DJ‐927, a novel oral taxane, overcomes P‐glycoprotein‐mediated multidrug resistance in vitro and in vivo
Shionoya, Motoko, Jimbo, Takeshi, Kitagawa, Mayumi, Soga, Tsunehiko, Tohgo, Akiko
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Published in Cancer science (01.05.2003)
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Circumvention of Breast Cancer Resistance Protein (BCRP)-mediated Resistance to Camptothecins in Vitro Using Non-Substrate Drugs or the BCRP Inhibitor GF120918
MALIEPAARD, Marc, VAN GASTELEN, Margot A, TOHGO, Akiko, HAUSHEER, Frederick H, VAN WAARDENBURG, Robert C. A. M, DE JONG, Laurina A, PLUIM, Dick, BEIJNEN, Jos H, SCHELLENS, Jan H. M
Published in Clinical cancer research (01.04.2001)
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Published in Clinical cancer research (01.04.2001)
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DX‐8951F, a water‐soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN‐38‐resistant variant
Joto, Noriko, Ishii, Mineko, Minami, Megumi, Kuga, Hiroshi, Mitsui, Ikuo, Tohgo, Akiko
Published in International journal of cancer (07.08.1997)
Published in International journal of cancer (07.08.1997)
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Growth inhibitory effect of a new camptothecin analog, DX-8951f, on various drug-resistant sublines including BCRP-mediated camptothecin derivative-resistant variants derived from the human lung cancer cell line PC-6
Ishii, M, Iwahana, M, Mitsui, I, Minami, M, Imagawa, S, Tohgo, A, Ejima, A
Published in Anti-cancer drugs (01.06.2000)
Published in Anti-cancer drugs (01.06.2000)
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Antitumor Effect of DX‐8951, a Novel Camptothecin Analog, on Human Pancreatic Tumor Cells and Their CPT‐11‐resistant Variants Cultured in vitro and Xenografted into Nude Mice
Takiguchi, Soichi, Kumazawa, Eiji, Shimazoe, Takao, Tohgo, Akiko, Kono, Akira
Published in Cancer science (01.08.1997)
Published in Cancer science (01.08.1997)
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Efficacy of camptothecin analog DX-8951f (exatecan mesylate) on human pancreatic cancer in an orthotopic metastatic model
SUN, Fang-Xian, TOHGO, Akiko, BOUVET, Michael, YAGI, Shigeo, NASSIRPOUR, Rounak, MOOSSA, Abdoul R, HOFFMAN, Robert M
Published in Cancer research (Chicago, Ill.) (2003)
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Published in Cancer research (Chicago, Ill.) (2003)
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Synthesis and Antitumor Activity of N-Acetylmuramyl-L-alanyl-D-isoglutamine 6-Phosphate and Its Lipophilic Derivatives
Imoto, Masahiro, Kageyama, Shigeki, Kusumoto, Shoichi, Kohno, Morihiro, Matsumoto, Kensuke, Hashimoto, Shinjiro, Tohgo, Akiko, Shiba, Tetsuo
Published in Bulletin of the Chemical Society of Japan (01.10.1986)
Published in Bulletin of the Chemical Society of Japan (01.10.1986)
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The activity profile of the hexacyclic camptothecin derivative DX-8951f in experimental human colon cancer and ovarian cancer
van Hattum, Annemarie H, Pinedo, Herbert M, Schlüper, Hennie M.M, Erkelens, Caroline A.M, Tohgo, Akiko, Boven, Epie
Published in Biochemical pharmacology (15.10.2002)
Published in Biochemical pharmacology (15.10.2002)
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Anticancer drugs that induce cancer-associated cachectic syndromes
Tohgo, Akiko, Kumazawa, Eiji, Akahane, Kouichi, Asakawa, Akihiro, Inui, Akio
Published in Expert review of anticancer therapy (01.02.2002)
Published in Expert review of anticancer therapy (01.02.2002)
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Antitumor activity of new combination chemotherapy with irinotecan hydrochloride and nedaplatin against human cervical cancer cell lines
Yamamoto, Kaichiro, Iwahana, Michio, Kumazawa, Eiji, Kakihata, Koji, Abe, Kunio, Hirano, Fuyumi, Tohgo, Akiko, Hoshiai, Hiroshi, Noda, Kiichiro
Published in Oncology reports (01.05.2003)
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Published in Oncology reports (01.05.2003)
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EFFECTS OF HUMAN FIBROBLAST INTERFERON ON HUMAN GLIOMAS TRANSPLANTED INTO NUDE MICE
TANAKA, Noriko, NAGAO, Shin'ichi, TOHGO, Akiko, SEKIGUCHI, Fujio, KOHNO, Morihiro, OGAWA, Hidemasa, MATSUI, Takane, MATSUTANI, Masao
Published in GANN Japanese Journal of Cancer Research (1983)
Published in GANN Japanese Journal of Cancer Research (1983)
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Comparison of DX-8951f and topotecan effects on tumor colony formation from freshly explanted adult and pediatric human tumor cells
Lawrence, R A, Izbicka, E, De Jager, R L, Tohgo, A, Clark, G M, Weitman, S D, Rowinsky, E K, Von Hoff, D D
Published in Anti-cancer drugs (01.08.1999)
Published in Anti-cancer drugs (01.08.1999)
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Production of tumor necrosis factor induced by synthetic low-toxicity lipid a analog, DT-5461a, is mediated by LPS receptor sites and tyrosine kinase—MAP kinase signaling pathway in murine macrophages
Joto, Noriko, Akimoto, Toshihiko, Someya, Kazuhiko, Tohgo, Akiko
Published in Cellular immunology (1995)
Published in Cellular immunology (1995)
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Significant antitumor effect of a synthetic lipid A analogue, DT-5461, on murine syngeneic tumor models
KUMAZAWA, E, TOHGO, A, SOGA, T, KUSAMA, T, OSADA, Y
Published in Cancer Immunology Immunotherapy (01.09.1992)
Published in Cancer Immunology Immunotherapy (01.09.1992)
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