The endolysosomal pathway and ALS/FTD
Todd, Tiffany W, Shao, Wei, Zhang, Yong-Jie, Petrucelli, Leonard
Published in Trends in neurosciences (Regular ed.) (01.12.2023)
Published in Trends in neurosciences (Regular ed.) (01.12.2023)
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Journal Article
Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD
Wu, Yanwei, Shao, Wei, Todd, Tiffany W., Tong, Jimei, Yue, Mei, Koga, Shunsuke, Castanedes-Casey, Monica, Librero, Ariston L., Lee, Chris W., Mackenzie, Ian R., Dickson, Dennis W., Zhang, Yong-Jie, Petrucelli, Leonard, Prudencio, Mercedes
Published in Cell reports (Cambridge) (24.08.2021)
Published in Cell reports (Cambridge) (24.08.2021)
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Journal Article
Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration
Shao, Wei, Todd, Tiffany W, Wu, Yanwei, Jones, Caroline Y, Tong, Jimei, Jansen-West, Karen, Daughrity, Lillian M, Park, Jinyoung, Koike, Yuka, Kurti, Aishe, Yue, Mei, Castanedes-Casey, Monica, Del Rosso, Giulia, Dunmore, Judith A, Zanetti Alepuz, Desiree, Oskarsson, Björn, Dickson, Dennis W, Cook, Casey N, Prudencio, Mercedes, Gendron, Tania F, Fryer, John D, Zhang, Yong-Jie, Petrucelli, Leonard
Published in Science (American Association for the Advancement of Science) (07.10.2022)
Published in Science (American Association for the Advancement of Science) (07.10.2022)
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Journal Article
Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43
Castellanos Otero, Paula, Todd, Tiffany W, Shao, Wei, Jones, Caroline J, Huang, Kexin, Daughrity, Lillian M, Yue, Mei, Sheth, Udit, Gendron, Tania F, Prudencio, Mercedes, Oskarsson, Björn, Dickson, Dennis W, Petrucelli, Leonard, Zhang, Yong-Jie
Published in PloS one (18.04.2024)
Published in PloS one (18.04.2024)
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Journal Article
Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo
Todd, Tiffany W., McEachin, Zachary T., Chew, Jeannie, Burch, Alexander R., Jansen-West, Karen, Tong, Jimei, Yue, Mei, Song, Yuping, Castanedes-Casey, Monica, Kurti, Aishe, Dunmore, Judith H., Fryer, John D., Zhang, Yong-Jie, San Millan, Beatriz, Teijeira Bautista, Susana, Arias, Manuel, Dickson, Dennis, Gendron, Tania F., Sobrido, María-Jesús, Disney, Matthew D., Bassell, Gary J., Rossoll, Wilfried, Petrucelli, Leonard
Published in Cell reports (Cambridge) (05.05.2020)
Published in Cell reports (Cambridge) (05.05.2020)
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Journal Article
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia
Marks, Jordan D, Ayuso, Virginia Estades, Carlomagno, Yari, Yue, Mei, Todd, Tiffany W, Hao, Ying, Li, Ziyi, McEachin, Zachary T, Shantaraman, Anantharaman, Duong, Duc M, Daughrity, Lillian M, Jansen-West, Karen, Shao, Wei, Calliari, Anna, Bejarano, Jesus Gonzalez, DeTure, Michael, Rawlinson, Bailey, Casey, Monica Castanedes, Lilley, Meredith T, Donahue, Megan H, Jawahar, Vidhya Maheswari, Boeve, Bradley F, Petersen, Ronald C, Knopman, David S, Oskarsson, Björn, Graff-Radford, Neill R, Wszolek, Zbigniew K, Dickson, Dennis W, Josephs, Keith A, Qi, Yue A, Seyfried, Nicholas T, Ward, Michael E, Zhang, Yong-Jie, Prudencio, Mercedes, Petrucelli, Leonard, Cook, Casey N
Published in Science translational medicine (17.01.2024)
Published in Science translational medicine (17.01.2024)
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Journal Article
TDP-43-regulated cryptic RNAs accumulate in Alzheimer's disease brains
Estades Ayuso, Virginia, Pickles, Sarah, Todd, Tiffany, Yue, Mei, Jansen-West, Karen, Song, Yuping, González Bejarano, Jesús, Rawlinson, Bailey, DeTure, Michael, Graff-Radford, Neill R, Boeve, Bradley F, Knopman, David S, Petersen, Ronald C, Dickson, Dennis W, Josephs, Keith A, Petrucelli, Leonard, Prudencio, Mercedes
Published in Molecular neurodegeneration (21.08.2023)
Published in Molecular neurodegeneration (21.08.2023)
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Journal Article
Polyglutamine disease toxicity is regulated by Nemo-like kinase in spinocerebellar ataxia type 1
Ju, Hyoungseok, Kokubu, Hiroshi, Todd, Tiffany W, Kahle, Juliette J, Kim, Soeun, Richman, Ronald, Chirala, Karthik, Orr, Harry T, Zoghbi, Huda Y, Lim, Janghoo
Published in The Journal of neuroscience (29.05.2013)
Published in The Journal of neuroscience (29.05.2013)
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Journal Article
Plasma PolyQ-ATXN3 Levels Associate With Cerebellar Degeneration and Behavioral Abnormalities in a New AAV-Based SCA3 Mouse Model
Jansen-West, Karen, Todd, Tiffany W, Daughrity, Lillian M, Yue, Mei, Tong, Jimei, Carlomagno, Yari, Del Rosso, Giulia, Kurti, Aishe, Jones, Caroline Y, Dunmore, Judith A, Castanedes-Casey, Monica, Dickson, Dennis W, Wszolek, Zbigniew K, Fryer, John D, Petrucelli, Leonard, Prudencio, Mercedes
Published in Frontiers in cell and developmental biology (21.03.2022)
Published in Frontiers in cell and developmental biology (21.03.2022)
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Journal Article
Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy
Todd, Tiffany W, Kokubu, Hiroshi, Miranda, Helen C, Cortes, Constanza J, La Spada, Albert R, Lim, Janghoo
Published in eLife (26.08.2015)
Published in eLife (26.08.2015)
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Journal Article
HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS
Del Rosso, Giulia, Carlomagno, Yari, Todd, Tiffany W, Jones, Caroline Y, Prudencio, Mercedes, Daughrity, Lillian M, Yue, Mei, Jansen-West, Karen, Tong, Jimei, Shao, Wei, Wu, Yanwei, Castanedes-Casey, Monica, Tabassian, Lilia, Oskarsson, Björn, Ling, Karen, Rigo, Frank, Dickson, Dennis W, Yao, Tso-Pang, Petrucelli, Leonard, Cook, Casey N, Zhang, Yong Jie
Published in Frontiers in cell and developmental biology (12.01.2022)
Published in Frontiers in cell and developmental biology (12.01.2022)
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Journal Article
Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36
McEachin, Zachary T., Gendron, Tania F., Raj, Nisha, García-Murias, María, Banerjee, Anwesha, Purcell, Ryan H., Ward, Patricia J., Todd, Tiffany W., Merritt-Garza, Megan E., Jansen-West, Karen, Hales, Chadwick M., García-Sobrino, Tania, Quintáns, Beatriz, Holler, Christopher J., Taylor, Georgia, San Millán, Beatriz, Teijeira, Susana, Yamashita, Toru, Ohkubo, Ryuichi, Boulis, Nicholas M., Xu, Chongchong, Wen, Zhexing, Streichenberger, Nathalie, Fogel, Brent L., Kukar, Thomas, Abe, Koji, Dickson, Dennis W., Arias, Manuel, Glass, Jonathan D., Jiang, Jie, Tansey, Malú G., Sobrido, María-Jesús, Petrucelli, Leonard, Rossoll, Wilfried, Bassell, Gary J.
Published in Neuron (Cambridge, Mass.) (22.07.2020)
Published in Neuron (Cambridge, Mass.) (22.07.2020)
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