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Toepfer, Christopher N., Garfinkel, Amanda C., Venturini, Gabriela, Wakimoto, Hiroko, Repetti, Giuliana, Alamo, Lorenzo, Sharma, Arun, Agarwal, Radhika, Ewoldt, Jourdan F., Cloonan, Paige, Letendre, Justin, Lun, Mingyue, Olivotto, Iacopo, Colan, Steve, Ashley, Euan, Jacoby, Daniel, Michels, Michelle, Redwood, Charles S., Watkins, Hugh C., Day, Sharlene M., Staples, James F., Padrón, Raúl, Chopra, Anant, Ho, Carolyn Y., Chen, Christopher S., Pereira, Alexandre C., Seidman, Jonathan G., Seidman, Christine E.
Published in Circulation (New York, N.Y.) (10.03.2020)
Published in Circulation (New York, N.Y.) (10.03.2020)
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SarcTrack
Toepfer, Christopher N, Sharma, Arun, Cicconet, Marcelo, Garfinkel, Amanda C, Mücke, Michael, Neyazi, Meraj, Willcox, Jon A L, Agarwal, Radhika, Schmid, Manuel, Rao, Jyoti, Ewoldt, Jourdan, Pourquié, Olivier, Chopra, Anant, Chen, Christopher S, Seidman, Jonathan G, Seidman, Christine E
Published in Circulation research (12.04.2019)
Published in Circulation research (12.04.2019)
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Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy
Margara, Francesca, Psaras, Yiangos, Wang, Zhinuo Jenny, Schmid, Manuel, Doste, Ruben, Garfinkel, Amanda C., Repetti, Giuliana G., Seidman, Jonathan G., Seidman, Christine E., Rodriguez, Blanca, Toepfer, Christopher N., Bueno-Orovio, Alfonso
Published in Scientific reports (28.12.2022)
Published in Scientific reports (28.12.2022)
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Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor
Guo, Yuxuan, Jardin, Blake D., Zhou, Pingzhu, Sethi, Isha, Akerberg, Brynn N., Toepfer, Christopher N, Ai, Yulan, Li, Yifei, Ma, Qing, Guatimosim, Silvia, Hu, Yongwu, Varuzhanyan, Grigor, VanDusen, Nathan J., Zhang, Donghui, Chan, David C., Yuan, Guo-Cheng, Seidman, Christine E., Seidman, Jonathan G., Pu, William T.
Published in Nature communications (21.09.2018)
Published in Nature communications (21.09.2018)
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GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm
Sharma, Arun, Wasson, Lauren K, Willcox, Jon Al, Morton, Sarah U, Gorham, Joshua M, DeLaughter, Daniel M, Neyazi, Meraj, Schmid, Manuel, Agarwal, Radhika, Jang, Min Young, Toepfer, Christopher N, Ward, Tarsha, Kim, Yuri, Pereira, Alexandre C, DePalma, Steven R, Tai, Angela, Kim, Seongwon, Conner, David, Bernstein, Daniel, Gelb, Bruce D, Chung, Wendy K, Goldmuntz, Elizabeth, Porter, George, Tristani-Firouzi, Martin, Srivastava, Deepak, Seidman, Jonathan G, Seidman, Christine E
Published in eLife (15.10.2020)
Published in eLife (15.10.2020)
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Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation
Venturini, Gabriela, Alvim, Juliana M, Padilha, Kallyandra, Toepfer, Christopher N, Gorham, Joshua M, Wasson, Lauren K, Biagi, Diogo, Schenkman, Sergio, Carvalho, Valdemir M, Salgueiro, Jessica S, Cardozo, Karina H M, Krieger, Jose E, Pereira, Alexandre C, Seidman, Jonathan G, Seidman, Christine E
Published in Frontiers in cellular and infection microbiology (06.02.2023)
Published in Frontiers in cellular and infection microbiology (06.02.2023)
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Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization
Zhang, Kehan, Cloonan, Paige E, Sundaram, Subramanian, Liu, Feng, Das, Shoshana L, Ewoldt, Jourdan K, Bays, Jennifer L, Tomp, Samuel, Toepfer, Christopher N, Marsiglia, Júlia D C, Gorham, Joshua, Reichart, Daniel, Eyckmans, Jeroen, Seidman, Jonathan G, Seidman, Christine E, Chen, Christopher S
Published in Science advances (15.10.2021)
Published in Science advances (15.10.2021)
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Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome
Meier, Anna B., Raj Murthi, Sarala, Rawat, Hilansi, Toepfer, Christopher N., Santamaria, Gianluca, Schmid, Manuel, Mastantuono, Elisa, Schwarzmayr, Thomas, Berutti, Riccardo, Cleuziou, Julie, Ewert, Peter, Görlach, Agnes, Klingel, Karin, Laugwitz, Karl-Ludwig, Seidman, Christine E., Seidman, Jonathan G., Moretti, Alessandra, Wolf, Cordula M.
Published in iScience (21.01.2022)
Published in iScience (21.01.2022)
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A post-MI power struggle: adaptations in cardiac power occur at the sarcomere level alongside MyBP-C and RLC phosphorylation
Toepfer, Christopher N, Sikkel, Markus B, Caorsi, Valentina, Vydyanath, Anupama, Torre, Iratxe, Copeland, O'Neal, Lyon, Alexander R, Marston, Steven B, Luther, Pradeep K, Macleod, Kenneth T, West, Timothy G, Ferenczi, Michael A
Published in American journal of physiology. Heart and circulatory physiology (01.08.2016)
Published in American journal of physiology. Heart and circulatory physiology (01.08.2016)
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Genetic Variants Associated With Cancer Therapy–Induced Cardiomyopathy
Garcia-Pavia, Pablo, Kim, Yuri, Restrepo-Cordoba, Maria Alejandra, Lunde, Ida G, Wakimoto, Hiroko, Smith, Amanda M, Toepfer, Christopher N, Getz, Kelly, Gorham, Joshua, Patel, Parth, Ito, Kaoru, Willcox, Jonathan A, Arany, Zoltan, Li, Jian, Owens, Anjali T, Govind, Risha, Nuñez, Beatriz, Mazaika, Erica, Bayes-Genis, Antoni, Walsh, Roddy, Finkelman, Brian, Lupon, Josep, Whiffin, Nicola, Serrano, Isabel, Midwinter, William, Wilk, Alicja, Bardaji, Alfredo, Ingold, Nathan, Buchan, Rachel, Tayal, Upasana, Pascual-Figal, Domingo A, de Marvao, Antonio, Ahmad, Mian, Garcia-Pinilla, Jose Manuel, Pantazis, Antonis, Dominguez, Fernando, John Baksi, A, O’Regan, Declan P, Rosen, Stuart D, Prasad, Sanjay K, Lara-Pezzi, Enrique, Provencio, Mariano, Lyon, Alexander R, Alonso-Pulpon, Luis, Cook, Stuart A, DePalma, Steven R, Barton, Paul J.R, Aplenc, Richard, Seidman, Jonathan G, Ky, Bonnie, Ware, James S, Seidman, Christine E
Published in Circulation (New York, N.Y.) (02.07.2019)
Published in Circulation (New York, N.Y.) (02.07.2019)
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SarcTrack: An Adaptable Software Tool for Efficient Large-Scale Analysis of Sarcomere Function in hiPSC-Cardiomyocytes
Toepfer, Christopher N, Sharma, Arun, Cicconet, Marcelo, Garfinkel, Amanda C, Mücke, Michael, Neyazi, Meraj, Willcox, Jon A.L, Agarwal, Radhika, Schmid, Manuel, Rao, Jyoti, Ewoldt, Jourdan, Pourquié, Olivier, Chopra, Anant, Chen, Christopher S, Seidman, Jonathan G, Seidman, Christine E
Published in Circulation research (12.04.2019)
Published in Circulation research (12.04.2019)
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Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin
Toepfer, Christopher N, Wakimoto, Hiroko, Garfinkel, Amanda C, McDonough, Barbara, Liao, Dan, Jiang, Jianming, Tai, Angela C, Gorham, Joshua M, Lunde, Ida G, Lun, Mingyue, Lynch, 4th, Thomas L, McNamara, James W, Sadayappan, Sakthivel, Redwood, Charles S, Watkins, Hugh C, Seidman, Jonathan G, Seidman, Christine E
Published in Science translational medicine (23.01.2019)
Published in Science translational medicine (23.01.2019)
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Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation
Agarwal, Radhika, Paulo, Joao A., Toepfer, Christopher N., Ewoldt, Jourdan K., Sundaram, Subramanian, Chopra, Anant, Zhang, Qi, Gorham, Joshua, DePalma, Steven R., Chen, Christopher S., Gygi, Steven P., Seidman, Christine E., Seidman, J.G.
Published in Circulation research (17.09.2021)
Published in Circulation research (17.09.2021)
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CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes
Psaras, Yiangos, Margara, Francesca, Cicconet, Marcelo, Sparrow, Alexander J., Repetti, Giuliana G., Schmid, Manuel, Steeples, Violetta, Wilcox, Jonathan A.L., Bueno-Orovio, Alfonso, Redwood, Charles S., Watkins, Hugh C., Robinson, Paul, Rodriguez, Blanca, Seidman, Jonathan G., Seidman, Christine E., Toepfer, Christopher N.
Published in Circulation research (09.07.2021)
Published in Circulation research (09.07.2021)
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Comparing the effects of chemical Ca2+ dyes and R-GECO on contractility and Ca2+ transients in adult and human iPSC cardiomyocytes
Robinson, Paul, Sparrow, Alexander J., Psaras, Yiangos, Steeples, Violetta, Simon, Jillian N., Broyles, Connor N., Chang, Yu-Fen, Brook, Frances A., Wang, Ying-Jie, Blease, Andrew, Zhang, Xiaoyu, Abassi, Yama A., Geeves, Michael A., Toepfer, Christopher N., Watkins, Hugh, Redwood, Charles, Daniels, Matthew J.
Published in Journal of molecular and cellular cardiology (01.07.2023)
Published in Journal of molecular and cellular cardiology (01.07.2023)
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Novel Therapies for Prevention and Early Treatment of Cardiomyopathies
Repetti, Giuliana G, Toepfer, Christopher N, Seidman, Jonathan G, Seidman, Christine E
Published in Circulation research (24.05.2019)
Published in Circulation research (24.05.2019)
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