Fructose and sugar: A major mediator of non-alcoholic fatty liver disease
Jensen, Thomas, Abdelmalek, Manal F., Sullivan, Shelby, Nadeau, Kristen J., Green, Melanie, Roncal, Carlos, Nakagawa, Takahiko, Kuwabara, Masanari, Sato, Yuka, Kang, Duk-Hee, Tolan, Dean R., Sanchez-Lozada, Laura G., Rosen, Hugo R., Lanaspa, Miguel A., Diehl, Anna Mae, Johnson, Richard J.
Published in Journal of hepatology (01.05.2018)
Published in Journal of hepatology (01.05.2018)
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Journal Article
Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton
Hu, Hai, Juvekar, Ashish, Lyssiotis, Costas A., Lien, Evan C., Albeck, John G., Oh, Doogie, Varma, Gopal, Hung, Yin Pun, Ullas, Soumya, Lauring, Josh, Seth, Pankaj, Lundquist, Mark R., Tolan, Dean R., Grant, Aaron K., Needleman, Daniel J., Asara, John M., Cantley, Lewis C., Wulf, Gerburg M.
Published in Cell (28.01.2016)
Published in Cell (28.01.2016)
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Journal Article
Uric Acid as a Cause of the Metabolic Syndrome
King, Christopher, Lanaspa, Miguel A, Jensen, Thomas, Tolan, Dean R, Sánchez-Lozada, L Gabriela, Johnson, Richard J
Published in Contributions to nephrology (01.01.2018)
Published in Contributions to nephrology (01.01.2018)
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Journal Article
Climate Change and the Kidney
Johnson, Richard J., Sánchez-Lozada, Laura G., Newman, Lee S., Lanaspa, Miguel A., Diaz, Henry F., Lemery, Jay, Rodriguez-Iturbe, Bernardo, Tolan, Dean R., Butler-Dawson, Jaime, Sato, Yuka, Garcia, Gabriela, Hernando, Ana Andres, Roncal-Jimenez, Carlos A.
Published in Annals of nutrition and metabolism (01.01.2019)
Published in Annals of nutrition and metabolism (01.01.2019)
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Journal Article
Increase of core temperature affected the progression of kidney injury by repeated heat stress exposure
Sato, Yuka, Roncal-Jimenez, Carlos A, Andres-Hernando, Ana, Jensen, Thomas, Tolan, Dean R, Sanchez-Lozada, Laura G, Newman, Lee S, Butler-Dawson, Jaime, Sorensen, Cecilia, Glaser, Jason, Miyazaki, Makoto, Diaz, Henry F, Ishimoto, Takuji, Kosugi, Tomoki, Maruyama, Shoichi, Garcia, Gabriela E, Lanaspa, Miguel A, Johnson, Richard J
Published in American journal of physiology. Renal physiology (01.11.2019)
Published in American journal of physiology. Renal physiology (01.11.2019)
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Journal Article
Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans
Oppelt, Sarah A., Sennott, Erin M., Tolan, Dean R.
Published in Molecular genetics and metabolism (01.03.2015)
Published in Molecular genetics and metabolism (01.03.2015)
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Journal Article
Fructose contributes to the Warburg effect for cancer growth
Nakagawa, Takahiko, Lanaspa, Miguel A, Millan, Inigo San, Fini, Mehdi, Rivard, Christopher J, Sanchez-Lozada, Laura G, Andres-Hernando, Ana, Tolan, Dean R, Johnson, Richard J
Published in Cancer & metabolism (10.07.2020)
Published in Cancer & metabolism (10.07.2020)
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Journal Article
Endogenous Fructose Production and Metabolism Drive Metabolic Dysregulation and Liver Disease in Mice with Hereditary Fructose Intolerance
Andres-Hernando, Ana, Orlicky, David J, Kuwabara, Masanari, Cicerchi, Christina, Pedler, Michelle, Petrash, Mark J, Johnson, Richard J, Tolan, Dean R, Lanaspa, Miguel A
Published in Nutrients (01.10.2023)
Published in Nutrients (01.10.2023)
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Journal Article
Role of fructose and fructokinase in acute dehydration-induced vasopressin gene expression and secretion in mice
Song 宋志林, Zhilin, Roncal-Jimenez, Carlos A, Lanaspa-Garcia, Miguel A, Oppelt, Sarah A, Kuwabara, Masanari, Jensen, Thomas, Milagres, Tamara, Andres-Hernando, Ana, Ishimoto, Takuji, Garcia, Gabriela E, Johnson, Ginger, MacLean, Paul S, Sanchez-Lozada, Laura-Gabriela, Tolan, Dean R, Johnson, Richard J
Published in Journal of neurophysiology (01.02.2017)
Published in Journal of neurophysiology (01.02.2017)
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Journal Article
Fructose might be a clue to the origin of preeclampsia insights from nature and evolution
Nakagawa, Takahiko, Ana Andres-Hernando, Kosugi, Tomoki, Sanchez-Lozada, Laura G, Stenvinkel, Peter, Kublickiene, Karolina, Ananth Karumanchi, S, Kang, Duk-Hee, Kojima, Hideto, Rodriguez-Iturbe, Bernardo, Tolan, Dean R, Lanaspa, Miguel A, Johnson, Richard J
Published in Hypertension research (01.03.2023)
Published in Hypertension research (01.03.2023)
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Journal Article
Hepatic glucokinase regulatory protein and carbohydrate response element binding protein attenuation reduce de novo lipogenesis but do not mitigate intrahepatic triglyceride accumulation in Aldob deficiency
Buziau, Amée M., Oosterveer, Maaike H., Wouters, Kristiaan, Bos, Trijnie, Tolan, Dean R., Agius, Loranne, Ford, Brian E., Cassiman, David, Stehouwer, Coen D.A., Schalkwijk, Casper G., Brouwers, Martijn C.G.J.
Published in Molecular metabolism (Germany) (01.09.2024)
Published in Molecular metabolism (Germany) (01.09.2024)
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Journal Article
Activation of AMPD2 drives metabolic dysregulation and liver disease in mice with hereditary fructose intolerance
Andres-Hernando, Ana, Orlicky, David J, Kuwabara, Masanari, Fini, Mehdi A, Tolan, Dean R, Johnson, Richard J, Lanaspa, Miguel A
Published in Communications biology (11.07.2024)
Published in Communications biology (11.07.2024)
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Journal Article
Michaelis-like complex of mouse ketohexokinase isoform C
Gasper, William C, Gardner, Sarah, Ross, Adam, Oppelt, Sarah A, Allen, Karen N, Tolan, Dean R
Published in Acta crystallographica. Section D, Biological crystallography. (01.06.2024)
Published in Acta crystallographica. Section D, Biological crystallography. (01.06.2024)
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Journal Article
Could Alzheimer’s disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?
Johnson, Richard J., Tolan, Dean R., Bredesen, Dale, Nagel, Maria, Sánchez-Lozada, Laura G., Fini, Mehdi, Burtis, Scott, Lanaspa, Miguel A., Perlmutter, David
Published in The American journal of clinical nutrition (01.03.2023)
Published in The American journal of clinical nutrition (01.03.2023)
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Journal Article
Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease
Buziau, Amée M., Schalkwijk, Casper G., Stehouwer, Coen D.A., Tolan, Dean R., Brouwers, Martijn C.G.J.
Published in Cellular and molecular life sciences : CMLS (01.05.2020)
Published in Cellular and molecular life sciences : CMLS (01.05.2020)
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