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Study of Tofacitinib in Refractory Dermatomyositis: An Open‐Label Pilot Study of Ten Patients
Paik, Julie J., Casciola‐Rosen, Livia, Shin, Joseph Yusup, Albayda, Jemima, Tiniakou, Eleni, Leung, Doris G., Gutierrez‐Alamillo, Laura, Perin, Jamie, Florea, Liliana, Antonescu, Corina, Leung, Sherry G., Purwin, Grazyna, Koenig, Andrew, Christopher‐Stine, Lisa
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2021)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2021)
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Comparison of baricitinib, upadacitinib, and tofacitinib mediated regulation of cytokine signaling in human leukocyte subpopulations
McInnes, Iain B., Byers, Nicole L., Higgs, Richard E., Lee, Jonathan, Macias, William L., Ortmann, Robert A., Rocha, Guilherme, Rooney, Terence P., Wehrman, Thomas, Zhang, Xin, Zuckerman, Steven H., Taylor, Peter C.
Published in Arthritis research & therapy (02.08.2019)
Published in Arthritis research & therapy (02.08.2019)
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Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus
Hasni, Sarfaraz A., Gupta, Sarthak, Davis, Michael, Poncio, Elaine, Temesgen-Oyelakin, Yenealem, Carlucci, Philip M., Wang, Xinghao, Naqi, Mohammad, Playford, Martin P., Goel, Rishi R., Li, Xiaobai, Biehl, Ann J., Ochoa-Navas, Isabel, Manna, Zerai, Shi, Yinghui, Thomas, Donald, Chen, Jinguo, Biancotto, Angélique, Apps, Richard, Cheung, Foo, Kotliarov, Yuri, Babyak, Ashley L., Zhou, Huizhi, Shi, Rongye, Stagliano, Katie, Tsai, Wanxia Li, Vian, Laura, Gazaniga, Nathalia, Giudice, Valentina, Lu, Shajia, Brooks, Stephen R., MacKay, Meggan, Gregersen, Peter, Mehta, Nehal N., Remaley, Alan T., Diamond, Betty, O’Shea, John J., Gadina, Massimo, Kaplan, Mariana J.
Published in Nature communications (07.06.2021)
Published in Nature communications (07.06.2021)
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The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
Dowty, Martin E., Lin, Jinyan, Ryder, Tim F., Wang, Weiwei, Walker, Gregory S., Vaz, Alfin, Chan, Gary L., Krishnaswami, Sriram, Prakash, Chandra
Published in Drug metabolism and disposition (01.04.2014)
Published in Drug metabolism and disposition (01.04.2014)
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A randomized, crossover, phase I clinical study to evaluate bioequivalence and safety of tofacitinib and Xeljanz® in Chinese healthy subjects
Xu, Zhongnan, Wang, Yanli, Liu, Zhengzhi, Zhang, Renjie, Zhou, Yannan, Yu, Jing, Lan, Jing, Liang, Wenzhong, Liu, Guangwen, Qu, Xinyao, Chen, Jiahui, Su, Zhengjie, Yu, Shuang, Cheng, Yang, Wang, Wanhua, Ren, Qing, Deng, Qiaohuan, Zhao, Yicheng, Yang, Haimiao
Published in International immunopharmacology (01.08.2022)
Published in International immunopharmacology (01.08.2022)
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Virtual Bioequivalence Assessment of Tofacitinib Once Daily Modified Release Dosage Form in Pediatric Subjects
Sagawa, Kazuko, Purohit, Vivek, Le, Vu, Hsu, Hao-Jui, Dowty, Martin E., Tse, Susanna, Chang, Cheng
Published in The AAPS journal (01.04.2025)
Published in The AAPS journal (01.04.2025)
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Tofacitinib Therapy in Children and Young Adults With Pediatric-onset Medically Refractory Inflammatory Bowel Disease
Moore, Hillary, Dubes, Lucie, Fusillo, Steven, Baldassano, Robert, Stein, Ronen
Published in Journal of pediatric gastroenterology and nutrition (01.09.2021)
Published in Journal of pediatric gastroenterology and nutrition (01.09.2021)
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An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis
Jabbari, A., Sansaricq, F., Cerise, J., Chen, J.C., Bitterman, A., Ulerio, G., Borbon, J., Clynes, R., Christiano, A.M., Mackay-Wiggan, J.
Published in Journal of investigative dermatology (01.07.2018)
Published in Journal of investigative dermatology (01.07.2018)
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Tuberculosis and other opportunistic infections in tofacitinib-treated patients with rheumatoid arthritis
Winthrop, K L, Park, S-H, Gul, A, Cardiel, M H, Gomez-Reino, J J, Tanaka, Y, Kwok, K, Lukic, T, Mortensen, E, Ponce de Leon, D, Riese, R, Valdez, H
Published in Annals of the rheumatic diseases (01.06.2016)
Published in Annals of the rheumatic diseases (01.06.2016)
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Tofacitinib: The First Janus Kinase (JAK) inhibitor for the treatment of rheumatoid arthritis
Vyas, Deepti, O'Dell, Kate M, Bandy, Jason L, Boyce, Eric G
Published in The Annals of pharmacotherapy (01.11.2013)
Published in The Annals of pharmacotherapy (01.11.2013)
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Pharmacokinetics and bioequivalence of tofacitinib 5 mg in healthy Korean male subjects
Lee, Ji-hyoung, Jeon, Ji-Young, Jang, Kyungho, Kang, Sung Kwon, Kwak, Yong-Geun, Moon, Seol Ju, Kim, Min-Gul
Published in International journal of clinical pharmacology and therapeutics (01.03.2024)
Published in International journal of clinical pharmacology and therapeutics (01.03.2024)
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Contribution of a European‐Prevalent Variant near CD83 and an East Asian–Prevalent Variant near IL17RB to Herpes Zoster Risk in Tofacitinib Treatment: Results of Genome‐Wide Association Study Meta‐Analyses
Bing, Nan, Zhou, Huanyu, Chen, Xing, Hirose, Tomohiro, Kochi, Yuta, Tsuchida, Yumi, Ishigaki, Kazuyoshi, Sumitomo, Shuji, Fujio, Keishi, Zhang, Baohong, Valdez, Hernan, Vincent, Michael S., Martin, David, Clark, James D.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2021)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2021)
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Preferential Inhibition of JAK1 Relative to JAK3 by Upadacitinib: Exposure‐Response Analyses of Ex Vivo Data From 2 Phase 1 Clinical Trials and Comparison to Tofacitinib
Mohamed, Mohamed‐Eslam F., Beck, Denise, Camp, Heidi S., Othman, Ahmed A.
Published in Journal of clinical pharmacology (01.02.2020)
Published in Journal of clinical pharmacology (01.02.2020)
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Lymphocyte modulation by tofacitinib in patients with rheumatoid arthritis
Isailovic, Natasa, Ceribelli, Angela, Cincinelli, Gilberto, Vecellio, Matteo, Guidelli, Giacomo, Caprioli, Marta, Luciano, Nicoletta, Motta, Francesca, Selmi, Carlo, De Santis, Maria
Published in Clinical and experimental immunology (01.08.2021)
Published in Clinical and experimental immunology (01.08.2021)
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AB0777 IDENTIFICATION OF A MICRORNA SIGNATURE PREDICTIVE OF CLINICAL RESPONSE TO TOFACITINIB IN PATIENTS WITH RHEUMATOID ARTHRITIS
Celletti, E., DI Penta, M., Sabatini, E., De Cesare, D., Dionisi, A., Cipollone, F.
Published in Annals of the rheumatic diseases (01.06.2024)
Published in Annals of the rheumatic diseases (01.06.2024)
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Evaluation of tofacitinib citrate bioequivalence based on pharmacokinetic parameters in healthy Chinese subjects
Yu, Bin, Wang, Xiaoru, Yang, Yaru, Lu, Chao, Hu, Wei, Zhang, Xueyuan
Published in International journal of clinical pharmacology and therapeutics (01.04.2021)
Published in International journal of clinical pharmacology and therapeutics (01.04.2021)
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