Myelodysplastic syndrome progression to acute myeloid leukemia at the stem cell level
Chen, Jiahao, Kao, Yun-Ruei, Sun, Daqian, Todorova, Tihomira I., Reynolds, David, Narayanagari, Swathi-Rao, Montagna, Cristina, Will, Britta, Verma, Amit, Steidl, Ulrich
Published in Nature medicine (01.01.2019)
Published in Nature medicine (01.01.2019)
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Journal Article
Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia
Carvajal, Luis A, Neriah, Daniela Ben, Senecal, Adrien, Benard, Lumie, Thiruthuvanathan, Victor, Yatsenko, Tatyana, Narayanagari, Swathi-Rao, Wheat, Justin C, Todorova, Tihomira I, Mitchell, Kelly, Kenworthy, Charles, Guerlavais, Vincent, Annis, D Allen, Bartholdy, Boris, Will, Britta, Anampa, Jesus D, Mantzaris, Ioannis, Aivado, Manuel, Singer, Robert H, Coleman, Robert A, Verma, Amit, Steidl, Ulrich
Published in Science translational medicine (11.04.2018)
Published in Science translational medicine (11.04.2018)
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Journal Article
Pharmacological inhibition of the transcription factor PU.1 in leukemia
Antony-Debré, Iléana, Paul, Ananya, Leite, Joana, Mitchell, Kelly, Kim, Hye Mi, Carvajal, Luis A, Todorova, Tihomira I, Huang, Kenneth, Kumar, Arvind, Farahat, Abdelbasset A, Bartholdy, Boris, Narayanagari, Swathi-Rao, Chen, Jiahao, Ambesi-Impiombato, Alberto, Ferrando, Adolfo A, Mantzaris, Ioannis, Gavathiotis, Evripidis, Verma, Amit, Will, Britta, Boykin, David W, Wilson, W David, Poon, Gregory Mk, Steidl, Ulrich
Published in The Journal of clinical investigation (01.12.2017)
Published in The Journal of clinical investigation (01.12.2017)
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Journal Article
Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia
Will, Britta, Vogler, Thomas O, Narayanagari, Swathi, Bartholdy, Boris, Todorova, Tihomira I, da Silva Ferreira, Mariana, Chen, Jiahao, Yu, Yiting, Mayer, Jillian, Barreyro, Laura, Carvajal, Luis, Neriah, Daniela Ben, Roth, Michael, van Oers, Johanna, Schaetzlein, Sonja, McMahon, Christine, Edelmann, Winfried, Verma, Amit, Steidl, Ulrich
Published in Nature medicine (01.10.2015)
Published in Nature medicine (01.10.2015)
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Journal Article
Thrombopoietin receptor-independent stimulation of hematopoietic stem cells by eltrombopag
Kao, Yun-Ruei, Chen, Jiahao, Narayanagari, Swathi-Rao, Todorova, Tihomira I, Aivalioti, Maria M, Ferreira, Mariana, Ramos, Pedro M, Pallaud, Celine, Mantzaris, Ioannis, Shastri, Aditi, Bussel, James B, Verma, Amit, Steidl, Ulrich, Will, Britta
Published in Science translational medicine (12.09.2018)
Published in Science translational medicine (12.09.2018)
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Journal Article
IL1RAP potentiates multiple oncogenic signaling pathways in AML
Mitchell, Kelly, Barreyro, Laura, Todorova, Tihomira I, Taylor, Samuel J, Antony-Debré, Iléana, Narayanagari, Swathi-Rao, Carvajal, Luis A, Leite, Joana, Piperdi, Zubair, Pendurti, Gopichand, Mantzaris, Ioannis, Paietta, Elisabeth, Verma, Amit, Gritsman, Kira, Steidl, Ulrich
Published in The Journal of experimental medicine (04.06.2018)
Published in The Journal of experimental medicine (04.06.2018)
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Journal Article
Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS
Barreyro, Laura, Will, Britta, Bartholdy, Boris, Zhou, Li, Todorova, Tihomira I., Stanley, Robert F., Ben-Neriah, Susana, Montagna, Cristina, Parekh, Samir, Pellagatti, Andrea, Boultwood, Jacqueline, Paietta, Elisabeth, Ketterling, Rhett P., Cripe, Larry, Fernandez, Hugo F., Greenberg, Peter L., Tallman, Martin S., Steidl, Christian, Mitsiades, Constantine S., Verma, Amit, Steidl, Ulrich
Published in Blood (09.08.2012)
Published in Blood (09.08.2012)
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Journal Article
MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish
Yu, Young-Mi, Gibbs, Kurt M., Davila, Jonathan, Campbell, Neil, Sung, Simon, Todorova, Tihomira I., Otsuka, Seiji, Sabaawy, Hatem E., Hart, Ronald P., Schachner, Melitta
Published in The European journal of neuroscience (01.05.2011)
Published in The European journal of neuroscience (01.05.2011)
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Journal Article
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment
Will, Britta, Vogler, Thomas O, Bartholdy, Boris, Garrett-Bakelman, Francine, Mayer, Jillian, Barreyro, Laura, Pandolfi, Ashley, Todorova, Tihomira I, Okoye-Okafor, Ujunwa C, Stanley, Robert F, Bhagat, Tushar D, Verma, Amit, Figueroa, Maria E, Melnick, Ari, Roth, Michael, Steidl, Ulrich
Published in Nature immunology (01.05.2013)
Published in Nature immunology (01.05.2013)
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Journal Article
H2.0-like Homeobox Regulates Early Hematopoiesis and Promotes Acute Myeloid Leukemia
Kawahara, Masahiro, Pandolfi, Ashley, Bartholdy, Boris, Barreyro, Laura, Will, Britta, Roth, Michael, Okoye-Okafor, Ujunwa C., Todorova, Tihomira I., Figueroa, Maria E., Melnick, Ari, Mitsiades, Constantine S., Steidl, Ulrich
Published in Cancer cell (14.08.2012)
Published in Cancer cell (14.08.2012)
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Journal Article
Publisher Correction: Myelodysplastic syndrome progression to acute myeloid leukemia at the stem cell level
Chen, Jiahao, Kao, Yun-Ruei, Sun, Daqian, Todorova, Tihomira I., Reynolds, David, Narayanagari, Swathi-Rao, Montagna, Cristina, Will, Britta, Verma, Amit, Steidl, Ulrich
Published in Nature medicine (01.03.2019)
Published in Nature medicine (01.03.2019)
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Journal Article
MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
Ueda, Koki, Kumari, Rajni, Schwenger, Emily, Wheat, Justin C., Bohorquez, Oliver, Narayanagari, Swathi-Rao, Taylor, Samuel J., Carvajal, Luis A., Pradhan, Kith, Bartholdy, Boris, Todorova, Tihomira I., Goto, Hiroki, Sun, Daqian, Chen, Jiahao, Shan, Jidong, Song, Yinghui, Montagna, Cristina, Xiong, Shunbin, Lozano, Guillermina, Pellagatti, Andrea, Boultwood, Jacqueline, Verma, Amit, Steidl, Ulrich
Published in Cancer cell (12.04.2021)
Published in Cancer cell (12.04.2021)
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Journal Article
A myeloid tumor suppressor role for NOL3
Stanley, Robert F, Piszczatowski, Richard T, Bartholdy, Boris, Mitchell, Kelly, McKimpson, Wendy M, Narayanagari, Swathi, Walter, Dagmar, Todorova, Tihomira I, Hirsch, Cassandra, Makishima, Hideki, Will, Britta, McMahon, Christine, Gritsman, Kira, Maciejewski, Jaroslaw P, Kitsis, Richard N, Steidl, Ulrich
Published in The Journal of experimental medicine (06.03.2017)
Published in The Journal of experimental medicine (06.03.2017)
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Journal Article
HSC commitment-associated epigenetic signature is prognostic in acute myeloid leukemia
Bartholdy, Boris, Christopeit, Maximilian, Will, Britta, Mo, Yongkai, Barreyro, Laura, Yu, Yiting, Bhagat, Tushar D, Okoye-Okafor, Ujunwa C, Todorova, Tihomira I, Greally, John M, Levine, Ross L, Melnick, Ari, Verma, Amit, Steidl, Ulrich
Published in The Journal of clinical investigation (01.03.2014)
Published in The Journal of clinical investigation (01.03.2014)
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Journal Article
Transcriptional regulators CITED2 and PU.1 cooperate in maintaining hematopoietic stem cells
Mattes, Katharina, Geugien, Marjan, Korthuis, Patrick M., Brouwers-Vos, Annet Z., Fehrmann, Rudolf S.N., Todorova, Tihomira I., Steidl, Ulrich, Vellenga, Edo, Schepers, Hein
Published in Experimental hematology (01.05.2019)
Published in Experimental hematology (01.05.2019)
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Journal Article
Role of IL8 in myeloid malignancies
Ramachandra, Nandini, Gupta, Malini, Schwartz, Leya, Todorova, Tihomira, Shastri, Aditi, Will, Britta, Steidl, Ulrich, Verma, Amit
Published in Leukemia & lymphoma (01.11.2023)
Published in Leukemia & lymphoma (01.11.2023)
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Journal Article
3008 – INTERCEPTING PROGRESSION TO LEUKEMIA IN A NOVEL RUNX1-FPD MOUSE MODEL
Goto, Hiroki, Todorova, Tihomira, Schwenger, Emily, Taylor, Samuel, Chen, Sisi, Narayanagari, Swathi-Rao, Sun, Daqian, Bohorquez, Oliver, Kumari, Rajni, Sundaravel, Sriram, Tatsumi, Goichi, Ueda, Koki, Edelmann, Winfried, Abdel-Wahab, Omar, Shastri, Aditi, Verma, Amit, Steidl, Ulrich
Published in Experimental hematology (2023)
Published in Experimental hematology (2023)
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Journal Article
Regulation of hematopoietic stem cell fate by special at-rich sequence binding protein 1
Will, Britta, Todorova, Tihomira, Verma, Amit, Steidl, Ulrich, Melnick, Ari
Published in Experimental hematology (01.08.2014)
Published in Experimental hematology (01.08.2014)
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Journal Article
MDS Progression to AML at the Stem Cell Level
Chen, Jiahao, Kao, Yun-Ruei, Sun, Daqian, Todorova, Tihomira, Reynolds, David, Narayanagari, Swathi-Rao, Thiruthuvanathan, Victor, Montagna, Cristina, Will, Britta, Verma, Amit, Steidl, Ulrich
Published in Experimental hematology (01.08.2018)
Published in Experimental hematology (01.08.2018)
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Journal Article
2026 - MDS Progression to AML at the Stem Cell Level
Chen, Jiahao, Kao, Yun-Ruei, Sun, Daqian, Todorova, Tihomira, Reynolds, David, Narayanagari, Swathi-Rao, Thiruthuvanathan, Victor, Montagna, Cristina, Will, Britta, Verma, Amit, Steidl, Ulrich
Published in Experimental hematology (01.08.2018)
Published in Experimental hematology (01.08.2018)
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