Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus
Jenks, Scott A., Cashman, Kevin S., Zumaquero, Esther, Marigorta, Urko M., Patel, Aakash V., Wang, Xiaoqian, Tomar, Deepak, Woodruff, Matthew C., Simon, Zoe, Bugrovsky, Regina, Blalock, Emily L., Scharer, Christopher D., Tipton, Christopher M., Wei, Chungwen, Lim, S. Sam, Petri, Michelle, Niewold, Timothy B., Anolik, Jennifer H., Gibson, Greg, Lee, F. Eun-Hyung, Boss, Jeremy M., Lund, Frances E., Sanz, Ignacio
Published in Immunity (Cambridge, Mass.) (16.10.2018)
Published in Immunity (Cambridge, Mass.) (16.10.2018)
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Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus
Tipton, Christopher M, Fucile, Christopher F, Darce, Jaime, Chida, Asiya, Ichikawa, Travis, Gregoretti, Ivan, Schieferl, Sandra, Hom, Jennifer, Jenks, Scott, Feldman, Ron J, Mehr, Ramit, Wei, Chungwen, Lee, F Eun-Hyung, Cheung, Wan Cheung, Rosenberg, Alexander F, Sanz, Iñaki
Published in Nature immunology (01.07.2015)
Published in Nature immunology (01.07.2015)
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Understanding B‐cell activation and autoantibody repertoire selection in systemic lupus erythematosus: A B‐cell immunomics approach
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Smith, Fauna L, Savage, Hannah P, Luo, Zheng, Tipton, Christopher M, Lee, F Eun-Hyung, Apostol, April C, Beaudin, Anna E, Lopez, Diego A, Jensen, Ingvill, Keller, Stefan, Baumgarth, Nicole
Published in The Journal of experimental medicine (03.04.2023)
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Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function
Portugal, Silvia, Tipton, Christopher M, Sohn, Haewon, Kone, Younoussou, Wang, Jing, Li, Shanping, Skinner, Jeff, Virtaneva, Kimmo, Sturdevant, Daniel E, Porcella, Stephen F, Doumbo, Ogobara K, Doumbo, Safiatou, Kayentao, Kassoum, Ongoiba, Aissata, Traore, Boubacar, Sanz, Inaki, Pierce, Susan K, Crompton, Peter D
Published in eLife (08.05.2015)
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Understanding and measuring human B‐cell tolerance and its breakdown in autoimmune disease
Cashman, Kevin S., Jenks, Scott A., Woodruff, Matthew C., Tomar, Deepak, Tipton, Christopher M., Scharer, Christopher D., Eun‐Hyung Lee, F., Boss, Jeremy M., Sanz, Iñaki
Published in Immunological reviews (01.11.2019)
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Lineage Reconstruction of In Vitro Identified Antigen-Specific Autoreactive B Cells from Adaptive Immune Receptor Repertoires
Blazso, Peter, Csomos, Krisztian, Tipton, Christopher M, Ujhazi, Boglarka, Walter, Jolan E
Published in International journal of molecular sciences (23.12.2022)
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GLaMST: grow lineages along minimum spanning tree for b cell receptor sequencing data
Yang, Xingyu, Tipton, Christopher M, Woodruff, Matthew C, Zhou, Enlu, Lee, F Eun-Hyung, Sanz, Inãki, Qiu, Peng
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Duan, Meixue, Nguyen, Doan C., Joyner, Chester J., Saney, Celia L., Tipton, Christopher M., Andrews, Joel, Lonial, Sagar, Kim, Caroline, Hentenaar, Ian, Kosters, Astrid, Ghosn, Eliver, Jackson, Annette, Knechtle, Stuart, Maruthamuthu, Stalinraja, Chandran, Sindhu, Martin, Tom, Rajalingam, Raja, Vincenti, Flavio, Breeden, Cynthia, Sanz, Ignacio, Gibson, Greg, Lee, F. Eun-Hyung
Published in Cell reports (Cambridge) (25.07.2023)
Published in Cell reports (Cambridge) (25.07.2023)
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Distinct transcriptomes and autocrine cytokines underpin maturation and survival of antibody-secreting cells in systemic lupus erythematosus
Chen, Weirong, Hong, So-Hee, Jenks, Scott A., Anam, Fabliha A., Tipton, Christopher M., Woodruff, Matthew C., Hom, Jennifer R., Cashman, Kevin S., Faliti, Caterina Elisa, Wang, Xiaoqian, Kyu, Shuya, Wei, Chungwen, Scharer, Christopher D., Mi, Tian, Hicks, Sakeenah, Hartson, Louise, Nguyen, Doan C., Khosroshahi, Arezou, Lee, Saeyun, Wang, Youliang, Bugrovsky, Regina, Ishii, Yusho, Lee, F. Eun-Hyung, Sanz, Ignacio
Published in Nature communications (01.03.2024)
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Trück, Johannes, Eugster, Anne, Barennes, Pierre, Tipton, Christopher M, Luning Prak, Eline T, Bagnara, Davide, Soto, Cinque, Sherkow, Jacob S, Payne, Aimee S, Lefranc, Marie-Paule, Farmer, Andrew, Bostick, Magnolia, Mariotti-Ferrandiz, Encarnita
Published in eLife (26.05.2021)
Published in eLife (26.05.2021)
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Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus
Jenks, Scott A., Cashman, Kevin S., Zumaquero, Esther, Marigorta, Urko M., Patel, Aakash V., Wang, Xiaoqian, Tomar, Deepak, Woodruff, Matthew C., Simon, Zoe, Bugrovsky, Regina, Blalock, Emily L., Scharer, Christopher D., Tipton, Christopher M., Wei, Chungwen, Lim, S. Sam, Petri, Michelle, Niewold, Timothy B., Anolik, Jennifer H., Gibson, Greg, Eun-Hyung Lee, F., Boss, Jeremy M., Lund, Frances E., Sanz, Ignacio
Published in Immunity (Cambridge, Mass.) (14.01.2020)
Published in Immunity (Cambridge, Mass.) (14.01.2020)
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Elucidation of seventeen human peripheral blood B‐cell subsets and quantification of the tetanus response using a density‐based method for the automated identification of cell populations in multidimensional flow cytometry data
Qian, Yu, Wei, Chungwen, Eun‐Hyung Lee, F., Campbell, John, Halliley, Jessica, Lee, Jamie A., Cai, Jennifer, Kong, Y. Megan, Sadat, Eva, Thomson, Elizabeth, Dunn, Patrick, Seegmiller, Adam C., Karandikar, Nitin J., Tipton, Christopher M., Mosmann, Tim, Sanz, Iñaki, Scheuermann, Richard H.
Published in Cytometry. Part B, Clinical cytometry (2010)
Published in Cytometry. Part B, Clinical cytometry (2010)
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Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19
Woodruff, Matthew C., Ramonell, Richard P., Nguyen, Doan C., Cashman, Kevin S., Saini, Ankur Singh, Haddad, Natalie S., Ley, Ariel M., Kyu, Shuya, Howell, J. Christina, Ozturk, Tugba, Lee, Saeyun, Suryadevara, Naveenchandra, Case, James Brett, Bugrovsky, Regina, Chen, Weirong, Estrada, Jacob, Morrison-Porter, Andrea, Derrico, Andrew, Anam, Fabliha A., Sharma, Monika, Wu, Henry M., Le, Sang N., Jenks, Scott A., Tipton, Christopher M., Staitieh, Bashar, Daiss, John L., Ghosn, Eliver, Diamond, Michael S., Carnahan, Robert H., Crowe, James E., Hu, William T., Lee, F. Eun-Hyung, Sanz, Ignacio
Published in Nature immunology (01.12.2020)
Published in Nature immunology (01.12.2020)
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Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow
Halliley, Jessica L, Tipton, Christopher M, Liesveld, Jane, Rosenberg, Alexander F, Darce, Jaime, Gregoretti, Ivan V, Popova, Lana, Kaminiski, Denise, Fucile, Christopher F, Albizua, Igor, Kyu, Shuya, Chiang, Kuang-Yueh, Bradley, Kyle T, Burack, Richard, Slifka, Mark, Hammarlund, Erika, Wu, Hao, Zhao, Liping, Walsh, Edward E, Falsey, Ann R, Randall, Troy D, Cheung, Wan Cheung, Sanz, Iñaki, Lee, F Eun-Hyung
Published in Immunity (Cambridge, Mass.) (21.07.2015)
Published in Immunity (Cambridge, Mass.) (21.07.2015)
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Long-Lived Plasma Cells Are Contained within the CD19−CD38hiCD138+ Subset in Human Bone Marrow
Halliley, Jessica L., Tipton, Christopher M., Liesveld, Jane, Rosenberg, Alexander F., Darce, Jaime, Gregoretti, Ivan V., Popova, Lana, Kaminiski, Denise, Fucile, Christopher F., Albizua, Igor, Kyu, Shuya, Chiang, Kuang-Yueh, Bradley, Kyle T., Burack, Richard, Slifka, Mark, Hammarlund, Erika, Wu, Hao, Zhao, Liping, Walsh, Edward E., Falsey, Ann R., Randall, Troy D., Cheung, Wan Cheung, Sanz, Iñaki, Lee, F. Eun-Hyung
Published in Immunity (Cambridge, Mass.) (01.07.2015)
Published in Immunity (Cambridge, Mass.) (01.07.2015)
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Dysregulated naive B cells and de novo autoreactivity in severe COVID-19
Woodruff, Matthew C., Ramonell, Richard P., Haddad, Natalie S., Anam, Fabliha A., Rudolph, Mark E., Walker, Tiffany A., Truong, Alexander D., Dixit, Adviteeya N., Han, Jenny E., Cabrera-Mora, Monica, Runnstrom, Martin C., Bugrovsky, Regina, Hom, Jennifer, Connolly, Erin C., Albizua, Igor, Javia, Vidhi, Cashman, Kevin S., Nguyen, Doan C., Kyu, Shuya, Singh Saini, Ankur, Piazza, Michael, Tipton, Christopher M., Khosroshahi, Arezou, Gibson, Greg, Martin, Greg S., Maier, Cheryl L., Esper, Annette, Jenks, Scott A., Lee, F. Eun-Hyung, Sanz, Ignacio
Published in Nature (London) (03.11.2022)
Published in Nature (London) (03.11.2022)
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A transcriptionally distinct subset of influenza-specific effector memory B cells predicts long-lived antibody responses to vaccination in humans
Nellore, Anoma, Zumaquero, Esther, Scharer, Christopher D., Fucile, Christopher F., Tipton, Christopher M., King, R. Glenn, Mi, Tian, Mousseau, Betty, Bradley, John E., Zhou, Fen, Mutneja, Stuti, Goepfert, Paul A., Boss, Jeremy M., Randall, Troy D., Sanz, Ignacio, Rosenberg, Alexander F., Lund, Frances E.
Published in Immunity (Cambridge, Mass.) (11.04.2023)
Published in Immunity (Cambridge, Mass.) (11.04.2023)
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Plasmodium falciparum-specific IgM B cells dominate in children, expand with malaria, and produce functional IgM
Hopp, Christine S, Sekar, Padmapriya, Diouf, Ababacar, Miura, Kazutoyo, Boswell, Kristin, Skinner, Jeff, Tipton, Christopher M, Peterson, Mary E, Chambers, Michael J, Andrews, Sarah, Lu, Jinghua, Tan, Joshua, Li, Shanping, Doumbo, Safiatou, Kayentao, Kassoum, Ongoiba, Aissata, Traore, Boubacar, Portugal, Silvia, Sun, Peter D, Long, Carole, Koup, Richard A, Long, Eric O, McDermott, Adrian B, Crompton, Peter D
Published in The Journal of experimental medicine (05.04.2021)
Published in The Journal of experimental medicine (05.04.2021)
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