01.09.2024)
Published in The Journal of biological chemistry (01.09.2024)
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IL-13-induced airway mucus production is attenuated by MAPK13 inhibition
Alevy, Yael G, Patel, Anand C, Romero, Arthur G, Patel, Dhara A, Tucker, Jennifer, Roswit, William T, Miller, Chantel A, Heier, Richard F, Byers, Derek E, Brett, Tom J, Holtzman, Michael J
Published in The Journal of clinical investigation (01.12.2012)
Published in The Journal of clinical investigation (01.12.2012)
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Secreted CLCA1 modulates TMEM16A to activate Ca2+-dependent chloride currents in human cells
Sala-Rabanal, Monica, Yurtsever, Zeynep, Nichols, Colin G, Brett, Tom J
Published in eLife (17.03.2015)
Published in eLife (17.03.2015)
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BST-2/tetherin: Structural biology, viral antagonism, and immunobiology of a potent host antiviral factor
Swiecki, Melissa, Omattage, Natalie S., Brett, Tom J.
Published in Molecular immunology (01.06.2013)
Published in Molecular immunology (01.06.2013)
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Modulation of TMEM16B channel activity by the calcium-activated chloride channel regulator 4 (CLCA4) in human cells
Sala-Rabanal, Monica, Yurtsever, Zeynep, Berry, Kayla N., McClenaghan, Conor, Foy, Alyssa J., Hanson, Alex, Steinberg, Deborah F., Greven, Jessica A., Kluender, Colin E., Alexander-Brett, Jennifer M., Nichols, Colin G., Brett, Tom J.
Published in The Journal of biological chemistry (01.07.2024)
Published in The Journal of biological chemistry (01.07.2024)
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Lrp1 is a host entry factor for Rift Valley fever virus
Ganaie, Safder S., Schwarz, Madeline M., McMillen, Cynthia M., Price, David A., Feng, Annie X., Albe, Joseph R., Wang, Wenjie, Miersch, Shane, Orvedahl, Anthony, Cole, Aidan R., Sentmanat, Monica F., Mishra, Nawneet, Boyles, Devin A., Koenig, Zachary T., Kujawa, Michael R., Demers, Matthew A., Hoehl, Ryan M., Moyle, Austin B., Wagner, Nicole D., Stubbs, Sarah H., Cardarelli, Lia, Teyra, Joan, McElroy, Anita, Gross, Michael L., Whelan, Sean P.J., Doench, John, Cui, Xiaoxia, Brett, Tom J., Sidhu, Sachdev S., Virgin, Herbert W., Egawa, Takeshi, Leung, Daisy W., Amarasinghe, Gaya K., Hartman, Amy L.
Published in Cell (30.09.2021)
Published in Cell (30.09.2021)
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Functional insights from biophysical study of TREM2 interactions with apoE and Aβ1‐42
Kober, Daniel L., Stuchell‐Brereton, Melissa D., Kluender, Colin E., Dean, Hunter B., Strickland, Michael R., Steinberg, Deborah F., Nelson, Samantha S., Baban, Berevan, Holtzman, David M., Frieden, Carl, Alexander‐Brett, Jennifer, Roberson, Erik D., Song, Yuhua, Brett, Tom J.
Published in Alzheimer's & dementia (01.03.2021)
Published in Alzheimer's & dementia (01.03.2021)
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The role of CLCA proteins in inflammatory airway disease
Patel, Anand C, Brett, Tom J, Holtzman, Michael J
Published in Annual review of physiology (01.01.2009)
Published in Annual review of physiology (01.01.2009)
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