miR-150 regulates the development of NK and iNKT cells
Bezman, Natalie A, Chakraborty, Tirtha, Bender, Timothy, Lanier, Lewis L
Published in The Journal of experimental medicine (19.12.2011)
Published in The Journal of experimental medicine (19.12.2011)
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Journal Article
Regulation of MicroRNA Expression and Abundance during Lymphopoiesis
Kuchen, Stefan, Resch, Wolfgang, Yamane, Arito, Kuo, Nan, Li, Zhiyu, Chakraborty, Tirtha, Wei, Lai, Laurence, Arian, Yasuda, Tomoharu, Peng, Siying, Hu-Li, Jane, Lu, Kristina, Dubois, Wendy, Kitamura, Yoshiaki, Charles, Nicolas, Sun, Hong-wei, Muljo, Stefan, Schwartzberg, Pamela L., Paul, William E., O'Shea, John, Rajewsky, Klaus, Casellas, Rafael
Published in Immunity (Cambridge, Mass.) (25.06.2010)
Published in Immunity (Cambridge, Mass.) (25.06.2010)
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Journal Article
Dicer Ablation Affects Antibody Diversity and Cell Survival in the B Lymphocyte Lineage
Koralov, Sergei B., Muljo, Stefan A., Galler, Gunther R., Krek, Azra, Chakraborty, Tirtha, Kanellopoulou, Chryssa, Jensen, Kari, Cobb, Bradley S., Merkenschlager, Matthias, Rajewsky, Nikolaus, Rajewsky, Klaus
Published in Cell (07.03.2008)
Published in Cell (07.03.2008)
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Journal Article
Two Forms of Loops Generate the Chromatin Conformation of the Immunoglobulin Heavy-Chain Gene Locus
Guo, Changying, Gerasimova, Tatiana, Hao, Haiping, Ivanova, Irina, Chakraborty, Tirtha, Selimyan, Roza, Oltz, Eugene M., Sen, Ranjan
Published in Cell (14.10.2011)
Published in Cell (14.10.2011)
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Journal Article
Immune Surveillance and Therapy of Lymphomas Driven by Epstein-Barr Virus Protein LMP1 in a Mouse Model
Zhang, Baochun, Kracker, Sven, Yasuda, Tomoharu, Casola, Stefano, Vanneman, Matthew, Hömig-Hölzel, Cornelia, Wang, Zhe, Derudder, Emmanuel, Li, Shuang, Chakraborty, Tirtha, Cotter, Shane E., Koyama, Shohei, Currie, Treeve, Freeman, Gordon J., Kutok, Jeffery L., Rodig, Scott J., Dranoff, Glenn, Rajewsky, Klaus
Published in Cell (17.02.2012)
Published in Cell (17.02.2012)
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Journal Article
miR-142 favors naïve B cell residence in peripheral lymph nodes
Hagen, Magdalena, Chakraborty, Tirtha, Olson, William J., Heitz, Martin, Hermann-Kleiter, Natascha, Kimpel, Janine, Jenewein, Brigitte, Pertoll, Johanna, Labi, Verena, Rajewsky, Klaus, Derudder, Emmanuel
Published in Frontiers in immunology (10.11.2022)
Published in Frontiers in immunology (10.11.2022)
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Journal Article
Development of a gene edited next-generation hematopoietic cell transplant to enable acute myeloid leukemia treatment by solving off-tumor toxicity
Lydeard, John R., Lin, Michelle I., Ge, Huanying Gary, Halfond, Amanda, Wang, Shu, Jones, Mark B., Etchin, Julia, Angelini, Gabriella, Xavier-Ferrucio, Juliana, Lisle, Jessica, Salvadore, Kienan, Keschner, Yonina, Mager, Hannah, Scherer, Julian, Hu, Jianxin, Mukherjee, Siddhartha, Chakraborty, Tirtha
Published in Molecular therapy. Methods & clinical development (14.12.2023)
Published in Molecular therapy. Methods & clinical development (14.12.2023)
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Journal Article
260 Novel CLL-1-directed CAR-T cells mediate potent antigen-specific cytolytic activity in mouse models of acute myeloid leukemia
Gjeci, Brikena, Williams, Reid, Hoyt, Hillary, Halfond, Amanda, Canesin, Giacomo, Etchin, Julia, Mundelboim, Guy, Silva, Mariana, Lydeard, John, Scherer, Julian, Chakraborty, Tirtha
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
A 220-nucleotide deletion of the intronic enhancer reveals an epigenetic hierarchy in immunoglobulin heavy chain locus activation
Chakraborty, Tirtha, Perlot, Thomas, Subrahmanyam, Ramesh, Jani, Anant, Goff, Peter H, Zhang, Yu, Ivanova, Irina, Alt, Frederick W, Sen, Ranjan
Published in The Journal of experimental medicine (11.05.2009)
Published in The Journal of experimental medicine (11.05.2009)
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Journal Article
The P Domain of the P0 Protein of Plasmodium falciparum Protects against Challenge with Malaria Parasites
Rajeshwari, K, Patel, Kalpesh, Nambeesan, Savithri, Mehta, Monika, Sehgal, Alfica, Chakraborty, Tirtha, Sharma, Shobhona
Published in Infection and Immunity (01.09.2004)
Published in Infection and Immunity (01.09.2004)
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Journal Article
N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density
Svitkin, Yuri V, Cheng, Yi Min, Chakraborty, Tirtha, Presnyak, Vladimir, John, Matthias, Sonenberg, Nahum
Published in Nucleic acids research (02.06.2017)
Published in Nucleic acids research (02.06.2017)
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Journal Article
A Plant Homeodomain in Rag-2 that Binds Hypermethylated Lysine 4 of Histone H3 Is Necessary for Efficient Antigen-Receptor-Gene Rearrangement
Liu, Yun, Subrahmanyam, Ramesh, Chakraborty, Tirtha, Sen, Ranjan, Desiderio, Stephen
Published in Immunity (Cambridge, Mass.) (01.10.2007)
Published in Immunity (Cambridge, Mass.) (01.10.2007)
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Journal Article
Multimodal Atlas of Paired Diagnosis and Relapse AML Samples Enables Novel Therapeutic Targeting of Surface Antigens
Halfond, Amanda, Ung, Matthew, Etchin, Julia, Keschner, Yonina, DiFazio, Julia, Pyclik, Alyssa, Mundelboim, Guy, Ge, Gary, Lydeard, John, Chakraborty, Tirtha
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Longitudinal Multimodal Atlas of AML Surface Antigens Enables Adaptive and Combinatorial Targeting
Etchin, Julia, Ung, Matthew, Halfond, Amanda, Keschner, Yonina, DiFazio, Julia, Mundelboim, Guy, Ge, Gary, Lydeard, John, Chakraborty, Tirtha
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
MicroRNAs Enable mRNA Therapeutics to Selectively Program Cancer Cells to Self-Destruct
Jain, Ruchi, Frederick, Josh P., Huang, Eric Y., Burke, Kristine E., Mauger, David M., Andrianova, Elizaveta A., Farlow, Sam J., Siddiqui, Summar, Pimentel, Jeffrey, Cheung-Ong, Kahlin, McKinney, Kristine M., Köhrer, Caroline, Moore, Melissa J., Chakraborty, Tirtha
Published in Nucleic acid therapeutics (01.10.2018)
Published in Nucleic acid therapeutics (01.10.2018)
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Journal Article
G-CSF/Plerixafor Dual-Mobilized Donor Derived CD33CAR T-Cells As Potent and Effective AML Therapy in Pre-Clinical Models
Canesin, Giacomo, Hoyt, Hillary, Williams, Reid, Silva, Mariana, Chng, Melissa, Cummins, Christopher, Ung, Matthew, Qiu, Huan, Shin, John, Hu, Jianxin, Ge, Gary, Scherer, Julian, Chakraborty, Tirtha, Kassim, Sadik
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Efficient Multiplex Gene Editing of CD33 and CLL-1 in Human Hematopoietic Stem Cells Enables the Potential of Next-Generation Transplants for AML Treatment
Xavier-Ferrucio, Juliana, Angelini, Gabriella, Krishnamurthy, Sushma, Patel, Nipul, Pettiglio, Michael, Collingsworth, Timothy, Halfond, Amanda, Etchin, Julia, Keschner, Yonina, Mundelboim, Guy, Qiu, Huan, Wang, Ruijia, Ge, Gary, Lydeard, John, Lin, Michelle I, Chakraborty, Tirtha
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
CD33-Deleted Hematopoietic Cells (Trem-Cel) Are Protected from CD33xCD3 Bispecific Antibody Treatment and Produce Significantly Reduced Levels of Inflammatory Cytokines in Preclinical Studies
Lisle, Jessica, Krishnamurthy, Sushma, Halfond, Amanda, Pechilis, Lisa, Manalo, Nate, Chng, Melissa, Gjeci, Brikena, Angelini, Gabriella, Norman, Fulton, Lourenco, Caitlin, Mager, Hannah, Etchin, Julia, Keschner, Yonina, Silva, Mariana, Mattson, Bethany, Barreyro, Laura, Guttke, Christina, Lydeard, John, Scherer, Julian, Lin, Michelle I, Chakraborty, Tirtha
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Knock out of CD123 or CLL-1 By CRISPR-Cas9 Editing from Human Hematopoietic Stem Cell Transplants Provide New Possibilities for Increasing Therapeutic Index and Safety for AML Treatment
Luo, Chong, Angelini, Gabriella, Krishnamurthy, Sushma, Lisle, Jessica, Isik, Meltem, Ghdossi, Azita, Cummins, Christopher, Pettiglio, Michael, Hazelbaker, Dane, Ge, Gary, Tavares, Patrick, Nikam, Mugdha, Paik, Elizabeth, Lydeard, John, Lin, Michelle, Chakraborty, Tirtha
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Multiplex Engineering of Human CD34+ HSPCs Enables Dual Gene Knock-out While Maintaining High Engraftment Potential and Safety
Patel, Nipul, Pettiglio, Michael, Cummins, Christopher, Pimentel, Jeff, Kapuria, Anjali, Ghodssi, Azita, Isik, Meltem, Falla, Alejandra, Amunugama, Ravindra, Lisle, Jessica, Wang, Shu, Lin, Michelle, Lydeard, John, Ge, Gary, Hazelbaker, Dane, Paik, Elizabeth, Chakraborty, Tirtha
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article