β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor Stimulation
Tohgo, Akira, Pierce, Kristen L., Choy, Eric W., Lefkowitz, Robert J., Luttrell, Louis M.
Published in The Journal of biological chemistry (15.03.2002)
Published in The Journal of biological chemistry (15.03.2002)
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Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP
Takasawa, S, Tohgo, A, Noguchi, N, Koguma, T, Nata, K, Sugimoto, T, Yonekura, H, Okamoto, H
Published in The Journal of biological chemistry (15.12.1993)
Published in The Journal of biological chemistry (15.12.1993)
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A missense mutation in the CD38 gene, a novel factor for insulin secretion : association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro
YAGUI, K, SHIMADA, F, OKAMOTO, H, MAKINO, H, SAITO, Y, KANATSUKA, A, MIMURA, M, HASHIMOTO, N, SUZUKI, Y, TOKUYAMA, Y, NATA, K, TOHGO, A, IKEHATA, F, TAKASAWA, S
Published in Diabetologia (01.09.1998)
Published in Diabetologia (01.09.1998)
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Essential cysteine residues for cyclic ADP-ribose synthesis and hydrolysis by CD38
Tohgo, A, Takasawa, S, Noguchi, N, Koguma, T, Nata, K, Sugimoto, T, Furuya, Y, Yonekura, H, Okamoto, H
Published in The Journal of biological chemistry (18.11.1994)
Published in The Journal of biological chemistry (18.11.1994)
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Assignment of CD38, the gene encoding human leukocyte antigen CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase), to chromosome 4p15
Nakagawara, K, Mori, M, Takasawa, S, Nata, K, Takamura, T, Berlova, A, Tohgo, A, Karasawa, T, Yonekura, H, Takeuchi, T
Published in Cytogenetics and cell genetics (01.01.1995)
Published in Cytogenetics and cell genetics (01.01.1995)
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DNER acts as a neuron-specific Notch ligand during Bergmann glial development
Kengaku, Mineko, Eiraku, Mototsugu, Tohgo, Akira, Ono, Katsuhiko, Kaneko, Megumi, Fujishima, Kazuto, Hirano, Tomoo
Published in Nature neuroscience (01.07.2005)
Published in Nature neuroscience (01.07.2005)
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The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation
Tohgo, Akira, Choy, Eric W, Gesty-Palmer, Diane, Pierce, Kristen L, Laporte, Stephane, Oakley, Robert H, Caron, Marc G, Lefkowitz, Robert J, Luttrell, Louis M
Published in The Journal of biological chemistry (21.02.2003)
Published in The Journal of biological chemistry (21.02.2003)
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Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding
Pierce, K L, Tohgo, A, Ahn, S, Field, M E, Luttrell, L M, Lefkowitz, R J
Published in The Journal of biological chemistry (22.06.2001)
Published in The Journal of biological chemistry (22.06.2001)
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Circumvention of Breast Cancer Resistance Protein (BCRP)-mediated Resistance to Camptothecins in Vitro Using Non-Substrate Drugs or the BCRP Inhibitor GF120918
MALIEPAARD, Marc, VAN GASTELEN, Margot A, TOHGO, Akiko, HAUSHEER, Frederick H, VAN WAARDENBURG, Robert C. A. M, DE JONG, Laurina A, PLUIM, Dick, BEIJNEN, Jos H, SCHELLENS, Jan H. M
Published in Clinical cancer research (01.04.2001)
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Published in Clinical cancer research (01.04.2001)
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Impaired cerebellar functions in mutant mice lacking DNER
Tohgo, Akira, Eiraku, Mototsugu, Miyazaki, Taisuke, Miura, Eriko, Kawaguchi, Shin-ya, Nishi, Miyuki, Watanabe, Masahiko, Hirano, Tomoo, Kengaku, Mineko, Takeshima, Hiroshi
Published in Molecular and cellular neuroscience (01.02.2006)
Published in Molecular and cellular neuroscience (01.02.2006)
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DJ‐927, a novel oral taxane, overcomes P‐glycoprotein‐mediated multidrug resistance in vitro and in vivo
Shionoya, Motoko, Jimbo, Takeshi, Kitagawa, Mayumi, Soga, Tsunehiko, Tohgo, Akiko
Published in Cancer science (01.05.2003)
Published in Cancer science (01.05.2003)
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Efficacy of camptothecin analog DX-8951f (exatecan mesylate) on human pancreatic cancer in an orthotopic metastatic model
SUN, Fang-Xian, TOHGO, Akiko, BOUVET, Michael, YAGI, Shigeo, NASSIRPOUR, Rounak, MOOSSA, Abdoul R, HOFFMAN, Robert M
Published in Cancer research (Chicago, Ill.) (2003)
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Published in Cancer research (Chicago, Ill.) (2003)
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Cyclic ADP-ribose Binds to FK506-binding Protein 12.6 to Release Ca2+ from Islet Microsomes
Noguchi, Naoya, Takasawa, Shin, Nata, Koji, Tohgo, Akira, Kato, Ichiro, Ikehata, Fumiko, Yonekura, Hideto, Okamoto, Hiroshi
Published in The Journal of biological chemistry (07.02.1997)
Published in The Journal of biological chemistry (07.02.1997)
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