Modeling antisense oligonucleotide therapy in MECP2 duplication syndrome human iPSC-derived neurons reveals gene expression programs responsive to MeCP2 levels
Bajikar, Sameer S, Sztainberg, Yehezkel, Trostle, Alexander J, Tirumala, Harini P, Wan, Ying-Wooi, Harrop, Caroline L, Bengtsson, Jesse D, Carvalho, Claudia M B, Pehlivan, Davut, Suter, Bernhard, Neul, Jeffrey L, Liu, Zhandong, Jafar-Nejad, Paymaan, Rigo, Frank, Zoghbi, Huda Y
Published in Human molecular genetics (15.09.2024)
Published in Human molecular genetics (15.09.2024)
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Identification and characterization of conserved noncoding cis -regulatory elements that impact Mecp2 expression and neurological functions
Shao, Yingyao, Bajikar, Sameer S, Tirumala, Harini P, Gutierrez, Manuel Cantu, Wythe, Joshua D, Zoghbi, Huda Y
Published in Genes & development (01.04.2021)
Published in Genes & development (01.04.2021)
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A novel pathogenic mutation of MeCP2 impairs chromatin association independent of protein levels
Zhou, Jian, Cattoglio, Claudia, Shao, Yingyao, Tirumala, Harini P, Vetralla, Carlo, Bajikar, Sameer S, Li, Yan, Chen, Hu, Wang, Qi, Wu, Zhenyu, Tang, Bing, Zahabiyon, Mahla, Bajic, Aleksandar, Meng, Xiangling, Ferrie, Jack J, LaGrone, Anel, Zhang, Ping, Kim, Jean J, Tang, Jianrong, Liu, Zhandong, Darzacq, Xavier, Heintz, Nathaniel, Tjian, Robert, Zoghbi, Huda Y
Published in Genes & development (01.10.2023)
Published in Genes & development (01.10.2023)
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