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Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
Toyn, Jeremy H., Boy, Kenneth M., Raybon, Joseph, Meredith, Jere E., Robertson, Alan S., Guss, Valerie, Hoque, Nina, Sweeney, Francis, Zhuo, Xiaoliang, Clarke, Wendy, Snow, Kimberly, Denton, R. Rex, Zuev, Dmitry, Thompson, Lorin A., Morrison, John, Grace, James, Berisha, Flora, Furlong, Michael, Wang, Jun-Sheng, Lentz, Kimberly A., Padmanabha, Ramesh, Cook, Lynda, Wei, Cong, Drexler, Dieter M., Macor, John E., Albright, Charlie F., Gasior, Maciej, Olson, Richard E., Hong, Quan, Soares, Holly D., AbuTarif, Malaz, Ahlijanian, Michael K.
Published in The Journal of pharmacology and experimental therapeutics (01.07.2016)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2016)
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Effects of leucine and its metabolite β‐hydroxy‐β‐methylbutyrate on human skeletal muscle protein metabolism
Wilkinson, D. J., Hossain, T., Hill, D. S., Phillips, B. E., Crossland, H., Williams, J., Loughna, P., Churchward‐Venne, T. A., Breen, L., Phillips, S. M., Etheridge, T., Rathmacher, J. A., Smith, K., Szewczyk, N. J., Atherton, P. J.
Published in The Journal of physiology (01.06.2013)
Published in The Journal of physiology (01.06.2013)
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Pulmonary hyperpolarized (129) Xe morphometry for mapping xenon gas concentrations and alveolar oxygen partial pressure: Proof-of-concept demonstration in healthy and COPD subjects
Ouriadov, A, Farag, A, Kirby, M, McCormack, D G, Parraga, G, Santyr, G E
Published in Magnetic resonance in medicine (01.12.2015)
Published in Magnetic resonance in medicine (01.12.2015)
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The metabolism and disposition of GSK2140944 in healthy human subjects
Negash, Kitaw, Andonian, Clara, Felgate, Clive, Chen, Cathy, Goljer, Igor, Squillaci, Bianca, Nguyen, Dung, Pirhalla, Jill, Lev, Mally, Schubert, Ernest, Tiffany, Courtney, Hossain, Mohammad, Ho, May
Published in Xenobiotica (02.08.2016)
Published in Xenobiotica (02.08.2016)
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Branched-chain and aromatic amino acids, insulin resistance and liver specific ectopic fat storage in overweight to obese subjects
Haufe, S., Witt, H., Engeli, S., Kaminski, J., Utz, W., Fuhrmann, J.C., Rein, D., Schulz-Menger, J., Luft, F.C., Boschmann, M., Jordan, J.
Published in Nutrition, metabolism, and cardiovascular diseases (01.07.2016)
Published in Nutrition, metabolism, and cardiovascular diseases (01.07.2016)
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Validation of a microdose probe drug cocktail for clinical drug interaction assessments for drug transporters and CYP3A
Prueksaritanont, T, Tatosian, D A, Chu, X, Railkar, R, Evers, R, Chavez-Eng, C, Lutz, R, Zeng, W, Yabut, J, Chan, G H, Cai, X, Latham, A H, Hehman, J, Stypinski, D, Brejda, J, Zhou, C, Thornton, B, Bateman, K P, Fraser, I, Stoch, S A
Published in Clinical pharmacology and therapeutics (01.04.2017)
Published in Clinical pharmacology and therapeutics (01.04.2017)
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Gannet: A batch-processing tool for the quantitative analysis of gamma-aminobutyric acid-edited MR spectroscopy spectra
Edden, Richard A.E., Puts, Nicolaas A.J., Harris, Ashley D., Barker, Peter B., Evans, C. John
Published in Journal of magnetic resonance imaging (01.12.2014)
Published in Journal of magnetic resonance imaging (01.12.2014)
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Gender- and Age-Associated Differences in Bone Marrow Adipose Tissue and Bone Marrow Fat Unsaturation Throughout the Skeleton, Quantified Using Chemical Shift Encoding-Based Water–Fat MRI
Beekman, Kerensa M., Regenboog, Martine, Nederveen, Aart J., Bravenboer, Nathalie, den Heijer, Martin, Bisschop, Peter H., Hollak, Carla E., Akkerman, Erik M., Maas, Mario
Published in Frontiers in endocrinology (Lausanne) (27.04.2022)
Published in Frontiers in endocrinology (Lausanne) (27.04.2022)
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Radiation dosimetry and pharmacokinetics of florbetapir (18F) in Japanese subjects
Nakano, Masako, Nakamura, Tomomi, Takita, Yasushi, Uenaka, Kazunori, Ando, Tomoaki, Senda, Michio, Joshi, Abhinay D., Lu, Ming, Breault, Christopher, Pontecorvo, Michael J.
Published in Annals of nuclear medicine (01.08.2019)
Published in Annals of nuclear medicine (01.08.2019)
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Determination of bosutinib in mice plasma and tissue by UPLC-MS/MS and its application to the pharmacokinetic and tissue distribution study
Wang, Linxia, Tang, Luming, Zheng, Yi, Pan, Guoquan, Zhu, Wei, Pan, Chenwei, Zhu, Lihe
Published in Analytical methods (01.01.2015)
Published in Analytical methods (01.01.2015)
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Characteristics of metabolically obese normal-weight (MONW) subjects
Conus, Florence, Rabasa-Lhoret, Rémi, Péronnet, François
Published in Applied physiology, nutrition, and metabolism (01.02.2007)
Published in Applied physiology, nutrition, and metabolism (01.02.2007)
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Altered deposition of inhaled nanoparticles in subjects with chronic obstructive pulmonary disease
Jakobsson, Jonas K F, Aaltonen, H Laura, Nicklasson, Hanna, Gudmundsson, Anders, Rissler, Jenny, Wollmer, Per, Löndahl, Jakob
Published in BMC pulmonary medicine (06.08.2018)
Published in BMC pulmonary medicine (06.08.2018)
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FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise
Huh, Joo Young, Panagiotou, Grigorios, Mougios, Vassilis, Brinkoetter, Mary, Vamvini, Maria T., Schneider, Benjamin E., Mantzoros, Christos S.
Published in Metabolism, clinical and experimental (01.12.2012)
Published in Metabolism, clinical and experimental (01.12.2012)
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Regional mapping of gas uptake by blood and tissue in the human lung using hyperpolarized xenon-129 MRI
Qing, Kun, Ruppert, Kai, Jiang, Yun, Mata, Jaime F., Miller, G. Wilson, Shim, Y. Michael, Wang, Chengbo, Ruset, Iulian C., Hersman, F. William, Altes, Talissa A., Mugler III, John P.
Published in Journal of magnetic resonance imaging (01.02.2014)
Published in Journal of magnetic resonance imaging (01.02.2014)
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Optimal Target Region for Subject Classification on the Basis of Amyloid PET Images
Carbonell, Felix, Zijdenbos, Alex P., Charil, Arnaud, Grand’Maison, Marilyn, Bedell, Barry J.
Published in Journal of Nuclear Medicine (01.09.2015)
Published in Journal of Nuclear Medicine (01.09.2015)
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The biological activity and tissue distribution of 2′,3′-dihydrophylloquinone in rats
Sato, Toshiro, Ozaki, Rumi, Kamo, Shuichi, Hara, Yusuke, Konishi, Satoru, Isobe, Yosuke, Saitoh, Sanshiroh, Harada, Hiroshi
Published in Biochimica et biophysica acta (22.08.2003)
Published in Biochimica et biophysica acta (22.08.2003)
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Heterogeneous tissue distribution of a mitochondrial DNA polymorphism in heteroplasmic subjects without mitochondrial disorders
Kirches, Elmar, Michael, Matthias, Warich-Kirches, Michaela, Schneider, Thomas, Weis, Serge, Krause, Guido, Mawrin, Christian, Dietzmann, Knut
Published in Journal of medical genetics (01.05.2001)
Published in Journal of medical genetics (01.05.2001)
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