The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment
Hardaker, Elizabeth L., Sanseviero, Emilio, Karmokar, Ankur, Taylor, Devon, Milo, Marta, Michaloglou, Chrysis, Hughes, Adina, Mai, Mimi, King, Matthew, Solanki, Anisha, Magiera, Lukasz, Miragaia, Ricardo, Kar, Gozde, Standifer, Nathan, Surace, Michael, Gill, Shaan, Peter, Alison, Talbot, Sara, Tohumeken, Sehmus, Fryer, Henderson, Mostafa, Ali, Mulgrew, Kathy, Lam, Carolyn, Hoffmann, Scott, Sutton, Daniel, Carnevalli, Larissa, Calero-Nieto, Fernando J., Jones, Gemma N., Pierce, Andrew J., Wilson, Zena, Campbell, David, Nyoni, Lynet, Martins, Carla P., Baker, Tamara, Serrano de Almeida, Gilberto, Ramlaoui, Zainab, Bidar, Abdel, Phillips, Benjamin, Boland, Joseph, Iyer, Sonia, Barrett, J. Carl, Loembé, Arsene-Bienvenu, Fuchs, Serge Y., Duvvuri, Umamaheswar, Lou, Pei-Jen, Nance, Melonie A., Gomez Roca, Carlos Alberto, Cadogan, Elaine, Critichlow, Susan E., Fawell, Steven, Cobbold, Mark, Dean, Emma, Valge-Archer, Viia, Lau, Alan, Gabrilovich, Dmitry I., Barry, Simon T.
Published in Nature communications (24.02.2024)
Published in Nature communications (24.02.2024)
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CD33/CD3-bispecific T-cell engaging (BiTE®) antibody construct targets monocytic AML myeloid-derived suppressor cells
Jitschin, Regina, Saul, Domenica, Braun, Martina, Tohumeken, Sehmus, Völkl, Simon, Kischel, Roman, Lutteropp, Michael, Dos Santos, Cedric, Mackensen, Andreas, Mougiakakos, Dimitrios
Published in Journal for immunotherapy of cancer (05.11.2018)
Published in Journal for immunotherapy of cancer (05.11.2018)
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957 The ATR-inhibitor ceralasertib modulates the tumor microenvironment and improves the effect of anti-PDL1 by activating type I IFN pathway
Sanseviero, Emilio, Taylor, Devon, Tohumeken, Sehmus, Mai, Mimi, Mostafa, Ali, Milo, Marta, Mulgrew, Kathy, Barry, Simon, Fuchs, Serge, Cobbold, Mark, Gabrilovich, Dmitry
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Palmitoylated Proteins on AML-Derived Extracellular Vesicles Promote Myeloid-Derived Suppressor Cell Differentiation via TLR2/Akt/mTOR Signaling
Tohumeken, Sehmus, Baur, Rebecca, Böttcher, Martin, Stoll, Andrej, Loschinski, Romy, Panagiotidis, Konstantinos, Braun, Martina, Saul, Domenica, Völkl, Simon, Baur, Andreas S, Bruns, Heiko, Mackensen, Andreas, Jitschin, Regina, Mougiakakos, Dimitrios
Published in Cancer research (Chicago, Ill.) (01.09.2020)
Published in Cancer research (Chicago, Ill.) (01.09.2020)
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Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound
Yoo, Seung-Wan, Waheed, Abdul A, Deme, Pragney, Tohumeken, Sehmus, Rais, Rana, Smith, Matthew D, DeMarino, Catherine, Calabresi, Peter A, Kashanchi, Fatah, Freed, Eric O, Slusher, Barbara S, Haughey, Norman J
Published in Proceedings of the National Academy of Sciences - PNAS (11.07.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (11.07.2023)
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Biotin Functionalized Self-Assembled Peptide Nanofiber as an Adjuvant for Immunomodulatory Response
Demircan, Muhammed Burak, Tohumeken, Sehmus, Gunduz, Nuray, Khalily, Mohammad Aref, Tekinay, Turgay, Guler, Mustafa O, Tekinay, Ayse B
Published in Biotechnology journal (01.12.2020)
Published in Biotechnology journal (01.12.2020)
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CD33/CD3-Bispecific T-Cell Engaging (BiTE®) Antibody Constructs Efficiently Target Monocytic CD14+ hla-DRlow IDO+ aml-MDSCs
Mougiakakos, Dimitrios, Saul, Domenica, Braun, Martina, Tohumeken, Sehmus, Kischel, Roman, Michael, Lutteropp, Dos Santos, Cedric E., Jitschin, Regina, Mackensen, Andreas
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Virus-like nanostructures for tuning immune response
Mammadov, Rashad, Cinar, Goksu, Gunduz, Nuray, Goktas, Melis, Kayhan, Handan, Tohumeken, Sehmus, Topal, Ahmet E., Orujalipoor, Ilghar, Delibasi, Tuncay, Dana, Aykutlu, Ide, Semra, Tekinay, Ayse B., Guler, Mustafa O.
Published in Scientific reports (18.11.2015)
Published in Scientific reports (18.11.2015)
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Diabetic wound regeneration using heparin-mimetic peptide amphiphile gel in db/db miceElectronic supplementary information (ESI) available. See DOI: 10.1039/c7bm00251c
Senturk, Berna, Demircan, Burak M, Ozkan, Alper D, Tohumeken, Sehmus, Delibasi, Tuncay, Guler, Mustafa O, Tekinay, Ayse B
Year of Publication 27.06.2017
Year of Publication 27.06.2017
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