Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue
Litchfield, Kevin, Spain, Lavinia, Gallegos, Lisa L., Schnidrig, Desiree, Rosenbaum, Heidi, Au, Lewis, Hill, Samantha M., Thomas, Jennifer, Thompson, Lisa, Horswell, Stuart, Jones, Carol, Burgess, Daniel L., Watkins, Thomas B.K., Lim, Emilia, Birkbak, Nicolai J., Nordentoft, Iver, Pickering, Lisa, Jamal-Hanjani, Mariam, Shiu, Kai-Keen, Bridgewater, John, Hochhauser, Daniel, Forster, Martin, Papadatos-Pastos, Dionysis, Enfield, Katey, McGranahan, Nicholas, Huebner, Ariana, Parker, Peter, Walczak, Henning, Proctor, Ian, Lok, Chi-wah, Moore, David, Marafioti, Teresa, Mitchison, Miriam, Trevisan, Giorgia, Ellery, Peter, Veeriah, Selvaraju, Razaq, Maryam, Shaw, Heather, Manzano, Lizi, Summan, Simranpreet, Kanu, Nnenna, Asghar, Uzma, Tookman, Adrian, Stirling, Caroline, Edmonds, Kim, Hunter, Nikki, Mangwende, Mary, Pearce, Karla, Yan, Haixi, Fendler, Annika, Byrne, Fiona, Popat, Sanjay, Curtis, Olivia, Toncheva, Antonia, Murra, Aida, Korteweg, Justine, Josephs, Debra, Chandra, Ashish, Spicer, James, Mahadeva, Ula, Green, Anna, Stewart, Ruby, Iredale, Lara-Rose, Mackay, Tina, Deakin, Ben, Enting, Debra, Rudman, Sarah, Ghosh, Sharmistha, Karapagniotou, Lena, Pintus, Elias, Tutt, Andrew, Michalarea, Vasiliki, Brenton, James, Caldas, Carlos, Fitzgerald, Rebecca, Jimenez-Linan, Merche, Provenzano, Elena, Cluroe, Alison, Gilbertson, Richard, McDermott, Ultan, Tavare, Simon, Beddowes, Emma, Fraser, Sioban, Krebs, Matt, Dransfield, Jo, Le Quesne, John, Fennell, Dean, Langman, Gerald, Robinson, Andrew, Collard, Martin, Cockcroft, Peter, Ferris, Charlotte, Bancroft, Hollie, Kerr, Amy, Wilson, Rodelaine, Tomlinson, Ian, Loda, Massimo, McKenzie, Mairead, Larkin, James, Turajlic, Samra
Published in Cell reports (Cambridge) (05.05.2020)
Published in Cell reports (Cambridge) (05.05.2020)
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Journal Article
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma
Culliford, Richard, Lawrence, Samuel E. D., Mills, Charlie, Tippu, Zayd, Chubb, Daniel, Cornish, Alex J., Browning, Lisa, Kinnersley, Ben, Bentham, Robert, Sud, Amit, Pallikonda, Husayn, Frangou, Anna, Gruber, Andreas J., Litchfield, Kevin, Wedge, David, Larkin, James, Turajlic, Samra, Houlston, Richard S.
Published in Nature communications (15.07.2024)
Published in Nature communications (15.07.2024)
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Journal Article
Impact of age on the toxicity of immune checkpoint inhibition
Samani, Amit, Zhang, Shuai, Spiers, Laura, Suwaidan, Ali Abdulnabi, Merrick, Sophie, Tippu, Zayd, Payne, Miranda, Faust, Guy, Papa, Sophie, Fields, Paul, Van Hemelrijck, Mieke, Josephs, Debra H
Published in Journal for immunotherapy of cancer (01.10.2020)
Published in Journal for immunotherapy of cancer (01.10.2020)
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Journal Article
How we treat neurological toxicity from immune checkpoint inhibitors
Spain, Lavinia, Tippu, Zayd, Larkin, James M, Carr, Aisling, Turajlic, Samra
Published in ESMO open (01.07.2019)
Published in ESMO open (01.07.2019)
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Journal Article
A protocol for representative sampling of solid tumors to improve the accuracy of sequencing results
Gallegos, Lisa L., Gilchrist, Ashley, Spain, Lavinia, Stanislaw, Stacey, Hill, Samantha M., Primus, Vanessa, Jones, Carol, Agrawal, Somya, Tippu, Zayd, Barhoumi, Aoune, Noel-Storr, Glenn, Alexander, Nelson R., Turajlic, Samra
Published in STAR protocols (17.09.2021)
Published in STAR protocols (17.09.2021)
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Journal Article
Ethnicity Recording in Primary Care Computerised Medical Record Systems: An Ontological Approach
Tippu, Zayd, Correa, Ana, Liyanage, Harshana, Burleigh, David, McGovern, Andrew, Van Vlymen, Jeremy, Jones, Simon, De Lusignan, Simon
Published in BMJ health & care informatics (14.03.2017)
Published in BMJ health & care informatics (14.03.2017)
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Journal Article
Defining the true impact of coronavirus disease 2019 in the at-risk population of patients with cancer
Angelis, Vasileios, Tippu, Zayd, Joshi, Kroopa, Reis, Sara, Gronthoud, Firza, Fribbens, Charlotte, Okines, Alicia, Stanway, Susannah, Cottier, Emma, McGrath, Sophie, Watkins, David, Noble, Jillian, Bhosle, Jaishree, Gerlinger, Marco, Hamid, Intan, Soliman, Heba, Nenclares, Pablo, Jones, Robin, Harrington, Kevin, Gennatas, Spyridon
Published in European journal of cancer (1990) (01.09.2020)
Published in European journal of cancer (1990) (01.09.2020)
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Journal Article
Omicron neutralising antibodies after third COVID-19 vaccine dose in patients with cancer
Fendler, Annika, Shepherd, Scott T C, Au, Lewis, Wu, Mary, Harvey, Ruth, Schmitt, Andreas M, Tippu, Zayd, Shum, Benjamin, Farag, Sheima, Rogiers, Aljosja, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Barber, Taja, Emslie-Henry, Andrea, Caulfield-Lynch, Niamh, Byrne, Fiona, Deng, Daqi, Kjaer, Svend, Song, Ok-Ryul, Queval, Christophe, Kavanagh, Caitlin, Wall, Emma C, Carr, Edward J, Caidan, Simon, Gavrielides, Mike, MacRae, James I, Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O'Flaherty, Molly, Shea, Robyn L, Gardner, Gail, Murray, Darren, Yousaf, Nadia, Jhanji, Shaman, Tatham, Kate, Cunningham, David, Van As, Nicholas, Young, Kate, Furness, Andrew J S, Pickering, Lisa, Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David L V, Kassiotis, George, Howell, Michael, Nicholson, Emma, Walker, Susanna, Larkin, James, Turajlic, Samra
Published in The Lancet (British edition) (05.03.2022)
Published in The Lancet (British edition) (05.03.2022)
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Journal Article
Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer
Fendler, Annika, Shepherd, Scott T.C., Au, Lewis, Wilkinson, Katalin A., Wu, Mary, Schmitt, Andreas M., Tippu, Zayd, Farag, Sheima, Rogiers, Aljosja, Harvey, Ruth, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Barber, Taja, Emslie-Henry, Andrea, Caulfield-Lynch, Niamh, Byrne, Fiona, Shum, Benjamin, Gerard, Camille L., Deng, Daqi, Kjaer, Svend, Song, Ok-Ryul, Queval, Christophe, Kavanagh, Caitlin, Wall, Emma C., Carr, Edward J., Namjou, Sina, Caidan, Simon, Gavrielides, Mike, MacRae, James I., Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O’Flaherty, Molly, Shea, Robyn L., Gardner, Gail, Murray, Darren, Popat, Sanjay, Yousaf, Nadia, Jhanji, Shaman, Van As, Nicholas, Young, Kate, Furness, Andrew J.S., Pickering, Lisa, Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David L.V., Kassiotis, George, Howell, Michael, Nicholson, Emma, Walker, Susanna, Wilkinson, Robert J., Larkin, James, Turajlic, Samra
Published in Cancer cell (14.02.2022)
Published in Cancer cell (14.02.2022)
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Journal Article
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: The CAPTURE study
Fendler, Annika, Shepherd, Scott T C, Au, Lewis, Wilkinson, Katalin A, Wu, Mary, Byrne, Fiona, Cerrone, Maddalena, Schmitt, Andreas M, Joharatnam-Hogan, Nalinie, Shum, Benjamin, Tippu, Zayd, Rzeniewicz, Karolina, Boos, Laura Amanda, Harvey, Ruth, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Sarker, Sarah, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Bazin, Jessica, Gordon, William, Barber, Taja, Emslie-Henry, Andrea, Xie, Wenyi, Gerard, Camille L, Deng, Daqi, Wall, Emma C, Agua-Doce, Ana, Namjou, Sina, Caidan, Simon, Gavrielides, Mike, MacRae, James I, Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O'Flaherty, Molly, Dowdie, Lauren, Ash, Natalie, Gronthoud, Firza, Shea, Robyn L, Gardner, Gail, Murray, Darren, Kinnaird, Fiona, Cui, Wanyuan, Pascual, Javier, Rodney, Simon, Mencel, Justin, Curtis, Olivia, Stephenson, Clemency, Robinson, Anna, Oza, Bhavna, Farag, Sheima, Leslie, Isla, Rogiers, Aljosja, Iyengar, Sunil, Ethell, Mark, Messiou, Christina, Cunningham, David, Chau, Ian, Starling, Naureen, Turner, Nicholas, Welsh, Liam, van As, Nicholas, Jones, Robin L, Droney, Joanne, Banerjee, Susana, Tatham, Kate C, O'Brien, Mary, Harrington, Kevin, Bhide, Shreerang, Okines, Alicia, Reid, Alison, Young, Kate, Furness, Andrew J S, Pickering, Lisa, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David Lv, Kassiotis, George, Kumar, Sacheen, Yousaf, Nadia, Jhanji, Shaman, Nicholson, Emma, Howell, Michael, Walker, Susanna, Wilkinson, Robert J, Larkin, James, Turajlic, Samra
Published in Nature cancer (01.12.2021)
Published in Nature cancer (01.12.2021)
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Late-Stage Metastatic Melanoma Emerges through a Diversity of Evolutionary Pathways
Spain, Lavinia, Coulton, Alexander, Lobon, Irene, Rowan, Andrew, Schnidrig, Desiree, Shepherd, Scott T C, Shum, Benjamin, Byrne, Fiona, Goicoechea, Maria, Piperni, Elisa, Au, Lewis, Edmonds, Kim, Carlyle, Eleanor, Hunter, Nikki, Renn, Alexandra, Messiou, Christina, Hughes, Peta, Nobbs, Jaime, Foijer, Floris, van den Bos, Hilda, Wardenaar, Rene, Spierings, Diana C J, Spencer, Charlotte, Schmitt, Andreas M, Tippu, Zayd, Lingard, Karla, Grostate, Lauren, Peat, Kema, Kelly, Kayleigh, Sarker, Sarah, Vaughan, Sarah, Mangwende, Mary, Terry, Lauren, Kelly, Denise, Biano, Jennifer, Murra, Aida, Korteweg, Justine, Lewis, Charlotte, O'Flaherty, Molly, Cattin, Anne-Laure, Emmerich, Max, Gerard, Camille L, Pallikonda, Husayn Ahmed, Lynch, Joanna, Mason, Robert, Rogiers, Aljosja, Xu, Hang, Huebner, Ariana, McGranahan, Nicholas, Al Bakir, Maise, Murai, Jun, Naceur-Lombardelli, Cristina, Borg, Elaine, Mitchison, Miriam, Moore, David A, Falzon, Mary, Proctor, Ian, Stamp, Gordon W H, Nye, Emma L, Young, Kate, Furness, Andrew J S, Pickering, Lisa, Stewart, Ruby, Mahadeva, Ula, Green, Anna, Larkin, James, Litchfield, Kevin, Swanton, Charles, Jamal-Hanjani, Mariam, Turajlic, Samra
Published in Cancer discovery (02.06.2023)
Published in Cancer discovery (02.06.2023)
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Journal Article
Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer
Fendler, Annika, Shepherd, Scott T.C., Au, Lewis, Wilkinson, Katalin A., Wu, Mary, Schmitt, Andreas M., Tippu, Zayd, Farag, Sheima, Rogiers, Aljosja, Harvey, Ruth, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Barber, Taja, Emslie-Henry, Andrea, Caulfield-Lynch, Niamh, Byrne, Fiona, Shum, Benjamin, Gerard, Camille L., Deng, Daqi, Kjaer, Svend, Song, Ok-Ryul, Queval, Christophe, Kavanagh, Caitlin, Wall, Emma C., Carr, Edward J., Namjou, Sina, Caidan, Simon, Gavrielides, Mike, MacRae, James I., Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O’Flaherty, Molly, Shea, Robyn L., Gardner, Gail, Murray, Darren, Popat, Sanjay, Yousaf, Nadia, Jhanji, Shaman, Van As, Nicholas, Young, Kate, Furness, Andrew J.S., Pickering, Lisa, Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David L.V., Kassiotis, George, Howell, Michael, Nicholson, Emma, Walker, Susanna, Wilkinson, Robert J., Larkin, James, Turajlic, Samra
Published in Cancer cell (11.04.2022)
Published in Cancer cell (11.04.2022)
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Journal Article
Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study
Fendler, Annika, Au, Lewis, Shepherd, Scott T C, Byrne, Fiona, Cerrone, Maddalena, Boos, Laura Amanda, Rzeniewicz, Karolina, Gordon, William, Shum, Benjamin, Gerard, Camille L, Ward, Barry, Xie, Wenyi, Schmitt, Andreas M, Joharatnam-Hogan, Nalinie, Cornish, Georgina H, Pule, Martin, Mekkaoui, Leila, Ng, Kevin W, Carlyle, Eleanor, Edmonds, Kim, Rosario, Lyra Del, Sarker, Sarah, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Stone, Richard, Gomes, Camila, Flynn, Helen R, Agua-Doce, Ana, Hobson, Philip, Caidan, Simon, Howell, Michael, Wu, Mary, Goldstone, Robert, Crawford, Margaret, Cubitt, Laura, Patel, Harshil, Gavrielides, Mike, Nye, Emma, Snijders, Ambrosius P, MacRae, James I, Nicod, Jerome, Gronthoud, Firza, Shea, Robyn L, Messiou, Christina, Cunningham, David, Chau, Ian, Starling, Naureen, Turner, Nicholas, Welsh, Liam, van As, Nicholas, Jones, Robin L, Droney, Joanne, Banerjee, Susana, Tatham, Kate C, Jhanji, Shaman, O'Brien, Mary, Curtis, Olivia, Harrington, Kevin, Bhide, Shreerang, Bazin, Jessica, Robinson, Anna, Stephenson, Clemency, Slattery, Tim, Khan, Yasir, Tippu, Zayd, Leslie, Isla, Gennatas, Spyridon, Okines, Alicia, Reid, Alison, Young, Kate, Furness, Andrew J S, Pickering, Lisa, Gandhi, Sonia, Gamblin, Steve, Swanton, Charles, Nicholson, Emma, Kumar, Sacheen, Yousaf, Nadia, Wilkinson, Katalin A, Swerdlow, Anthony, Harvey, Ruth, Kassiotis, George, Larkin, James, Wilkinson, Robert J, Turajlic, Samra
Published in Nature cancer (01.12.2021)
Published in Nature cancer (01.12.2021)
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Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer
Wu, Mary Y., Shepherd, Scott T.C., Fendler, Annika, Carr, Edward J., Au, Lewis, Harvey, Ruth, Dowgier, Giulia, Hobbs, Agnieszka, Herman, Lou S., Ragno, Martina, Adams, Lorin, Schmitt, Andreas M., Tippu, Zayd, Shum, Benjamin, Farag, Sheima, Rogiers, Aljosja, O’Reilly, Nicola, Bawumia, Philip, Smith, Callie, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Barber, Taja, Hepworth, Stephanie, Emslie-Henry, Andrea, Caulfield-Lynch, Niamh, Byrne, Fiona, Deng, Daqi, Williams, Bryan, Brown, Michael, Caidan, Simon, Gavrielides, Mike, MacRae, James I., Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O’Flaherty, Molly, Popat, Sanjay, Yousaf, Nadia, Jhanji, Shaman, Tatham, Kate, Cunningham, David, Van As, Nicholas, Young, Kate, Furness, Andrew J.S., Pickering, Lisa, Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David L.V., Kassiotis, George, Howell, Michael, Walker, Susanna, Nicholson, Emma, Larkin, James, Wall, Emma C., Turajlic, Samra
Published in Cancer cell (08.05.2023)
Published in Cancer cell (08.05.2023)
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Copy number architectures define treatment-mediated selection of lethal prostate cancer clones
Hasan, A. M. Mahedi, Cremaschi, Paolo, Wetterskog, Daniel, Jayaram, Anuradha, Wong, Stephen Q., Williams, Scott, Pasam, Anupama, Trigos, Anna, Trujillo, Blanca, Grist, Emily, Friedrich, Stefanie, Vainauskas, Osvaldas, Parry, Marina, Ismail, Mazlina, Devlies, Wout, Wingate, Anna, Linch, Mark, Naceur-Lombardelli, Cristina, Swanton, Charles, Jamal-Hanjani, Mariam, Lise, Stefano, Sandhu, Shahneen, Attard, Gerhardt
Published in Nature communications (10.08.2023)
Published in Nature communications (10.08.2023)
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Journal Article
Systematic review of adherence rates by medication class in type 2 diabetes: a study protocol
McGovern, Andrew, Tippu, Zayd, Hinton, William, Munro, Neil, Whyte, Martin, de Lusignan, Simon
Published in BMJ open (29.02.2016)
Published in BMJ open (29.02.2016)
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Journal Article
The impact of patient age on toxicity and efficacy of immunotherapy agents
Zhang, Shuai, Samani, Amit, Spiers, Laura, Tippu, Zayd, Suwaidan, Ali Abdulnabi, Merrick, Sophie, Van Hemelrijck, Mieke, Payne, Miranda, Faust, Guy, Papa, Sophie, Josephs, Debra Hannah
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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